Because of the wealth of new information generated by the scientific community during the last decade on the role of nutrition on cancer risk, this book provides a forum for presentation and discussion of recent scientific data and highlights a set of dietary recommendations. Bioactive Compounds and Cancer presents chapters that highlight laboratory and clinical findings on how selected nutrients function as signaling molecules and, as such, influence cellular behavior and cancer predisposition. This important compendium focuses on understanding the role of nutrition in cancer biology, the molecular action of bioactive food components and xenobiotics on cancer risk, the role of dietary components in cancer prevention and/or treatment, and nutrition education with the most up to date dietary recommendations that may reduce cancer risk. This volume will be of interest to specialized health professionals, clinicians, nurses, basic and clinical researchers, graduate students, and health officials of public and private organizations.
Author(s): Nadia Howlader MS, Sean F. Altekruse DVM, PHD, Brenda K. Edwards PHD (auth.), John A. Milner, Donato F. Romagnolo (eds.)
Series: Nutrition and Health
Edition: 1
Publisher: Humana Press
Year: 2010
Language: English
Pages: 882
Tags: Clinical Nutrition; Nutrition; Metabolic Diseases; Cancer Research; Primary Care Medicine
Front Matter....Pages i-xxx
Front Matter....Pages 1-1
Monitoring the Burden of Cancer in the United States....Pages 3-23
Cancer Biology and Nutrigenomics....Pages 25-43
Cellular Cancer Processes and Their Molecular Targets for Nutritional Preemption of Cancer....Pages 45-70
Nutrigenetics: The Relevance of Polymorphisms....Pages 71-99
Diet and Epigenetics....Pages 101-123
Nutrient Signaling – Protein Kinase to Transcriptional Activation....Pages 125-143
Front Matter....Pages 145-145
Dietary Energy Balance, Calorie Restriction, and Cancer Prevention....Pages 147-164
Fiber and Microbially Generated Active Components....Pages 165-180
Gut Microbiota, Probiotics, Prebiotics and Colorectal Cancer....Pages 181-193
Meats, Protein and Cancer....Pages 195-212
Saturated Fatty Acids and Cancer....Pages 213-233
Conjugated Linoleic Acid and Cancer....Pages 235-251
Cancer and n –3PUFAs: The Translation Initiation Connection....Pages 253-273
n -6 Polyunsaturated Fatty Acids and Cancer....Pages 275-307
Front Matter....Pages 309-309
Carotenoids....Pages 311-333
Vitamin A....Pages 335-356
Vitamin D and Cancer Chemoprevention....Pages 357-385
Folate....Pages 387-410
Selenium....Pages 411-448
Calcium and Cancer....Pages 449-468
Front Matter....Pages 309-309
Iron and Cancer....Pages 469-496
Zinc in Cancer Development and Prevention....Pages 497-531
Front Matter....Pages 533-533
Cruciferous Vegetables, Isothiocyanates, Indoles, and Cancer Prevention....Pages 535-566
Garlic and Cancer Prevention....Pages 567-588
Mammary and Prostate Cancer Chemoprevention and Mechanisms of Action of Resveratrol and Genistein in Rodent Models....Pages 589-611
Cancer Prevention by Catechins, Flavonols, and Procyanidins....Pages 613-631
Mechanisms of Action of Isoflavones in Cancer Prevention....Pages 633-670
The Anticarcinogenic Properties of Culinary Herbs and Spices....Pages 671-701
Cancer Prevention with Berries: Role of Anthocyanins....Pages 703-723
Pomegranate....Pages 725-734
Alcohol and Cancer: Biological Basis....Pages 735-760
Aryl Hydrocarbon Receptor-Mediated Carcinogenesis and Modulation by Dietary Xenobiotic and Natural Ligands....Pages 761-782
Opportunities and Challenges for Communicating Food and Health Relationships to American Consumers....Pages 783-796
Back Matter....Pages 797-828
