This book provides a unique overview on the most recent developments in initially diverse areas of behavioral genomic research that now start to intertwine to provide more detailed insights into the complex nature of behavior in health and disease. It focuses on our current understanding of genetic and epigenetic mechanisms of brain function and how they contribute to the complex formation of behavioral traits and psychiatric disorders. Readers experience diverse perspectives of the contributing authors starting from the genetic viewpoint and the effort to establish functional connection between genetic variants and behavioral phenotypes. Particular attention is given to the broad spectrum of epigenetic mechanisms and behavior.
The chapter 'Role of MicoRNAs in Anxiety and Anxiety-Related Disorders' is available open access under a CC BY 4.0 license at link.springer.com
Author(s): Elisabeth B. Binder, Torsten Klengel (eds.)
Series: Current Topics in Behavioral Neurosciences
Publisher: Springer
Year: 2019
Language: English
Pages: 259
City: Cham
Front Matter ....Pages i-vii
GWAS of Behavioral Traits (Divya Mehta, Darina Czamara)....Pages 1-34
Genetic Variation in Long-Range Enhancers (John F. Fullard, Samir Rahman, Panos Roussos)....Pages 35-50
DNA Methylation and Hydroxymethylation and Behavior (Sarah R. Rustad, Ligia A. Papale, Reid S. Alisch)....Pages 51-82
Social Environment and Epigenetics (Sarah M. Merrill, Nicole Gladish, Michael S. Kobor)....Pages 83-126
The Role of Dynamic Histone Modifications in Learning Behavior (Andre Fischer)....Pages 127-157
Disease Modeling of Neuropsychiatric Brain Disorders Using Human Stem Cell-Based Neural Models (Johanna Kaindl, Beate Winner)....Pages 159-183
Role of MicroRNAs in Anxiety and Anxiety-Related Disorders (Conor P. Murphy, Nicolas Singewald)....Pages 185-219
Transposable Elements (G. Guffanti, A. Bartlett, P. DeCrescenzo, F. Macciardi, R. Hunter)....Pages 221-246
Multi-, Inter-, and Transgenerational Effects of Drugs of Abuse on Behavior (Fair M. Vassoler, Anika M. Toorie, Elizabeth M. Byrnes)....Pages 247-258
Correction to: Role of MicroRNAs in Anxiety and Anxiety-Related Disorders (Conor P. Murphy, Nicolas Singewald)....Pages 259-259
