This volume highlights the remarkable new developments in brain imaging, including those that apply magnetic resonance imaging (MRI) and Positron Emission Tomography (PET), that allow us to non invasively study the living human brain in health and in disease. These technological advances have allowed us to obtain new and powerful insights into the structure and function of the healthy brain as it develops across the life cycle, as well as the molecular make up of brain systems and circuits as they develop and change with age. New brain imaging technologies have also given us new insights into the causes of many common brain disorders, including ADHD, schizophrenia, depression and Alzheimer’s disease, which collectively affect a large segment of the population. These new insights have major implications for understanding and treating these brain disorders, and are providing clinicians with the first ever set of biomarkers that can be used to guide diagnosis and monitor treatment effects. The advances in brain imaging over the last 20 years, summarized in this volume, represent a major advance in modern biomedical sciences.
Author(s): N. D. Volkow, G. J. Wang, J. S. Fowler (auth.), Cameron S. Carter, Jeffrey W. Dalley (eds.)
Series: Current Topics in Behavioral Neurosciences 11
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2012
Language: English
Pages: 394
Tags: Neurosciences; Imaging / Radiology; Nuclear Medicine
Front Matter....Pages i-x
Food and Drug Reward: Overlapping Circuits in Human Obesity and Addiction....Pages 1-24
Nonhuman Primate Models of Addiction and PET Imaging: Dopamine System Dysregulation....Pages 25-44
PET Applications in Animal Models of Neurodegenerative and Neuroinflammatory Disorders....Pages 45-64
Neural and Behavioral Endophenotypes in ADHD....Pages 65-91
Experimental Protocols for Behavioral Imaging: Seeing Animal Models of Drug Abuse in a New Light....Pages 93-115
Molecular Imaging and the Neuropathologies of Parkinson’s Disease....Pages 117-148
Imaging of Seasonal Affective Disorder and Seasonality Effects on Serotonin and Dopamine Function in the Human Brain....Pages 149-167
Magnetic Resonance Spectroscopic Methods for the Assessment of Metabolic Functions in the Diseased Brain....Pages 169-198
MR Spectroscopic Studies of the Brain in Psychiatric Disorders....Pages 199-251
fMRI as a Measure of Cognition Related Brain Circuitry in Schizophrenia....Pages 253-267
MRI Studies in Late-Life Mood Disorders....Pages 269-287
The Role of Diffusion Tensor Imaging in the Study of Cognitive Aging....Pages 289-320
Structural, Functional and Spectroscopic MRI Studies of Methamphetamine Addiction....Pages 321-364
Pharmacological MRI Approaches to Understanding Mechanisms of Drug Action....Pages 365-388
Back Matter....Pages 389-391
