The best cardiovascular review available for the USMLE®, exam review, and course work
Cardiovascular Physiology, Ninth Edition is a concise and enjoyable way for you to gain a fundamental knowledge of the basic operating principles of the intact cardiovascular system and how those principles apply to clinical medicine. Succinct but thorough, it focuses on the facts and concepts you must know to get a solid “big picture” overview of how the cardiovascular system operates in normal and abnormal situations. No other text will prove more valuable in enhancing your ability to evaluate the myriad new information you will be exposed to throughout your career, than Cardiovascular Physiology.
There is no faster or more effective way to learn how the key principles of cardiovascular function apply to common and pathological challenges than this engagingly written, time-proven guide. Medical students will find it to be an outstanding review for the USMLE® Step 1 and experienced clinicians will find it be a valuable clinical refresher.
Features• NEW! Increased focus on cardiovascular energetics• “Perspectives” section in each chapter that identify important, currently unresolved issues • Clarifies the details of physiologic mechanisms and their role in pathologic states• Links cardiovascular physiology to diagnosis and treatment• Summarizes key concepts at the end of each chapter• Highlights must-know information with chapter objectives• Reinforces learning with study questions at the end of each chapter
Author(s): David Mohrman, Lois Heller
Series: CARDIOLOGY
Edition: 9th
Publisher: McGraw-Hill / LANGE
Year: 2018
Language: English
Pages: 398
Tags: Cardiovascular Physiology
Preface ix
Chapter 1 Overview of the Cardiovascular System 1
Objectives 1
Evolution and Homeostatic Role of the Cardiovascular System 2
Overall Design of the Cardiovascular System 4
The Basic Physics of Blood Flow 6
Material Transport by Blood Flow 8
The Heart 9
The Vasculature 15
Blood 18
Perspectives 19
Chapter 2 Characteristics of Cardiac Muscle Cells 23
Objectives 23
Electrical Activity of Cardiac Muscle Cells 24
Mechanical Activity of the Heart 39
Relating Cardiac Muscle Cell Mechanics to Ventricular Function 49
Perspectives 50
Chapter 3 The Heart Pump 53
Objectives 53
Cardiac Cycle 54
Determinants of Cardiac Output 61
Influences on Stroke Volume 61
Summary of Determinants of Cardiac Output 66
Summary of Sympathetic Neural Influences on Cardiac Function 68
Cardiac Energetics 69
Perspectives 73
Chapter 4 Measurements of Cardiac Function 76
Objectives 76
Measurement of Mechanical Function 76
Measurement of Cardiac Excitation-The Electrocardiogram 80
Perspectives 90
Chapter 5 Cardiac Abnormalities 93
Objectives 93
Electrical Abnormalities and Arrhythmias 93
Cardiac Valve Abnormalities 98
Perspectives 101
Chapter 6 The Peripheral Vascular System 104
Objectives 104
Transcapillary Transport 106
Resistance and Flow in Networks of Vessels 111
Normal Conditions in the Peripheral Vasculature 114
Measurement of Arterial Pressure 120
Determinants of Arterial Pressure 121
Perspectives 124
Chapter 7 Vascular Control 128
Objectives 128
Vascular Smooth Muscle 129
Control of Arteriolar Tone 134
Control of Venous Tone 144
Summary of Primary Vascular Control Mechanisms 145
Vascular Control in Specific Organs 146
Perspectives 156
Chapter 8 Hemodynamic Interactions 160
Objectives 160
Key System Components 161
Central Venous Pressure: An Indicator of Circulatory Status 163
Perspectives 173
Chapter 9 Regulation of Arterial Pressure 175
Objectives 175
Short-Term Regulation of Arterial Pressure 176
Long-Term Regulation of Arterial Pressure 187
Perspectives 192
Chapter 10 Cardiovascular Responses to Physiological Stresses 197
Objectives 197
Primary Disturbances and Compensatory Responses 199
Effect of Respiratory Activity 199
Effect of Gravity 202
Effect of Exercise 208
Normal Cardiovascular Adaptations 213
Perspectives 217
Chapter 11 Cardiovascular Function in Pathological Situations 221
Objectives 221
Circulatory Shock 222
Cardiac Disturbances 228
Hypertension 238
Perspectives 242
Answers to Study Questions 246
Appendix A 265
Appendix B 266
Appendix C 267
Appendix D 268
Appendix E 270
Index 275
