This volume constitutes the refereed proceedings of the 7th International Symposium on Bioinformatics Research and Applications, ISBRA 2011, held in Changsha, China, in May 2011. The 36 revised full papers presented together with 4 invited talks were carefully reviewed and selected from 92 submissions. Topics presented span all areas of bioinformatics and computational biology, including the development of experimental or commercial systems.
Author(s): Russell Schwartz (auth.), Jianer Chen, Jianxin Wang, Alexander Zelikovsky (eds.)
Series: Lecture Notes in Computer Science 6674
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2011
Language: English
Pages: 454
Tags: Computational Biology/Bioinformatics; Data Mining and Knowledge Discovery; Information Systems Applications (incl.Internet); Algorithm Analysis and Problem Complexity; Pattern Recognition; Computer Appl. in Life Sciences
Front Matter....Pages -
Phylogenetics of Heterogeneous Samples....Pages 1-1
OMG! Orthologs for Multiple Genomes - Competing Formulations....Pages 2-3
Phylogenetic Analysis of Whole Genomes....Pages 4-7
Genetic and Pharmacogenetic Studies of Neuropsychiatric Disorders: Increasingly Critical Roles of Bioinformatics Research and Applications....Pages 8-10
Genome-Phenome Association Analysis of Complex Diseases a Structured Sparse Regression Approach....Pages 11-11
Prediction of Essential Proteins by Integration of PPI Network Topology and Protein Complexes Information....Pages 12-24
Computing the Protein Binding Sites....Pages 25-36
SETTER - RNA SEcondary sTructure-based TERtiary Structure Similarity Algorithm....Pages 37-48
Prediction of Essential Genes by Mining Gene Ontology Semantics....Pages 49-60
High-Performance Blob-Based Iterative Reconstruction of Electron Tomography on Multi-GPUs....Pages 61-72
Component-Based Matching for Multiple Interacting RNA Sequences....Pages 73-86
A New Method for Identifying Essential Proteins Based on Edge Clustering Coefficient....Pages 87-98
Gene Order in Rosid Phylogeny, Inferred from Pairwise Syntenies among Extant Genomes....Pages 99-110
Algorithms to Detect Multiprotein Modularity Conserved during Evolution....Pages 111-122
The Kernel of Maximum Agreement Subtrees....Pages 123-135
A Consensus Approach to Predicting Protein Contact Map via Logistic Regression....Pages 136-147
A Linear Time Algorithm for Error-Corrected Reconciliation of Unrooted Gene Trees....Pages 148-159
Comprehensive Pharmacogenomic Pathway Screening by Data Assimilation....Pages 160-171
The Deep Coalescence Consensus Tree Problem is Pareto on Clusters....Pages 172-183
Fast Local Search for Unrooted Robinson-Foulds Supertrees....Pages 184-196
A Metric for Phylogenetic Trees Based on Matching....Pages 197-208
Describing the Orthology Signal in a PPI Network at a Functional, Complex Level....Pages 209-226
Algorithms for Rapid Error Correction for the Gene Duplication Problem....Pages 227-239
TransDomain: A Transitive Domain-Based Method in Protein–Protein Interaction Prediction....Pages 240-252
Rapid and Accurate Generation of Peptide Sequence Tags with a Graph Search Approach....Pages 253-261
In Silico Evolution of Multi-scale Microbial Systems in the Presence of Mobile Genetic Elements and Horizontal Gene Transfer....Pages 262-273
Comparative Evaluation of Set-Level Techniques in Microarray Classification....Pages 274-285
Gene Network Modules-Based Liner Discriminant Analysis of Microarray Gene Expression Data....Pages 286-296
A Polynomial Algebra Method for Computing Exemplar Breakpoint Distance....Pages 297-305
The Maximum Clique Enumeration Problem: Algorithms, Applications and Implementations....Pages 306-319
Query-Adaptive Ranking with Support Vector Machines for Protein Homology Prediction....Pages 320-331
A Novel Core-Attachment Based Greedy Search Method for Mining Functional Modules in Protein Interaction Networks....Pages 332-343
ProPhyC: A Probabilistic Phylogenetic Model for Refining Regulatory Networks....Pages 344-357
Prediction of DNA-Binding Propensity of Proteins by the Ball-Histogram Method....Pages 358-367
Multi-label Correlated Semi-supervised Learning for Protein Function Prediction....Pages 368-379
Regene: Automatic Construction of a Multiple Component Dirichlet Mixture Priors Covariance Model to Identify Non-coding RNA....Pages 380-391
Accurate Estimation of Gene Expression Levels from DGE Sequencing Data....Pages 392-403
An Integrative Approach for Genomic Island Prediction in Prokaryotic Genomes....Pages 404-415
A Systematic Comparison of Genome Scale Clustering Algorithms....Pages 416-427
Mining Biological Interaction Networks Using Weighted Quasi-Bicliques....Pages 428-439
Towards a Characterisation of the Generalised Cladistic Character Compatibility Problem for Non-branching Character Trees....Pages 440-451
Back Matter....Pages -
