Biosurfactants: Research and Development provides a thorough overview of biosurfactant research and development across a range of settings and industries, highlighting the novel use of enzymes, metabolic and genetic engineering in biosurfactant production and showcasing diverse experimental models and approaches. Sections discuss fundamental characteristics of biosurfactants, their physio-chemical properties, and their differences from chemically synthesize surfactants, different research approaches for the study of known biosurfactants, and the genetic manipulation of microorganisms to increase biosurfactant productivity, or to produce molecules with improved characteristics.
Throughout the book, methods and approaches are discussed in easy-to-digest formats, with methods discussed, ranging from in silico approaches to classical biocatalysis omics analysis and metabolic engineering.
Author(s): Gloria Soberon-Chavez
Series: Foundations and Frontiers in Enzymology
Publisher: Academic Press
Year: 2023
Language: English
Pages: 307
City: London
Biosurfactants
Contributors
Copyright
Preface
Microbial bio-based amphiphiles (biosurfactants): General aspects on critical micelle concentration, surface t ...
Introduction
Biosurfactants in solution
Hydrophilic-lipophilic balance (HLB)
Surface tension (ST) and critical micelle concentration (CMC)
Surface tension and CMC data dispersion
Self-assembly and phase diagrams
Micelles in solution
The fiber phase
Membranes
Less common structures
Comments
Unique macroscale properties of biomphiphiles
References
New insights in biosurfactants research
Introduction
Novel and traditional BS and their producers revisited
Biocatalysis, chemical, and genetic engineering strategies in BS research
Novel applications of BS
Concluding remarks
References
Bioinspired glycolipids: Metals interactions and aqueous-source metal recovery technologies
Introduction
Glycolipids
Microbially produced glycolipids
Bioinspired glycolipids
Complexation of metals by rhamnolipid
Metal selectivity
Mechanism of interaction
Glycolipid-based mining of metals from aqueous sources
Aqueous resources for critical materials
Exploitable aqueous resources
Potential to meet critical materials demand
Approaches and technologies
Ion flotation
Micellar-enhanced ultrafiltration
Precipitation-based technologies
Environmental benefits of glycolipid-based aqueous mining
Rhamnolipid treatment of metal-contaminated groundwater: A case study of uranium in Arizona
Conclusion
References
Rhamnolipids-Has the promise come true?
Introduction
Rhamnolipids prospects in retrospect view
Exploitation of antibiotic activity
Applications in environmental remediation, petroleum, and related areas
Cosmetics, personal care, and household products
Food application
Rhamnolipid bioproduction
Conclusions
References
Biosurfactants as food additives: New trends and applications
Biosurfactants in food formulation
BS as emulsifiers
Food preservatives: BS as antimicrobial agents
Antioxidants
Use of BS in food processing
BS as antiadhesive and antibiofilm agents
BS as cleaning agents
Nanotechnology, food, and BS
BS in food nanotechnology
Concluding remarks
References
Novel approaches in the use of biosurfactants in the oil industry and environmental remediation
Introduction
Types of biosurfactants
Marine biosurfactant-producing bacteria
Pseudomonas
Bacillus
Acinetobacter
Antarctobacter
Rhodococcus
Halomonas
Alcanivorax
Pseudoalteromonas
Marinobacter
Current exploitation of biosurfactants in the oil industry
Soil bioremediation
Microbial enhanced oil recovery (MEOR)
Marine oil spill response
Recent trends in the development of bio-based dispersants to combat marine oils spills
Conclusion and perspectives
References
Biosurfactants produced from corn steep liquor and other nonconventional sources: Their application in differe ...
Introduction
Use of naturally produced biosurfactants from CSL in different industries
Environmental applications
Nanotechnology applications
Cosmetic, pharmaceutical, and personal care applications
Agrochemical applications
Food applications
Use of other nonconventional sources to produce biosurfactants
Dairy industrial wastes
Fruit and vegetable wastes
Starch-rich wastes
Lignocellulosic wastes
Oily and glycerol-based wastes
Concluding remarks
Acknowledgment
References
Metabolic and process engineering on the edge-Rhamnolipids are a true challenge: A review
Introduction
Design of an optimal expression cassette
Biosynthetic genes
Promoter
Untranslated regions and translation initiation
Accessory genes
Integration concepts: Genome-based vs plasmid-based expression
Development of an enhanced chassis cell
Enhancing precursor-availability
Reduction of by-product formation and observed metabolic burden
Accessibility of uncommon substrates
Strain engineering for improved process control
Alternative genetic targets for improved RL synthesis
Fermentation of P. putida for production of RL
Cultivation strategies
Design considerations and hardware concepts
Dispersion and mixing
Preventing and disrupting foam formation
Design of foam-free production processes
Considerations for future bioeconomical-technical substrates
Bioreactor-coupled integrated downstream processing
Foam fractionation concepts
Purification based on micelle-forming properties
Concluding remarks
Acknowledgments
References
Improved production of novel (bola) glycolipid biosurfactants with the yeast Starmerella bombicola through an ...
Introduction
Diversifying and boosting glycolipid production with S. bombicola
Application of integrated -omics strategies for improved glycolipid biosynthesis with S. bombicola
A multiomics approach in industrial biotechnology: A work in progress
Case studies in omics integration in glycolipid production
Omics development in microbial fermentations and future perspectives
Acknowledgments and funding
References
Increasing the natural biodiversity of microbial lipopeptides using a synthetic biology approach
High natural biodiversity of lipopeptides
Bacterial lipopeptides
Lipopeptides produced by Bacillales
Bacillus-related lipopeptides
Surfactin
Iturin
Fengycin
Kurstakin
Other lipopeptides from Bacillus sp
Paenibacillus-related lipopeptides
Brevibacillus-related lipopeptides
Other lipopeptides produced by Bacillales
Actinobacteria-related lipopeptides
Pseudomonas-related lipopeptides
Pseudofactin
Viscosin
Orfamide
Amphisin
Putisolvin
Entolysin
Xantolysin
Tolaasin
Syringomycin
Syringopeptin 22
Syringopeptin 25
Syringafactin
Burkholderiales-related lipopeptides
Serratia-related lipopeptides
Serrawettin
Stephensiolide
Cyanobacteria-related lipopeptides
Other bacterial lipopeptides
Eukaryotic lipopeptides
Yeast and fungi-related lipopeptides
Animal-related lipopeptide
Uncharacterized biosurfactant lipopeptides
Production of novel lipopeptides
Change in the composition of amino acids
Precursor directed biosynthesis
Substrate recognition domain
Domain and module exchange
Altering the number of monomers
Altering monomer connectivity
Tailoring enzyme-Change conformation
Remodeling/assembling of biosynthetic gene clusters
Structure modification by modification of the FA moiety
Improving the homologous production of lipopeptides
Targeting gene regulation
Increase in transcription
Targeting the FA metabolism
Targeting the amino acid metabolism
Targeting the genome
Increase in transporters and toxicity resistance genes
Degradation
Heterologous production
Deciphering the complete biosynthesis mechanism
Choice of the host strain
Cloning strategy
Conclusion
Funding
References
Synthetic approaches to production of rhamnolipid and related glycolipids
Introduction
Rhamnolipids-Biosynthetic versus chemically synthesized
Congener distribution
Stereochemistry
Purity
Tailorability
Chemical synthesis of rhamnolipids
Commercialization of glycolipid synthesis
Performance of synthetic glycolipids
Conclusion
References
The use of biocatalysis for biosurfactant production
Introduction
Glycosyl hydrolases and/or glycosyl transferases
Reverse hydrolysis reaction (condensation)
Transglycosidation
Lipases
Glycolipids surfactants
N-acylation of amino acids
Proteases
Factors affecting the enzymatic production of biosurfactants
The nature of biocatalyst
The reactions media
Substrate ratio
Time of reaction
The immobilization of enzymes
Conclusions
Acknowledgments
References
Challenges and prospects for microbial biosurfactant research
Biosurfactants represent much more than environmental-friendly alternatives for chemical surfactants
Synthetic biology and omics approaches in biosurfactants research
Novel approaches for the sustainable production of biosurfactants
Bioinspired surfactants
Concluding remarks
References
