The Carbohydrate Bioengineering Meeting held in Elsinore, Denmark, April 23-26, 1995, gathered 230 scientists, mostly from Europe, with interest in carbohydrate analysis and structure; carbohydrates in medicine and glycopathology; structure, function, application, and protein engineering of carbohydrate active enzymes; oligo- and polysaccharides of industrial interest; and production of carbohydrate containing new materials.The first chapters address glycoconjugates as modulatory and recognition molecules, structure determination using NMR and mass spectrometry, and microdialysis-chip enzyme-based sensors. Active site mutations coupled with crystal structures and synthetic substrate analogue interactions as well as new three-dimensional structures and binding domains for biotechnological applications are included in the chapters. Carbohydrate active enzymes turned out to be a predominant topic.The rapid development in glycobiology and glycotechnology has resulted in an enormous increase in our knowledge on the structure conversion, and application of carbohydrates in industry and medicine.
Author(s): Steffen B. Petersen, Birte Svensson and Sven Pedersen (Eds.)
Series: Progress in Biotechnology 10
Edition: 1
Publisher: Elsevier, Academic Press
Year: 1995
Language: English
Pages: 1-369
Content:
Preface
Pages v-vi
Sven Pedersen, Steffen B. Petersen, Birte Svensson
Glycans of glycoconjugates as modulatory and recognition molecules Original Research Article
Pages 1-13
Nathan Sharon
NMR studies of the structure and dynamics of carbohydrates in aqueous solution Original Research Article
Pages 15-28
Herman van Halbeek, Shuqun Sheng
Linkage analysis by mass spectrometry of chemically modified oligosaccharides from glycosphingolipids and glycoproteins Original Research Article
Pages 29-47
Bo Nilsson
Development of a novel enzyme based glucose sensor Original Research Article
Pages 49-58
F. Spener, R. Steinkuhl, C. Dumschat, H. Hinkers, K. Cammann, M. Knoll
Carbohydrate binding at the active site of Escherichia coli maltodextrin phosphorylase Original Research Article
Pages 59-69
P. Drueckes, D. Palm, R. Schinzel
The chitinolytic system of Streptomyces olivaceoviridis Original Research Article
Pages 71-75
H. Schrempf
Properties and production of the β-glycosidase from the thermophilic archaeon sulfolobus solfataricus expressed in mesophilic hosts Original Research Article
Pages 77-84
M. Moracci, L. Capalbo, M. De Rosa, R. La Montagna, A. Morana, R. Nucci, M. Ciaramella, M. Rossi
Contribution of subsites to catalysis and specificity in the extended binding cleft of Bacillus 1,3-1,4-β-D-glucan 4-glucanohydrolases Original Research Article
Pages 85-95
Antoni Planas, Carles Malet
Probing of glycosidase active sites through labeling, mutagenesis and kinetic studies Original Research Article
Pages 97-111
Stephen G. Withers
Thiooligosaccharides: toys or tools for the studies of Glycanases Original Research Article
Pages 113-124
H. Driguez
Mutational analysis of catalytic mechanism and specificity in amylolytic enzymes Original Research Article
Pages 125-145
B. Svensson, T.P. Frandsen, I. Matsui, N. Juge, H.-P. Fierobe, B. Stoffer, K.W. Rodenburg
The structure and function relationship of Schizophyllum commune xylanase A Original Research Article
Pages 147-163
M.R. Bray, A.J. Clarke
Protein engineering of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 Original Research Article
Pages 165-174
L. Dijkhuizen, D. Penninga, H.J. Rozeboom, B. Strokopytov, B.W. Dijkstra
Oxidation stable amylases for detergents Original Research Article
Pages 175-179
Torben V. Borchert, Søren F. Lassen, Allan Svendsen, Henrik B. Frantzen
Electrostatic studies of carbohydrate active enzymes Original Research Article
Pages 181-204
Antonio Baptista, Trygve Brautaset, Finn Drabløs, Paulo Martel, Svein Valla, Steffen B. Petersen
Effects of glycosylation on protein folding, stability and solubility. Studies of chemically modified or engineered plant and fungal peroxidases Original Research Article
Pages 205-210
K.G. Welinder, J.W. Tams
Modes of action of two Trichoderma reesei cellobiohydrolases Original Research Article
Pages 211-224
Tuula T. Teeri, Anu Koivula, Markus Linder, Tapani Reinikainen, Laura Ruohonen, Malee Srisodsuk, Marc Claeyssens, T. Alwyn Jones
Structural studies on fungal endoglucanases from Humicola insolens Original Research Article
Pages 225-237
Gideon J. Davies, Martin Schülein
The catalytic domain of endoglucanase A from Clostridium cellulolyticum belonging to family 5: an α/β-barrel enzyme Original Research Article
Pages 239-250
V. Ducros, M. Czjzek, A. Belaich, C. Gaudin, R. Haser
Cellulosome domains for novel biotechnological application Original Research Article
Pages 251-259
Edward A. Bayer, Ely Morag, Meir Wilchek, Raphael Lamed, Sima Yaron, Yuval Shoham
Interactions of cellulases from Cellulomonas fimi with cellulose Original Research Article
Pages 261-270
N. Din, J.B. Coutinho, N.R. Gilkes, E. Jervis, D.G. Kilburn, R.C. Miller Jr., E. Ong, P. Tomme, R.A.J. Warren
Transgenic plants as a tool to understand starch biosynthesis Original Research Article
Pages 271-278
J. Koßmann, G. Abel, V. Büttcher, E. Duwenig, M. Emmermann, R. Lorberth, F. Springer, I. Virgin, T. Welsh, L. Willmitzer
Targeted expression of microbial cellulases in transgenic animals Original Research Article
Pages 279-293
Simi Ali, Judith Hall, Kathleen L. Soole, Carlos M.G.A. Fontes, Geoffrey P. Hazlewood, Barry H. Hirst, Harry J. Gilbert
Mechanism and action of glucansucrases Original Research Article
Pages 295-312
John F. Robyt
Studies on a recombinant amylosucrase Original Research Article
Pages 313-320
M. Remaud-Simeon, F. Albaret, B. Canard, I. Varlet, P. Colonna, R.M. Willemot, P. Monsan
Application of cloned monocomponent carbohydrases for modification of plant materials Original Research Article
Pages 321-342
L.V. Kofod, T.E. Mathiasen, H.P. Heldt-Hansen, H. Dalbøge
Fatty acid esters of ethyl glucoside, a unique class of surfactants Original Research Article
Pages 343-349
Otto Andresen, Ole Kirk
A wide range of carbohydrate modifications by a single micro-organism: leuconostoc mesenteroides Original Research Article
Pages 351-358
W. Soetaert, D. Schwengers, K. Buchholz, E.J. Vandamme
Index
Pages 359-369
