The book is part of a series on Current Topics in Behavioral Neurosciences, which has as its focus anxiety and its treatment. We have brought together a distinguished cadre of authors with the aim of covering a broad array of topics related to anxiety disorders, ranging from clinical diagnosis, epidemiology, preclinical neuroscience, and animal models to established and innovative therapeutic approaches. The book aims at bridging these disciplines to provide an update of literature relevant to understanding anxiety, its consequences, and its management. Following is a brief overview of the chapters and their content, meant to serve as a guide to navigating the book. The ?rst section covers clinical aspects of anxiety disorders. Joe Bienvenu and colleagues provide an incisive overview of diagnostic considerations in the anxiety disorders in which they emphasize the strengths and shortcomings of our current nosologic systems. This is followed by a review and update of the epidemiology of anxiety disorders by Ron Kessler and colleagues, which provides an authoritative survey of anxiety disorder incidence, prevalence, and risk factors. This is comp- mented by a comprehensive review of the literature on disorders that co-occur with anxiety disorders by Kathleen Merikangas and Sonja Alsemgeest Swanson. Their review highlights the tremendous comorbidity that occurs not only within the anxiety disorders, but also with other mental and physical health conditions.
Author(s): O. Joseph Bienvenu, Lisa A. Wuyek (auth.), Murray B. Stein, Thomas Steckler (eds.)
Series: Current Topics in Behavioral Neurosciences 2
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2010
Language: English
Pages: 350
Tags: Neurosciences; Psychiatry; Pharmacology/Toxicology
Front Matter....Pages i-xv
Anxiety Disorders Diagnosis: Some History and Controversies....Pages 3-19
Epidemiology of Anxiety Disorders....Pages 21-35
Comorbidity in Anxiety Disorders....Pages 37-59
Genetics....Pages 63-75
Neuroanatomy of Anxiety....Pages 77-96
Stress and the Neuroendocrinology of Anxiety Disorders....Pages 97-118
Animal Models of Anxiety and Anxiolytic Drug Action....Pages 121-160
Genetic Approaches to Modeling Anxiety in Animals....Pages 161-201
Behavioral Correlates of Anxiety....Pages 205-228
Challenging Anxiety: A Focus on the Specificity of Respiratory Symptoms....Pages 229-250
Functional Neuroanatomy of Anxiety: A Neural Circuit Perspective....Pages 251-277
Pharmacological Enhancement of Behavioral Therapy: Focus on Posttraumatic Stress Disorder....Pages 279-299
The Pharmacology of Anxiety....Pages 303-330
GABA A Receptor α2/α3 Subtype-Selective Modulators as Potential Nonsedating Anxiolytics....Pages 331-360
Antidepressant Treatment in Anxiety Disorders....Pages 361-390
Metabotropic Glutamate Receptors: Their Therapeutic Potential in Anxiety....Pages 391-413
Developing Small Molecule Nonpeptidergic Drugs for the Treatment of Anxiety Disorders: Is the Challenge Still Ahead?....Pages 415-428
Cannabinoids and Anxiety....Pages 429-450
Pharmacological Treatment of Generalized Anxiety Disorder....Pages 453-467
Pharmacologic Treatment of Panic Disorder....Pages 469-485
Pharmacotherapy of Social Anxiety Disorder....Pages 487-503
Pharmacotherapy of Post-Traumatic Stress Disorder....Pages 505-525
Pharmacological Treatment of Obsessive-Compulsive Disorder....Pages 527-543
Back Matter....Pages 545-554
