This volume constitutes the refereed proceedings of the 6th International Symposium on Bioinformatics Research and Applications, ISBRA 2010, held in Storrs, CT, USA, in May 2010. The 20 revised full papers and 6 invited talks presented were carefully reviewed and selected out of 57 submissions. Topics presented span all areas of bioinformatics and computational biology, including the development of experimental or commercial systems.
Author(s): Catalin Barbacioru (auth.), Mark Borodovsky, Johann Peter Gogarten, Teresa M. Przytycka, Sanguthevar Rajasekaran (eds.)
Series: Lecture Notes in Computer Science 6053 : Lecture Notes in Bioinformatics
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2010
Language: English
Pages: 253
Tags: Database Management; Information Systems Applications (incl.Internet); Information Storage and Retrieval; Algorithm Analysis and Problem Complexity; Data Mining and Knowledge Discovery; Pattern Recognition
Front Matter....Pages -
Tracing the Early Cell Divisions of Mouse Embryos by Single Cell RNA-Seq....Pages 1-1
Successes and Failures of Elegant Algorithms in Computational Biology....Pages 2-2
Modeling without Borders: Creating and Annotating VCell Models Using the Web....Pages 3-17
Touring Protein Space with Matt....Pages 18-28
Fixed-Parameter Algorithm for General Pedigrees with a Single Pair of Sites....Pages 29-37
Analysis of Temporal-spatial Co-variation within Gene Expression Microarray Data in an Organogenesis Model....Pages 38-49
Human Genome Annotation....Pages 50-51
Extensions and Improvements to the Chordal Graph Approach to the Multi-state Perfect Phylogeny Problem....Pages 52-60
Analysis of Gene Interactions Using Restricted Boolean Networks and Time-Series Data....Pages 61-76
Residue Contexts: Non-sequential Protein Structure Alignment Using Structural and Biochemical Features....Pages 77-88
Essential Proteins Discovery from Weighted Protein Interaction Networks....Pages 89-100
Identifying Differentially Abundant Metabolic Pathways in Metagenomic Datasets....Pages 101-112
A Novel Approach for Compressing Phylogenetic Trees....Pages 113-124
Structure of Proximal and Distant Regulatory Elements in the Human Genome....Pages 125-125
Combinatorics in Recombinational Population Genomics....Pages 126-127
Uncovering Hidden Phylogenetic Consensus....Pages 128-139
An Agglomerate Algorithm for Mining Overlapping and Hierarchical Functional Modules in Protein Interaction Networks....Pages 140-151
Fast Protein Structure Alignment....Pages 152-165
Predicting and Analyzing Cellular Networks....Pages 166-166
A Consensus Tree Approach for Reconstructing Human Evolutionary History and Detecting Population Substructure....Pages 167-178
Inferring Evolutionary Scenarios for Protein Domain Compositions....Pages 179-190
Local Structural Alignment of RNA with Affine Gap Model....Pages 191-202
Fast Computation of the Exact Hybridization Number of Two Phylogenetic Trees....Pages 203-214
“Master-Slave” Biological Network Alignment....Pages 215-229
Deciphering Transcription Factor Binding Patterns from Genome-Wide High Density ChIP-chip Tiling Array Data....Pages 230-240
The Expected Fitness Cost of a Mutation Fixation under the One-Dimensional Fisher Model....Pages 241-252
Back Matter....Pages -
