Research on the biochemistry and molecular biology of lipids and lipoproteins has experienced remarkable growth in the last 20 years, particularly with the realization that many different classes of lipids play fundamental roles in diseases such as heart disease, obesity, diabetes, cancer and neurodegenerative disorders. The 5th edition of this book has been written with two major objectives. The first objective is to provide students and teachers with an advanced up-to-date textbook covering the major areas of current interest in the lipid field. The chapters are written for students and researchers familiar with the general concepts of lipid metabolism but who wish to expand their knowledge in this area. The second objective is to provide a reference text for scientists who are about to enter the field of lipids, lipoproteins and membranes and who wish to learn more about this area of research. All of the chapters have been extensively updated since the 4th edition appeared in 2002.
Key Features:
* Represents a bridge between the superficial coverage of the lipid field found in basic biochemistry text books and the highly specialized material contained in scientific review articles and monographs.
* Allows scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances.
* Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry.
Author(s): Dennis E. Vance and Jean E. Vance (Eds.)
Series: New Comprehensive Biochemistry 31
Edition: 5
Publisher: Elsevier Science
Year: 1996
Language: English
Commentary: +OCR
Pages: iii-viii, 1-553
Content:
Edited by
Page iii
Copyright page
Page iv
Preface
Page v
Dennis Vance, Jean Vance
List of contributors
Pages vii-viii
Chapter 1 Physical properties and functional roles of lipids in membranes Original Research Article
Pages 1-33
Pieter R. Cullis, David B. Fenske, Michael J. Hope
Chapter 2 Lipid metabolism in prokaryotes Original Research Article
Pages 35-74
Charles O. Rock, Suzanne Jackowski, John E. Cronan
Chapter 3 Oxidation of fatty acids Original Research Article
Pages 75-99
Horst Schulz
Chapter 4 Fatty acid synthesis in eukaryotes Original Research Article
Pages 101-127
Lisa M. Salati, Alan G. Goodridge
Chapter 5 Fatty acid desaturation and chain elongation in eukaryotes Original Research Article
Pages 129-152
Harold W. Cook
Chapter 6 Glycerolipid biosynthesis in eukaryotes Original Research Article
Pages 153-181
Dennis E. Vance
Chapter 7 Ether-linked lipids and their bioactive species: occurrence, chemistry, metabolism, regulation, and function Original Research Article
Pages 183-210
Fred Snyder
Chapter 8 Phospholipases Original Research Article
Pages 211-236
Moseley Waite
Chapter 9 Glycerolipids in signal transduction Original Research Article
Pages 237-255
J. David Lambeth, Sung Ho Ryu
Chapter 10 Adipose tissue and lipid metabolism Original Research Article
Pages 257-281
David A. Bernlohr, Melanie A. Simpson
Chapter 11 The eicosanoids: cyclooxygenase, lipoxygenase, and epoxygenase pathways Original Research Article
Pages 283-308
William L. Smith, Frank A. Fitzpatrick
Chapter 12 Sphringolipids: metabolism and cell signalling Original Research Article
Pages 309-339
Alfred H. Merill Jr., Charles C. Sweeley
Chapter 13 Isoprenoids, sterols and bile acids Original Research Article
Pages 341-362
Peter A. Edwards, Roger Davis
Chapter 14 Lipid metabolism in plants Original Research Article
Pages 363-389
Katherine M. Schmid, John B. Ohlrogge
Chapter 15 Lipid assembly into cell membranes Original Research Article
Pages 391-423
Dennis R. Voelker
Chapter 16 Assembly of proteins into membranes Original Research Article
Pages 425-471
Reinhart A.F. Reithmeier
Chapter 17 Structure, assembly and secretion of lipoproteins Original Research Article
Pages 473-493
Roger A. Davis, Jean E. Vance
Chapter 18 Dynamics of lipoprotein transport in the human circulatory system Original Research Article
Pages 495-516
Phoebe E. Fielding, Christopher J. Fielding
Chapter 19 Removal of lipoproteins from plasma Original Research Article
Pages 517-541
Wolfgang J. Schneider
Subject Index
Pages 543-553
