Content: Preparative and analytical high performance liquid chromatography of glycolipids / R.H. McCluer and M.D. Ullman --
High performance liquid chromatography of membrane glycolipids : assessment of cerebrosides on the surface of myelin / Shoji Yahara, Yasuo Kishimoto, and Joseph Poduslo --
Analysis of glycosphingolipids by field desorption mass spectrometry / C.E. Costello, B.W. Wilson, K. Biemann, and V.N. Reinhold --
High resolution proton NMR spectra of blood-group active glycosphingolipids in DMSO-d6 / J. Dabrowski, H. Egge, P. Hanfland, and S. Kuhn --
Glycophosphoceramides from plants / Roger A. Laine, Thomas C.-Y. Hsieh, and Robert L. Lester --
Glycolipids of rat small intestine with special reference to epithelial cells in relation to differentiation / M.E. Breimer, G.C. Hansson, K.-A. Karlsson, and H. Leffler --
Galactoglycerolipids of mammalian testis, spermatozoa, and nervous tissue / Robert K. Murray, Rajagopolian Narasimhan, Mark Levine, Les Pinteric, Margaret Shirley, Clifford Lingwood, and Harry Schacter --
Structural studies of neutral glycosphingolipids of human neutrophils by electron impact/desorption mass spectrometry / Bruce A. Macher and John C. Klock --
Glycosphingolipids of skeletal muscle / Jaw-Long Chien and Edward L. Hogan --
Glycosphingolipids and glyceroglucolipids of glandular epithelial tissue / Bronislaw L. Slomiany and Amalia Slomiany --
Fucolipids and gangliosides of human colonic cell lines / Bader Siddiqui and Y.S. Kim --
Biosynthesis of blood-group related glycosphingolipids in T- and B-lymphomas and neuroblastoma cells / Manju Basu, Subhash Basu, and Michael Potter --
Altered glycolipids of CHO cells resistant to wheat germ agglutinin / Pamela Stanley --
Induction of ganglioside biosynthesis in cultured cells by butyric acid / Peter H. Fishman and Richard C. Henneberry --
Regulation of glycoconjugate metabolism in normal and transformed cells / Joseph R. Moskal, Michael W. Lockney, Christopher C. Marvel, Peggy A. Mason, Charles C. Sweeley, Stephen T. Warren, and James E. Trosko --
Alterations in cell surface glycosphingolipids and their metabolism in familial hypercholesterolemic fibroblasts / S. Chatterjee, P.O. Kwiterovich, and C.S. Sekerke --
Biochemical, morphological, and regulatory aspects of myelination in cultures of dissociated brain cells from embryonic mice / Ronald A. Pieringer, Graham Lem. Campbell, Narayan R. Bhat, G. Subba Rao, and Louis L. Sarlieve --
Gangliosides and associated enzymes at the nerve-ending membranes / G. Tettamanti, A. Preti, B. Cestaro, M. Masserini, S. Sonnino, and R. Ghidoni --
Specificity and membrane properties of young rat brain sialyltransferases / Sai-Sun Ng and Joel A. Dain --
Modulation of ganglioside synthesis by enkephalins, opiates, and prostaglandins : role of cyclic AMP in glycosylation / Glyn Dawson, Ronald W. McLawhon, Gwendolyn Schoon, and R.J. Miller --
Gangliosides as receptors for cholera toxin, tetanus toxin, and sendai virus / Lars Svennerholm, P. Fredman, H. Elwing, J. Holmgren, and Ö. Strannegård --
Interferon-carbohydrate interaction / Helmut Ankel, Françoise Besancon, and Chita Krishnamurti --
Perturbation of behavior and other CNS functions by antibodies to ganglioside / Maurice M. Rapport, Stephen E. Karpiak, and Sahebarao P. Mahadik --
Immunological properties of gangliosides / A.J. Yates, C.L. Hitchcock, S.S. Stewart, and R.L. Whisler --
Ganglioside composition of rabbit thymus : molecular specificities compared with those of various organs / Yoshitaka Nagai and Masao Iwamori --
The immunology and immunochemistry of Thy-1 active glycolipids / W.J. Esselman, H.C. Miller, T.J. Wang, K.P. Kato, and W.G. Chaney --
Immune reactivities of antibodies against glycolipids : natural antibodies / Roberta L. Richards and Carl R. Alving.
Author(s): Charles C. Sweeley (Eds.)
Series: ACS Symposium Series 128
Publisher: American Chemical Society
Year: 1980
Language: English
Pages: 495
City: Washington, D.C
Title Page......Page 1
Copyright......Page 2
ACS Symposium Series......Page 3
FOREWORD......Page 4
PdftkEmptyString......Page 0
PREFACE......Page 5
Preparation and analysis of benzoylated cerebrosides......Page 6
Analysis of ceramides......Page 7
Quantitative analysis of neutral glycosphingolipids......Page 8
Preparative HPLC of per-0-benzoylated glycosphingolipids.......Page 13
Literature Cited......Page 16
2 High Performance Liquid Chromatography of Membrane Glycolipids Assessment of Cerebrosides on the Surface of Myelin......Page 19
Procedures......Page 20
Results......Page 25
Discussion......Page 32
Literature Cited......Page 36
3 Analysis of Glycosphingolipids by Field Desorption Mass Spectrometry......Page 38
Materials and Methods......Page 42
Results and Discussion......Page 43
Conclusions......Page 55
Literature Cited......Page 56
Methods......Page 58
Results and Discussion......Page 59
References......Page 67
5 Glycophosphoceramides from Plants......Page 68
PSL-I: The Major Glycophosphoceramide from Tobacco Leaves......Page 71
Methylation Analyses......Page 75
Acknowledgements......Page 79
Literature Cited......Page 80
6 Glycolipids of Rat Small Intestine with Special Reference to Epithelial Cells in Relation to Differentiation......Page 82
Non-Epithelial Tissue......Page 83
Epithelial Cells......Page 87
Differences between the two compartments and between strains......Page 95
Epithelial Cells of Different Location and Maturity......Page 98
Discussion......Page 101
References......Page 106
7 Galactoglycerolipids of Mammalian Testis, Spermatozoa, and Nervous Tissue......Page 108
Nomenclature, Classification and Tissue Distribution......Page 109
Chemical Characterization of Galactosylalkylacylglycerols......Page 110
Biosynthesis of Testicular and Other Galactoglycerolipids......Page 114
Catabolism of SGG......Page 116
Appearance of Sulfatides During Testicular Development......Page 117
Attempted Labelling of Galactoglycerolipids Using Galactose Oxidase......Page 119
Sulfogalactolipids of the Testis of Various Species......Page 120
Galactoglycerolipids of the Nervous System......Page 122
Conclusion......Page 124
Literature Cited......Page 125
Materials and Methods......Page 129
Results......Page 130
Discussion......Page 135
Literature Cited......Page 136
9 Glycosphingolipids of Skeletal Muscle......Page 137
DEAE-Sephadex Column Chromatography......Page 138
Enzymatic Hydrolysis Employing Glycosidases......Page 139
Results......Page 140
Discussion......Page 145
Acknowledgment......Page 148
Literature Cited......Page 149
10 Glycosphingolipids and Glyceroglucolipids of Glandular Epithelial Tissue......Page 151
The Glycosphingolipids of Gastric Mucosa and Salivary Glands......Page 152
Glycolipids of Mucous Secretion......Page 168
The Nature of ABH Blood Group Antigens in Mucous Secretion......Page 172
Literature Cited......Page 175
11 Fucolipids and Gangliosides of Human Colonic Cell Lines......Page 179
Materials and Methods......Page 180
Results......Page 181
Discussion......Page 184
Summary......Page 186
Literature Cited......Page 187
12 Biosynthesis of Blood-Group Related Glycosphingolipids in T- and B-Lymphomas and Neuroblastoma Cells......Page 189
Materials and Methods......Page 190
Results and Discussion......Page 199
Acknowledgments......Page 210
Literature Cited......Page 211
Materials and Methods......Page 215
Thin Layer Chromatography.......Page 216
Results......Page 217
Discussion......Page 222
Literature Cited......Page 223
Effects of Butyrate on Cell Morphology......Page 224
Induction of GM3 Biosynthesis by Butyrate......Page 225
Induction of Choleragen Receptors by Butyrate......Page 229
Evidence that GM1 is the Choleragen Receptor......Page 231
Effects of Cycloheximide......Page 234
LITERATURE CITED......Page 238
Introduction......Page 241
Methods......Page 246
Results and Discussion......Page 248
Conclusions......Page 259
Literature Cited......Page 260
Plasma Glycosphingolipids and Lipoproteins......Page 264
Glycosphingolipids and Lipoproteins......Page 266
Metabolism of Glycosphingolipids in Cultured Human Fibroblasts......Page 268
Glycosphingolipid and Lipoprotein Metabolism in Cultured Human Fibroblasts......Page 270
Biochemical Characterization of Fibroblasts......Page 272
Incubation of Co-cultured Cells with [3H] Galactose......Page 274
Measurement of Egress of Glycosphingolipids into the Culture Medium......Page 275
Glycosphingolipid Composition of Normal and Familial Hypercholesterolemic Cells......Page 276
Incorporation of Radioactive Leucine, Thymidine and 2-Deoxyglucose in Normal and Familial Hypercholesterolemic Fibroblasts......Page 278
Metabolic Labeling Pattern of Glycosphingolipids in Familial Hypercholesterolemic Heterozygous Fibroblasts and Co-cultured Normal and Familial Hypercholesterolemic Homozygous Fibroblasts......Page 281
Effects of Incubation of Fibroblasts with Lipoprotein Deficient Medium on the Incorporation of Radioactivity Derived from [3H] Galactose into Cellular Glycosphingolipids and Cell Culture Medium......Page 285
Discussion......Page 288
Literature Cited......Page 298
Footnotes......Page 301
17 Biochemical, Morphological, and Regulatory Aspects of Myelination in Cultures of Dissociated Brain Cells from Embryonic Mice......Page 302
Materials and Methods......Page 303
Results......Page 304
Discussion......Page 316
Literature Cited......Page 317
Chemical and physico-chemical properties of gangliosides: a molecular introduction to ganglioside behavior in cell plasma membranes.......Page 319
Ganglioside interactions......Page 322
Gangliosides, sialidase and sialyltransferase in the membranes surrounding nerve endings ( synaptosomal membranes )......Page 324
Ganglioside contribution to the supramolecular organization of synaptosoaml membranes......Page 329
An experimental model for the study of ganglioside behavior in synaptosomal membranes......Page 332
Literature cited......Page 339
19 Specificity and Membrane Properties of Young Rat Brain Sialyltransferases......Page 342
Results and Discussion......Page 343
Acknowledgement......Page 353
Literature Cited......Page 354
20 Modulation of Ganglioside Synthesis by Enkephalins, Opiates, and Prostaglandins Role of Cyclic AMP in Glycosylation......Page 356
Methods......Page 357
Results and Discussion......Page 358
Conclusions......Page 363
Literature Cited......Page 368
21 Gangliosides as Receptors for Cholera Toxin, Tetanus Toxin, and Sendai Virus......Page 370
Ligand methods......Page 371
Interaction between cholera toxin and ganglioside GMI......Page 372
Sendai virus......Page 380
Literature Cited......Page 384
Materials and Methods......Page 388
Effects of Glycolipids on Antiviral Activity of Fibroblast Interferon.......Page 390
Effects of Saccharides on Antiviral Activity of Fibroblast Interferon.......Page 392
Effect of Gangliosides on Antigrowth Activity of Fibroblast Interferon.......Page 394
Effects of Glycolipids on T-cell interferon (19).......Page 396
Effect of T-cell Interferon on Growth of L-1210S and L-1210R Cells (19).......Page 398
Discussion......Page 400
Literature Cited:......Page 401
Antibodies As A Bridge Between Structure And Function......Page 403
Antibodies To Ganglioside Interfere With CNS Functions Selectively......Page 405
Mechanisms By Which Antibodies May Perturb CNS Functions......Page 406
Antibodies To GM1 Ganglioside Inhibit Dendritic Development......Page 408
Conclusions......Page 410
Literature Cited......Page 411
Effects of Exogenously Added Gangliosides on In Vitro Assays of Cellular Immunity......Page 414
Effects of Specific Gangliosides on Lymphoblastic Transformation.......Page 416
Discussion......Page 425
ACKNOWLEDGEMENTS......Page 426
LITERATURE CITED......Page 427
Materials And Methods......Page 429
Results And Discussion......Page 430
Literature Cited......Page 436
26 The Immunology and Immunochemistry of Thy-1 Active Glycolipids......Page 438
Materials and Methods......Page 439
Results......Page 441
Discussion......Page 450
Literature Cited......Page 451
Methods......Page 453
Results......Page 454
Discussion......Page 462
LITERATURE CITED......Page 464
A......Page 466
B......Page 467
C......Page 469
E......Page 473
F......Page 474
G......Page 476
H......Page 482
I......Page 483
L......Page 484
M......Page 485
O......Page 487
P......Page 488
R......Page 489
S......Page 490
T......Page 492
W......Page 494
