Lyon-RTH Laennec Faculty of Medicine, France. Introduction to key immunotoxicological issues. Considers the health consequences of immunotoxicity and addresses the state-of-the-art methods used to detect and evaluate unexpected immunotoxic effects of xenobiotics, both preclinically and clinically. For undergraduate and graduate students. Hardcover, softcover also available.
Author(s): Jacques Descotes
Edition: 1
Publisher: Taylor & Francis
Year: 1999
Language: English
Commentary: 17248
Pages: 196
City: London; Philadelphia
Tags: Медицинские дисциплины;Иммунология и аллергология;
Book Cover......Page 1
Title......Page 4
Contents......Page 5
Preface page......Page 12
Immunotoxic Effects and their Clinical Consequences......Page 14
Definition and History of Immunotoxicology......Page 16
Overview of the Immune System......Page 24
Immunosuppression and Immunodepression......Page 34
Immunostimulation......Page 44
Hypersensitivity......Page 50
Autoimmunity......Page 64
Major Immunotoxicants......Page 76
Immunotoxicity Evaluation......Page 90
Guidelines......Page 92
Histopathology......Page 102
Assays of Humoral Immunity......Page 110
Assays of Cell-Mediated Immunity......Page 116
Assays of Non-Specific Defences......Page 124
Host Resistance Assays......Page 130
Strategies for the Evaluation of Immunosuppression......Page 138
Identification of Chemical Sensitisers......Page 150
Prediction of Autoimmunity......Page 158
Trends and Perspectives in Immunotoxicology......Page 166
Immunotoxicity Risk Assessment......Page 168
New Methods in Immunotoxicology......Page 172
Human Immunotoxicology......Page 178
Immunotoxicology and Wildlife......Page 188
Index......Page 194
