Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products. Beginning with a general introduction to set the context, the authors then go on to carefully detail nomenclature, occurrence, isolation, detection, structure elucidation (by both degradation and spectroscopic techniques) stereochemistry, conformation, synthesis, biosynthesis, biological activity and commercial applications of the most important natural products of plant origin. Each chapter also includes detailed references (with titles) and a list of recommended books for additional study making this outstanding treatise a useful resource for teachers of chemistry and researchers working in universities, research institutes and industry.
Author(s): Sunil Kumar Talapatra, Bani Talapatra (auth.)
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2015
Language: English
Pages: 1180
Tags: Organic Chemistry; Medicinal Chemistry; Pharmacology/Toxicology; Biochemistry, general; Pharmacy
Front Matter....Pages i-lxiii
Introduction: Enzymes. Cofactors/Coenzymes. Primary and Secondary Metabolites. Natural Products and their Functions. Plant Chemical Ecology. Biosynthesis. Metabolic Pathways....Pages 1-22
Fundamental Stereochemical Concepts and Nomenclatures....Pages 23-201
Important Biological Events Occurring in Plants....Pages 203-241
Natural Products Chemistry: A General Treatment....Pages 243-316
Biosynthesis of Terpenoids: The Oldest Natural Products....Pages 317-344
Monoterpenoids (C 10 )....Pages 345-401
Sesquiterpenoids (C 15 )....Pages 403-468
Diterpenoids (C 20 )....Pages 469-510
Sesterterpenoids (C 25 )....Pages 511-515
Triterpenes (C 30 )....Pages 517-552
Steroids: Cholesterol and Other Phytosterols....Pages 553-583
Carotenoids: GGPP-Derived Polyisoprenoid (C 40 ) Coloring Pigments....Pages 585-594
Shikimic Acid Pathway....Pages 625-678
Polyketide Pathway. Biosynthesis of Diverse Classes of Aromatic Compounds....Pages 679-715
Alkaloids. General Introduction....Pages 717-724
Hygrine, Hygroline, and Cuscohygrine ( Ornithine-Derived Alkaloids )....Pages 725-732
Coniine, Conhydrine, and Pseudoconhydrine ( The C-Skeleton Derived from a C 8 -Fatty Acid and N from Transamination )....Pages 733-748
Nicotine ( Pyridine - Pyrrolidine Alkaloid , Derived from l - Aspartic Acid and l - Ornithine )....Pages 749-766
Atropine [(±)-Hyoscyamine] and Cocaine ( Ornithine - Derived Alkaloids )....Pages 767-780
Ephedrine and Pseudoephedrine (C 6 –C 1 Part Derived from l -Phenylalanine and Nitrogen Derived by Transamination)....Pages 781-791
Pilocarpine and Isopilocarpine ( l -Histidine-Derived Imidazole Alkaloids)....Pages 793-801
Papaverine ( l -Tyrosine-Derived Alkaloid)....Pages 803-809
Morphine. Codeine. Thebaine: Modified Benzyltetrahydroisoquinoline Alkaloids ....Pages 811-841
Colchicine, A Phenylethylisoquinoline Alkaloid Derived from L-Tyrosine ....Pages 843-854
Quinine. Cinchona Alkaloids ( Tryptophan Derived Quinoline Alkaloids )....Pages 855-874
Reserpine....Pages 875-890
Strychnine, an Alkaloid with Heptacyclic Dense Molecular Scaffold ....Pages 891-900
Dimeric Indole Alkaloids. Vinblastine (Vincaleukoblastine), Vincristine (Leurocristine), and Their Derivatives....Pages 901-907
Camptothecin, A Novel Pyrrolo[3,4-b]quinoline Alkaloid: Derived by Modification of an Indole System....Pages 909-913
Some More Alkaloids Having Diverse Skeletal Patterns....Pages 915-922
Important Outcomes of Chemical Studies on Natural Products....Pages 923-952
Chiral Recognition in Biological Systems and Natural Chiral Auxiliaries....Pages 953-975
Natural Products in the Parlor of Pharmaceuticals....Pages 977-1009
Organic Phytonutrients, Vitamins, and Antioxidants....Pages 1011-1037
Back Matter....Pages 1039-1180
