I was doing crystallography of bacterial and phage proteins. What ever i knew about epigenetic control was long outdated. I needed a comprehensive introduction and review on this field. This book was an excellent starter for me. It gave an excellent introduction and why's and how's of epigenetic control of eukaryotic genome and its mechanisms. I am now eagerly waiting for a second edition with all the updates that has happened in the last 10 years.
Author(s): B. M. Turner
Edition: 1
Publisher: Wiley-Blackwell
Year: 2002
Language: English
Pages: 295
Cover......Page 1
Chromatin and Gene Regulation......Page 2
Contents......Page 6
Preface......Page 9
Prologue......Page 11
1 Controlling Transcription: Shared Aims and Common Mechanisms......Page 17
2 Transcription in Eukaryotes: The Problems of Complexity......Page 35
3 The Nucleosome: Chromatin's Structural Unit......Page 54
4 Histone Tails: Modifications and Epigenetic Information......Page 69
5 Higher-Order Chromatin Structures and Nuclear Organization......Page 85
6 Transcription in a Chromatin Environment......Page 111
7 How the Transcription Machinery Deals With Chromatin......Page 136
8 Chromatin Remodelling Machines......Page 156
9 Heterochromatin......Page 182
10 Long-Term Silencing of Gene Expression......Page 206
11 Cellular Memory and Imprinting......Page 231
12 Mechanisms of Dosage Compensation......Page 259
Index......Page 285
Back Cover......Page 295
