Bioinformatics: German Conference on Bioinformatics, GCB'96 Leipzig, Germany September 30 – October 2, 1996 Selected Papers

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This book constitutes the strictly refereed post-workshop proceedings of the German Conference on Bioinformatics, GCB'96, held in Leipzig, Germany, in September/October 1996. The volume presents 18 revised full papers together with three invited papers; these contributions were selected after a second round of reviewing from the 91 conference presentations. The book addresses current issues in computational biology and biologically inspired computing. The papers are organized in sections on biological and metabolic pathways, sequence analysis, molecular modeling, visualization, and formal languages, and DNA.

Author(s): Michael Conrad, Klaus-Peter Zauner (auth.), Ralf Hofestädt, Thomas Lengauer, Markus Löffler, Dietmar Schomburg (eds.)
Series: Lecture Notes in Computer Science 1278
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 1997

Language: English
Pages: 228
Tags: Theory of Computation; Simulation and Modeling; Computer Appl. in Life Sciences; Molecular Medicine

Molecular computing: From conformational pattern recognition to complex processing networks....Pages 1-10
A look at the visual modeling of plants using L-systems....Pages 11-29
Bioinformatics and cheminformatics in the drug discovery cycle....Pages 30-43
New developments in linking of biological databases and computer-generation of annotation: SWISS-PROT and its computer-annotated supplement TREMBL....Pages 44-51
EpoDB: An erythropoiesis gene expression database in progress....Pages 52-61
Recent advances in molecular distance geometry....Pages 62-71
Three models of gene regulation in E. coli ....Pages 72-78
A new method to develop highly specific models for regulatory DNA regions....Pages 79-87
Towards an object-oriented framework for the modeling of integrated metabolic processes....Pages 88-98
TRRD and COMPEL databases on transcription linked to TRANSFACAS as tools for analysis and recognition of regulatory sequences....Pages 99-105
Integrating heterogeneous datasets in genomic mapping: Radiation hybrids, YACs, genes and STS markers over the entire human chromosome X....Pages 106-114
A clustering approach to Generalized Tree Alignment with application to Alu repeats....Pages 115-124
Simple folding model for HP lattice proteins....Pages 125-136
Fast protein fold recognition and accurate sequence-structure alignment....Pages 137-146
Carbohydrates: Second-class citizens in biomedicine and in bioinformatics?....Pages 147-155
Structural constraints and neutrality in RNA....Pages 156-165
A systematic approach to finding new lead structures having biological activity....Pages 166-177
Visualization and analysis of the complete yeast genome....Pages 178-188
Virtual reality modeling for structural biology....Pages 189-198
Evolutionary grammars: A grammatical model for genome evolution....Pages 199-209
From DNA recombination to DNA computing via formal languages....Pages 210-220