''Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles. The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including: Human T-cell leukemia virus type 1 (HTLV-1), Hepatitis C virus (HCV), Epstein-Barr virus (EBV), Human papilloma virus (HPV), Human herpes virus 8 (HHV-8)/Kaposi's sarcoma-associated herpes virus (KSHV), Human immunodeficiency virus (HIV/AIDS), Oncolytic viruses. This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies''--Provided by publisher. Read more...
Content: Chapter 1. Cancer-causing viruses : an introduction / Satya P. Gupta and Vertika Gautam --
chapter 2. Targeting human T-cell leukemia virus type 1 : pathogenesis and treatment strategies / Jun-ichirou Yasunaga --
chapter 3. Hepatitis C virus and its inhibitors : the polymerase as a target for nucleoside and nucleotide analogs / Jerome Deval and Martin Huber --
chapter 4. Mechanisms of Hepatitis C virus clearance by interferon and ribavirin combination : lessons learned from in vitro cell culture / Srikanta Dash, Partha K. Chandra, Kurt Ramazan, Robert F. Garry, and Luis A. Balart --
chapter 5. Hepatitis B virus infection and hepatocellular carcinoma / Rakhi Maiwall and Manoj Kumar Sharma --
chapter 6. Epstein-Barr virus and treatment of its infection / Tarun Jha, Amit Kumar Halder, and Nilanjan Adhikari --
chapter 7. Landscape of Papillomavirus in human cancers : prevention and therapeutic avenues / Susri Ray Chaudhuri (Guha), Anirban Roy, Indranil Chatterjee, Rahul Roy Chowdhury, and Snehasikta Swarnakar --
chapter 8. Role of high-risk human Papillomaviruses in breast carcinogenesis / Ala-Eddin Al Moustafa --
chapter 9. Prospective therapies of genital human Papillomavirus infections / Ricardo Ney Oliveira Cobucci, Janaina Cristiana de Oliveira Crispim, and Ana Katherine da Silveira Gonçalves --
chapter 10. Human Herpesvirus type 8/Kaposi Sarcoma Herpesvirus : an overview of viral pathogenesis and treatment of associated diseases / Hiba El Hajj, Raghida Abou Merhi, and Ali Bazarbachi --
chapter 11. Tea polyphenolic compounds against Herpes Simplex viruses / Tin-Chun Chu, Sandra D. Adams, and Lee H. Lee --
chapter 12. HIV integrase inhibitors : qualitative and quantitative structure : activity relationship studies / Rajni Garg and Gene M. Ko --
chapter 13. Virus wars : oncolytic versus oncogenic viruses / Markus Vähä-Koskela, Fabrice Le Boeuf, and Vincenzo Cerullo --
chapter 14. Oncolytic viruses and histone deacetylase inhibitors / Vaishali M. Patil and Satya P. Gupta.
Abstract: ''Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles. The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including: Human T-cell leukemia virus type 1 (HTLV-1), Hepatitis C virus (HCV), Epstein-Barr virus (EBV), Human papilloma virus (HPV), Human herpes virus 8 (HHV-8)/Kaposi's sarcoma-associated herpes virus (KSHV), Human immunodeficiency virus (HIV/AIDS), Oncolytic viruses. This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies''--Provided by publisher
