Antibody Engineering

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Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity.

Antibody Engineering provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest "hands on" knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.

Author(s): Nina Strebe, Frank Breitling, Dieter Moosmayer, Bodo Brocks, Stefan Dübel (auth.), Roland Kontermann, Stefan Dübel (eds.)
Edition: 2
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2010

Language: English
Pages: 800
Tags: Immunology; Antibodies

Front Matter....Pages i-xiii
Front Matter....Pages 1-1
Front Matter....Pages 3-14
Front Matter....Pages 15-20
Front Matter....Pages 21-44
Front Matter....Pages 43-43
Front Matter....Pages 47-63
Front Matter....Pages 65-84
Back Matter....Pages 85-97
....Pages 99-114