This comprehensive textbook presents a self-contained guide to bioinformatics, defined in its broadest sense as the application of information science to biology. Thoroughly updated and greatly expanded, this third edition now includes material on the growing array of “-omics”; covering metagenomics, toxicogenomics, glycomics, lipidomics, microbiomics and phenomics. New chapters have also been added on ecosystems management and the nervous system. Emphasis is placed on providing both a firm grounding in the core concepts and a clear overview of the complete field of bioinformatics. Features: explains the fundamentals of information science relevant to biology; covers both organismal (ontogeny and phylogeny, as well as genome structure) and molecular aspects; examines the most important practical applications of bioinformatics, providing detailed descriptions of both the experimental process and the data analysis; provides a varied selection of problems throughout the book, to stimulate further thinking.
Author(s): Jeremy Ramsden (auth.)
Series: Computational Biology 21
Edition: 3
Publisher: Springer-Verlag London
Year: 2015
Language: English
Pages: 308
Tags: Computational Biology/Bioinformatics; Cell Biology; Bioinformatics; Computer Appl. in Life Sciences; Biophysics and Biological Physics; Systems Theory, Control
Front Matter....Pages i-xix
Introduction....Pages 1-6
Front Matter....Pages 7-7
The Nature of Information....Pages 9-31
The Transmission of Information....Pages 33-48
Sets and Combinatorics....Pages 49-53
Probability and Likelihood....Pages 55-69
Randomness and Complexity....Pages 71-84
Systems, Networks, and Circuits....Pages 85-99
Algorithms....Pages 101-113
Front Matter....Pages 115-115
Introduction to Part II....Pages 117-128
The Nature of Living Things....Pages 129-174
The Molecules of Life....Pages 175-194
Front Matter....Pages 195-195
Introduction to Part III....Pages 197-201
Genomics....Pages 203-221
Proteomics....Pages 223-239
The Glycome, Lipidome and Microbiome....Pages 241-242
Interactomics: Interactions and Regulatory Networks....Pages 243-260
The Nervous System....Pages 261-264
Metabolomics and Metabonomics....Pages 265-270
Phenomics....Pages 271-274
Medical Applications....Pages 275-286
Front Matter....Pages 195-195
Ecosystems Management....Pages 287-289
The Organization of Knowledge....Pages 291-298
Back Matter....Pages 299-308
