Biomechanics of the Gravid Human Uterus

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The complexity of human uterine function and regulation is one of the great wonders of nature and represents a daunting challenge to unravel. This book is dedicated to the biomechanical modeling of the gravid human uterus and gives an example of the application of the mechanics of solids and the theory of soft shells to explore medical problems of labor and delivery. After a brief overview of the anatomy, physiology and biomechanics of the uterus, the authors focus mainly on electromechanical wave processes, their origin, dynamics, and neuroendocrine and pharmacological modulations. In the last chapter applications, pitfalls and problems related to modeling and computer simulations of the pregnant uterus and pelvic floor structures are discussed. A collection of exercises is added at the end of each chapter to help readers with self-evaluation.

The book serves as an invaluable source of information for researchers, instructors and advanced undergraduate and graduate students interested in systems biology, applied mathematics and biomedical engineering.

Author(s): Roustem N. Miftahof, Hong Gil Nam (auth.)
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2011

Language: English
Pages: 179
Tags: Computer Appl. in Life Sciences; Human Physiology; Physiological, Cellular and Medical Topics; Systems Biology; Computational Biology/Bioinformatics

Front Matter....Pages i-xviii
Biological Preliminaries....Pages 1-14
Models of the Gravid Uterus....Pages 15-27
A Dynamic Model of the Fasciculus....Pages 29-50
General Theory of Thin Shells....Pages 51-64
Essentials of the Theory of Soft Shells....Pages 65-83
Continual Model of the Myometrium....Pages 85-96
Models of Synaptic Transmission and Regulation....Pages 97-116
Pharmacology of Myometrial Contractility....Pages 117-128
Gravid Uterus as a Soft Biological Shell....Pages 129-154
Biomechanics of the Gravid Uterus in Perspective....Pages 155-162
Back Matter....Pages 163-179