Prostate brachytherapy (transperineal interstitial implantation of the prostate with either permanent or temporary radioactive sources) has evolved into a sophisticated and definitive treatment modality, used either as monotherapy or in combination with external beam radiation therapy for the treatment of prostate cancer. This popular form of therapy is frequently integrated with neoadjuvant and/or concurrent androgen suppression therapy in the intermediate and advanced risk patient. This book covers both basic and advanced techniques for prostate brachytherapy and is appropriate for the practitioner who is anticipating or currently performing permanent radioactive seed implants. A partial list of topics includes: patient selection, equipment decisions, treatment planning, operative technique, post-implant evaluation, management of acute/long term treatment and follow-up after implant. The accompanying CD-ROM, with video clips, is an invaluable teaching tool. Basic and Advanced Techniques in Prostate Brachytherapy is for practitioners of prostate brachytherapy-urologists, radiation oncologists, medical oncologists and medical physicists.
Author(s): Adam P. Dicker, Gregory Merrick, Leonard Gomella, Richard K. Valicenti, Frank Waterman
Edition: 1
Publisher: Informa Healthcare
Year: 2005
Language: English
Commentary: 62032
Pages: 715
Tags: Медицинские дисциплины;Клинические методы диагностики, лабораторная диагностика;Лучевая диагностика и терапия;
BookCover......Page 1
Title......Page 2
Copyright......Page 3
Contents......Page 4
List of Contributors......Page 9
Acknowledgments......Page 21
Dedication......Page 22
1 Introduction......Page 23
Part I Understanding the problem: fundamentals of pathology and implications for brachytherapy......Page 26
2 Effect of radiotherapy on prostate histopathology and assessment of residual cancer......Page 28
3 What should you ask your pathologist when contemplating minimally invasive therapy?......Page 46
4 Detailed mapping of prostate cancer: implications for brachytherapy......Page 61
5 Defining permanent prostate brachytherapy target volumes from evaluation of whole-mount prostatectomy specimens......Page 71
6 Prostate cancer staging: PSMA-based serum assays and radioscintigraphy......Page 83
Part II Treatment choices: perspectives from the physician and patient......Page 105
7 Treatment decisions: surgery versus brachytherapy. A urologist’s perspective......Page 106
8 Treatment decisions: which therapy? A patient’s perspective......Page 118
Part III Pretreatment and real-time planning for permanent, low dose rate prostate brachytherapy......Page 126
9 Brachytherapy from the urologist’s perspective......Page 127
10 Sonographic anatomy of the prostate......Page 141
11 What to look for when choosing treatmentplanning software for prostate brachytherapy......Page 157
12 Treatment planning for low and high dose rate brachytherapy......Page 164
13 Planning an implant: preoperative versus intraoperative planning......Page 179
14 The Wheeling approach to treatment planning for prostate brachytherapy......Page 186
15 The Seattle Prostate Institute approach to treatment planning for permanent implants......Page 200
16 103Pd brachytherapy: rationale, design, and evaluation......Page 224
17 Ultrasound-guided 103Pd prostate brachytherapy......Page 273
18 Optimizing real-time, interactive, ultrasoundguided prostate brachytherapy......Page 291
19 Real-time prostate brachytherapy: transition from intraoperative nomogram planning to virtual planning......Page 299
20 The ProSeed approach: a multicenter study of the results of brachytherapy training......Page 315
21 Functional image registration in brachytherapy......Page 326
22 A novel prostate brachytherapy technique: use of preloaded needles without spacers. The Frankford Hospital experience......Page 341
23 Radioimmunoguided prostate brachytherapy......Page 351
24 Prostate brachytherapy under local anesthesia......Page 366
25 The impact of hormonal therapy on pubic arch interference......Page 373
26 Using the needle manipulation ruler......Page 385
27 Using the perineal pressure applicator device......Page 391
28 Permanent prostate brachytherapy using sources embedded in absorbable vicryl suture and a preplanned, preloaded needle technique......Page 396
29 The Utrecht technique in RAPIDStrand TM afterloading......Page 405
30 The PIPER prostate brachytherapy planning system......Page 410
31 Robot-aided and 3D TRUS-guided intraoperative prostate brachytherapy......Page 417
32 Initial experience with the FIRST system in Utrecht......Page 439
Part IV Treatment planning and techniques for high dose rate prostate brachytherapy......Page 454
33 High dose rate 192Ir prostate brachytherapy......Page 455
34 High dose rate prostate brachytherapy. Treatment planning and results from Memorial Sloan-Kettering Cancer Center......Page 468
35 High dose rate afterloading 192Ir prostate brachytherapy......Page 478
36 High dose rate brachytherapy in patients with high IPSS, large glands, or with prior TURP......Page 503
Part V Combination of external beam radiotherapy and prostate brachytherapy......Page 524
37 Combining external beam radiotherapy with prostate brachytherapy: issues and rationale......Page 525
38 The role of external beam radiotherapy and permanent prostate brachytherapy in patients with localized prostate cancer......Page 537
39 Simultaneous irradiation for prostate cancer: disease-free survival rates......Page 549
Part VI Permanent radioactive seeds: issues and features......Page 558
40 Radioactive sources for insterstitial brachytherapy......Page 559
41 RADIOCOIL: a coiled wire brachytherapy source......Page 569
42 InterSource® brachytherapy seeds......Page 586
43 The customized monofilament: a new approach to permanent prostate brachytherapy......Page 592
Part VII Postimplant: analysis of postimplant dosimetry......Page 602
44 Salvage of suboptimal prostate seed implantation: re-implantation of an underdosed region of the prostate base......Page 603
45 Can prostate brachytherapy treat potential extraprostatic disease?......Page 612
Part VIII Quality of life and posttreatment sequelae after prostate brachytherapy......Page 621
46 Health-related quality of life following prostate brachytherapy......Page 622
47 Rectal complications following permanent seed implants......Page 629
48 Sexual function following permanent prostate brachytherapy......Page 639
49 Prostate-specific antigen bounce following prostate brachytherapy......Page 653
50 Factors predicting for urinary incontinence following prostate brachytherapy......Page 663
Index......Page 681