This book is essential reading for those interested in understanding current trends of research in the area of biomechanics at micro- and nanoscale levels. It details the research carried out to date in this field by fourteen prominent researchers as part of a four-year government supported project which commenced in 2003. It consists of four chapters entitled Cell Mechanics, Cell Response to Mechanical Stimulation, Tissue Engineering and Computational Biomechanics.
Author(s): Hiroshi Wada
Publisher: World Scientific
Year: 2005
Language: English
Pages: 178
City: Singapore; Hackensack, NJ
Tags: Специальные дисциплины;Наноматериалы и нанотехнологии;Нанобиотехнология;
CONTENTS ......Page 8
PREFACE ......Page 6
I. CELL MECHANICS ......Page 10
Heterogeneous expression of the motor protein prestin of cochlear outer hair cells ......Page 12
Effects of actin filaments on anisotropy and stiffness of aortic smooth muscle cells ......Page 25
Micro-vessel network formation of endothelial cells with in vitro three dimensional model ......Page 35
Time-dependent mechanical behaviors of articular cartilage and chondrocytes under constant total compressive deformation ......Page 46
II. CELL RESPONSE TO MECHANICAL STIMULATION ......Page 58
Threshold fiber strain that induces reorganization of cytoskeletal actin structure in osteoblastic cells ......Page 60
Morphology of endothelical cells in response to hydrostatic pressure ......Page 71
Mechanosensing in intestinal villi: ATP signaling in subepithelial fibroblasts network ......Page 81
III. TISSUE ENGINEERING ......Page 94
Microelements for cartilage tissue engineering ......Page 96
Interrelationship between water filtration velocity and the thickness of pseudointima formed at the wall of artificial vascular grafts implanted in the dog common carotid artery ......Page 105
Strengthening of fibrous tissues under mechanical stimuli ......Page 117
IV. COMPUTATIONAL BIOMECHANICS ......Page 128
Assessment of cortical bone microstructure using monochromatic synchrotron radiation micro-CT ......Page 130
Study on particle presentations of blood cells and the plasma in microvascular blood flow ......Page 141
Brief reviews of mechanical models of skeletal muscle and formulation of a muscle model taking into account microstructure and damage ......Page 150
Numerical simulation of the effects of actin binding and cellular deformation on the orientation of actin stress fibers under cyclic stretch ......Page 158
SUBJECT INDEX ......Page 170
