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Antitargets: Prediction and Prevention of Drug Side Effects

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This practice-oriented handbook surveys current knowledge on the prediction and prevention of adverse drug reactions related to off-target activity of small molecule drugs. It is unique in collating the current approaches into a single source, and includes several highly instructive case studies that may be used as guidelines on how to improve drug development projects. With its large section on ADME-related effects, this is key knowledge for every drug developer.

Author(s): Roy J. Vaz, Thomas Klabunde, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Series: Methods and Principles in Medicinal Chemistry 38
Edition: 1
Publisher: Wiley-VCH
Year: 2008

Language: English
Pages: 505