Open publication Biological systems have always inspired mankind in the creation of new systems and technologies. In recent years the interfaces between the biological and non-biological worlds appear increasingly blurred due to significant advances both in our understanding of biological phenomena, as well as the development of sophisticated means to manipulate biological systems for varied applications. Biomimetics as a discipline shows how biology and biological processes are manifested in diverse aspects of chemistry, physics and engineering. This book aims to methodically describe artificial and synthetic assemblies mimicking biological and living systems - from drug discovery to microelectronics and computer sciences.
Author(s): Raz Jelinek
Series: De Gruyter Graduate
Publisher: de Gruyter
Year: 2013
Language: English
Pages: vi+252
Biomimetics: A Molecular Perspective......Page 4
Contents......Page 6
1 Introduction......Page 8
2.1 Biomimetic functional materials......Page 10
2.2 Protein-based functional materials......Page 14
2.3 Bioelectronics......Page 33
2.4 Microorganism-synthesized biomimetic materials......Page 36
3.1 Adhesion and wetting......Page 46
3.2 Color and photonics......Page 55
3.3 Biosensing......Page 58
3.4 Cell-surface interactions......Page 59
4.1 Artificial organs......Page 68
4.2 Tissue engineering......Page 70
4.2.1 Cell seeding and growth in engineered tissues......Page 71
4.2.2 TE scaffolds......Page 72
4.2.3 Tissue-engineered cartilage: a case study......Page 89
4.3 Tissue engineering and drug design......Page 93
5 Biomineralization......Page 98
5.1 Protein- and peptide-associated biomineralization......Page 99
5.2 Organism-templated biomineralization......Page 109
6 Synthetic biology......Page 122
6.1 Synthetic proteins......Page 123
6.2 Directed evolution......Page 131
6.3 Protein modeling and synthetic proteins......Page 136
6.4 Engineered oligonucleotides and synthetic genes......Page 143
6.5 Synthetic functional biomolecules......Page 147
6.6 Artificial chromosomes......Page 150
6.7 Engineered microorganisms......Page 153
7 Artificial cells......Page 156
7.1 Biomimetic membranes......Page 157
7.2 Artificial cell division......Page 167
7.3 Biomolecules encapsulated in artificial cells......Page 170
7.4 Artificial replication......Page 172
8 Drug delivery......Page 178
9.1 Basics of DNA nanostructures......Page 198
9.2 DNA origami......Page 200
9.3 DNA-based advanced materials......Page 208
9.4 RNA nanostructures......Page 215
9.5 DNA-based computing......Page 218
10.1 Catalytic antibodies......Page 222
10.2 Artificial photosynthesis......Page 224
10.3 Bio-inspired motors......Page 228
10.4 Artificial muscles......Page 231
10.5 Biomimetic pores and channels......Page 235
10.6 Biomimetic signaling pathways......Page 238
10.7 Electronic noses......Page 239
10.8 Neural networks and biologically-inspired computers......Page 245
Further Reading......Page 252
Index......Page 256
