Anatomy & Physiology: The Unity of Form and Function

Anatomy & Physiology: The Unity of Form and Function tells a story comprised of many layers, including core science, clinical applications, the history of medicine, and the evolution of the human body. Saladin combines this humanistic perspective on anatomy and physiology with vibrant photos and art to convey the beauty and excitement of the subject to beginning students. To help students manage the tremendous amount of information in this introductory course, the narrative is broken into short segments, each framed by expected learning outcomes and self-testing review questions. This presentation strategy works as a whole to create a more efficient and effective way for students to learn A&P. Writing Style and Level Saladin’s text is written using plain language for A&P students who may be taking this course early in their curricula. Careful attention has been given to word selection and paragraph structure to maintain the appropriate writing level for all students. CHANGES TO THE NINTH EDITION New Science This edition draws on recent literature and scientific conferences attended by the author to update many topics, including but not limited to molecular, vascular, and brain imaging techniques; peroxisome and mitochondrial behavior; the DNA damage response; gene regulation; epigenetics; the tissue interstitium; regenerative medicine; osteoporosis; prosthetic joints; fibromyalgia; sleep physiology; trigeminal neuralgia; pain physiology; endocrine functions of osseous and adipose tissue; diabetes mellitus; cord blood transplants; thrombopoiesis; AIDS; prostate diseases; breast cancer; aging; life expectancy; and assisted reproductive technology. New Deeper Insight sidebar essays have been added on cardiac tamponade; biopsy; stem-cell therapy; regenerative medicine; osteomalacia and rickets; vertebral disc herniation; rotator cuff injury; carpal tunnel syndrome; shinsplints; calcaneal tendon rupture; plantar fasciitis; brain connectomics and diffusion tensor imaging; lumbar puncture; stroke; blindness; alcoholic ascites; diverticulosis and diverticulitis; colorectal cancer; and cleft lip and palate. While new science has been added, keeping up with such growth also means pruning back topics discredited by newer literature. For this edition, these include adult cerebral neurogenesis; endorphins and runner’s high; human pheromones; pineal tumors and precocial puberty; prophylactic use of low-dose aspirin; myocardial regeneration; female ejaculation; and the free-radical DNA damage theory of senescence. In consideration of user and reviewer suggestions to reduce detail in a few areas, this edition has more concise discussions of some topics: chromatin coiling; apoptosis; skin grafting; the hair cycle; calcium and phosphate homeostasis; and spinal cord tracts. New Art and Photography This edition features new drawings of epidermal histology, flat bone structure, lever mechanics, Parkinson disease, lumbar puncture, hand innervation, Bell palsy, the vagus nerve, olfactory pathways, erythropoiesis, cardiac innervation, regulation of cardiac output, air embolism, colonic histology, lipoprotein structure, cleft lip and palate, and senescent muscle atrophy. New photos in this edition include digital subtraction angiography, molecular-scale cryo-EM imaging, diabetic gangrene, embryonic stem cells, albinism, jaundice, osteocyte SEM, rickets, muscle fiber histochemistry, diffusion tensor imaging of the brain connectome, shingles, cataracts, glaucoma, forelimb veins used for phlebotomy, kidney stones, gallstones, hepatic cirrhosis, MRI of obesity, and intracytoplasmic sperm injection. Organizational Changes For improved readability, narrative descriptions of some systems are moved from tables into chapter text; selected illustrations are moved outside of the tables; and tables are distilled to more concise summaries. These include the skeletal muscles (chapter 10), spinal nerve plexuses (chapter 13), cranial nerves (chapter 14), and blood vessels (chapter 20). A detailed list of changes by chapter follows.