Biological Resource Centers: Knowledge Hubs for the Life Sciences

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Biological resource centres (BRCs) collect, certify and distribute organisms for use in research and in the development of commerical products in the pharmaceutical, agricultural and biotechnology industries. They maintain a large and varied collection, including cell lines, micro-organisms, recombinant DNA material, biological media and reagents, and the information technology tools that allow researchers to access biological materials. BRCs have established themselves as a crucial element in the life science innovation infrastructure, from their early impact on virology to their crucial role in addressing cross-culture contamination in the 1970s to their current leadership in promoting a global biodiversity network. They confront new challenges, resulting from shifts in the nature of biological research, the interaction between public and private researchers and the increasing focus on biosecurity. This volume offers a systematic economic assessment of the impact of biological resource centres through their role in facilitating cumulative knowledge in the life sciences and building on their roles as knowledge hubs - institutions that facilitate the transfer of scientific and technical knowledge among members of a research community. The knowledge hubs framework offers insight into how to develop and evaluate policy proposals that impinge on the control and access of biological materials. Stern argues that science and innovation policy must be premised on a clear understanding of the role that knowledge hubs play and the policy mechanisms that encourage their sustained growth and effectiveness.

Author(s): Scott Stern
Publisher: Brookings Institution Press
Year: 2004

Language: English
Pages: 128

Cover......Page 1
Title Page......Page 4
Contents......Page 6
Acknowledgments......Page 8
1. Introduction......Page 12
2. Evolution and Adaptation: A Short History of Biological Resource Centers......Page 20
3. Climbing atop the Shoulders of Giants: BRCs as Cumulative Knowledge Hubs......Page 47
4. A Penny for Your Quotes? The Impact of BRCs on Life Sciences Research......Page 67
5. Policy Challenges and Principles: Implications for BRC Stakeholders......Page 87
6. Future Challenges......Page 116
Appendix A: Econometric Results......Page 121
Appendix B: Biological Resource Centers: Policy Implications for Stakeholder Communities......Page 125
References......Page 128
Index......Page 134