This book is a concise and well-illustrated review of the physics and biology of radiation therapy intended for radiation oncology residents, radiation therapists, dosimetrists, and physicists. It presents topics that are included on the Radiation Therapy Physics and Biology examinations and is designed with the intent of presenting information in an easily digestible format with maximum retention in mind. The inclusion of mnemonics, rules of thumb, and reader-friendly illustrations throughout the book help to make difficult concepts easier to grasp. Basic Radiotherapy Physics and Biology is a valuable reference for students and prospective students in every discipline of radiation oncology.
Author(s): David S. Chang, Foster D. Lasley, Indra J. Das, Marc S. Mendonca, Joseph R. Dynlacht (auth.)
Edition: 1
Publisher: Springer International Publishing
Year: 2014
Language: English
Pages: 348
Tags: Radiotherapy; Diagnostic Radiology
Front Matter....Pages i-xix
Front Matter....Pages 1-1
Atomic and Nuclear Structure....Pages 3-10
Radioactive Decay....Pages 11-21
Production and Properties of Radiation....Pages 23-34
Interactions of Electromagnetic Radiation with Matter....Pages 35-41
Interactions of Particulate Radiation with Matter....Pages 43-54
Quantification and Measurement of Dose....Pages 55-68
Characteristics of Photon Beams....Pages 69-76
Dosimetry of Photon Beams in Water....Pages 77-92
Dosimetry of Photon Beams in a Patient....Pages 93-109
Dosimetry of Electron Beams....Pages 111-123
Physics and Dosimetry of Brachytherapy....Pages 125-137
Advanced Treatment Planning for EBRT....Pages 139-150
Linac Quality Assurance....Pages 151-154
Radiation Protection and Safety....Pages 155-163
Quality Management Program....Pages 165-168
Special Topics: Hyperthermia and Computers....Pages 169-177
Front Matter....Pages 179-179
Molecular Biology and Signaling....Pages 181-189
Cancer Genetic and Molecular Characteristics....Pages 191-199
Molecular Mechanisms of DNA Damage and Repair....Pages 201-209
Cell Death and Survival Assays....Pages 211-219
Front Matter....Pages 179-179
Fractionated Radiation Survival Models....Pages 221-233
Oxygen Effect, Relative Biological Effectiveness and Linear Energy Transfer....Pages 235-240
Tumor Microenvironment....Pages 241-247
Cell and Tissue Kinetics....Pages 249-258
Acute Effects of Total Body Irradiation (TBI)....Pages 259-263
Normal Tissue Radiation Responses....Pages 265-275
Therapeutic Ratio....Pages 277-282
Combined Modality Therapy....Pages 283-289
Biology of Brachytherapy, Particle Therapy, and Alternative Radiation Modalities....Pages 291-296
Hyperthermia....Pages 297-301
Carcinogenesis and Heritable Effects....Pages 303-311
Radiation Effects in the Embryo and Fetus....Pages 313-316
Back Matter....Pages 317-348
