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Bioorganic Chemistry of Biological Signal Transduction

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A. Levitzki: Protein Tyrosine Kinase Inhibitors As Therapeutic Agents.- G. Müller: Peptiddomimetic SH2 Domain Antagonists for Targeting Signal Transduction.- J. Kuhlmann and C. Herrmann: Biophysical Characterisation of the Ras Protein.- H. Waldmann and M. Thutewohl: Ras-Farnesyltransferase-Inhibitors As Promising Anti-Tumor Drugs.- P.J. Hergenrother and S.F. Martin: Phosphatidylcholine-Preferring Phospholipase C from B. cereus. Function, Structure and Mechanism.- G. Dormán: Photoaffinity Labeling in Biological Signal Transduction.

Author(s): Alexander Levitzki (auth.), Prof. Dr. Herbert Waldmann (eds.)
Series: Topics in Current Chemistry 211
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2001

Language: English
Pages: 230
City: Berlin ; New York
Tags: Organic Chemistry;Biochemistry, general;Biophysics/Biomedical Physics

Protein Tyrosine Kinase Inhibitors as Therapeutic Agents....Pages 1-15
Peptidomimetic SH2 Domain Antagonists for Targeting Signal Transduction....Pages 17-59
Biophysical Characterization of the Ras Protein....Pages 61-116
Ras-Farnesyltransferase-Inhibitors as Promising Anti-Tumor Drugs....Pages 117-130
Phosphatidylcholine-Preferring Phospholipase C from B. cereus . Function, Structure, and Mechanism....Pages 131-167
Photoaffinity Labeling in Biological Signal Transduction....Pages 169-225