For this edition of the book, the concept of brain-disabling treatment has been updated and expanded with the additional concept of medication spellbinding (intoxication anosognosia). The neuroleptic chapters have been updated to include much more material on the newer, atypical drugs, and well as new information on the neurotoxicity and cytotoxicity of all antipsychotic drugs. A massive amount of new information about antidepressant drugs and the stimulant drugs has resulted in an additional chapter on each drug.
The new edition concludes with two entirely new chapters on treatment--one on how to safely withdraw from psychiatric drugs and the other about psychosocial and educational approaches to very disturbed people, including 20 guidelines for therapy.