About the Series:
Advances in Biochemistry in Heath and Disease presents state-of-the-art discussions in cutting-edge biochemical research, offering exciting developments that impact healthcare and disease research. Volumes in the series focus on cross-disciplinary biomedical research and examine various topics in biochemistry, cell biology, molecular biology, and biomedicine.
Biochemistry of Atherosclerosis
Sukhinder Kaur Cheema
Biochemistry of Atherosclerosis examines atherosclerosis in great detail, focusing on the risk of atherosclerosis, and the biochemical pathways involved. It provides a breadth of knowledge as well as new insights into a variety of topics relating to atherosclerosis from leading scientists around the world who are at the forefront of atherosclerosis research. Biochemistry of Atherosclerosis is essential reading for biomedical and clinical researchers.
Key topics:
- Hyperlipidaemia and Atherosclerosis
- Diabetes Induced Atherosclerosis
- Hypertension Induced Atherosclerosis
- Homocysteine Metabolism and Atherosclerosis
- Role of the Immune System in Atherosclerosis
- Role of Infectious Agents in Atherogenesis
- Dietary Management of Aherosclerosis
About the Editor:
Sukhinder Kaur Cheema is currently Associate Professor of Biochemistry and a CIHR (Canadian Institutes of Health Research) New Investigator at the Memorial University of Newfoundland. An expert in nutritional biochemistry, lipid metabolism and cardiovascular disease, she is cross appointed in Faculty of Medicine at the Memorial University of Newfoundland.
Author(s): Jim W. Burgess, Philip A. Sinclair, Christophe M. Chretien, Jonathon Boucher (auth.), Associate Professor Sukhinder Kaur Cheema (eds.)
Edition: 1
Publisher: Springer US
Year: 2006
Language: English
Pages: 572
Tags: Biochemistry, general; Cell Biology; Molecular Medicine; Developmental Biology; Cardiology
Front Matter....Pages 1-1
Reverse Cholesterol Transport....Pages 3-22
The Role of LCAT in Atherosclerosis....Pages 23-38
Howdy Partner: Apolipoprotein A-I-ABCA1 Interactions Mediating HDL Particle Formation....Pages 39-52
Role of the Scavenger Receptor Class B Type I in Lipoprotein Metabolism and Atherosclerosis: Insight from Genetically Altered Mice....Pages 53-69
The Role of Scavenger Receptors in Signaling, Inflammation and Atherosclerosis....Pages 70-91
ABC Transporters and Apolipoprotein E: Critical Players in Macrophage Cholesterol Efflux and Atherosclerosis....Pages 92-120
Provision of Lipids for Very Low-Density Lipoprotein Assembly....Pages 121-149
Oxidatively Modified Low-Density Lipoproteins and Thrombosis....Pages 150-167
The Clinical Significance of Small, Dense Low-Density Lipoproteins....Pages 168-185
Bile Acids: At the Crossroads of Sterol, Fat and Carbohydrate Metabolism....Pages 186-201
Front Matter....Pages 203-203
Lipoprotein Metabolism in Insulin-Resistant States....Pages 205-246
The Roles of Protein Glycation, Glycoxidation, and Advanced Glycation End-Product Formation in Diabetes-Induced Atherosclerosis....Pages 247-283
Molecular and Cellular Mechanisms by Which Diabetes Mellitus Promotes the Development of Atherosclerosis....Pages 284-304
Hypertension and Atherosclerosis: Advanced Glycation End Products—A Common Link....Pages 305-326
Front Matter....Pages 327-327
Homocysteine Metabolism....Pages 329-357
Role of Hyperhomocysteinemia in Atherosclerosis....Pages 358-379
Molecular and Biochemical Mechanisms of Hyperhomocysteinemia-Induced Cardiovascular Disorders....Pages 380-394
Front Matter....Pages 395-395
The Role of the Immune System in Atherosclerosis: Lessons Learned from Using Mouse Models of the Disease....Pages 397-412
The Role of Infectious Agents in Atherogenesis....Pages 413-434
Transplant Arteriopathy: Role of Nitric Oxide Synthase....Pages 435-454
Front Matter....Pages 395-395
Insights into the Molecular Mechanisms of Plaque Rupture and Thrombosis....Pages 455-472
Front Matter....Pages 473-473
Modification of Biochemical and Cellular Processes in the Development of Atherosclerosis by Red Wine....Pages 475-494
Endothelial Dysfunction and Atherosclerosis: Role of Dietary Fats....Pages 495-518
Oxidized LDL and Antioxidants in Atherosclerosis....Pages 519-541
Dietary Fatty Acids and Stroke....Pages 542-552
