Enlarged to describe more than a decade of advances in the immunotherapy of allergic diseases and asthma, this Third Edition contains the most recent studies on the mechanisms, manufacture, and standardization of various allergen groups and their utilization in the treatment of allergic diseases—containing 8 new chapters detailing various pharmacoeconomic, regulatory, manufacturing, administration, and safety issues concerning new and emerging immunotherapy techniques.
Author(s): Samuel C. Bukantz, Richard F. Lockey, Jean Bousquet
Series: Clinical allergy and immunology 18
Edition: 3rd ed., rev. and expanded
Publisher: Marcel Dekker
Year: 2004
Language: English
Commentary: 57049
Pages: 831
City: New York
Series Introduction......Page 8
Preface......Page 10
Contents......Page 12
Contributors......Page 16
Allergen Immunotherapy in Historical Perspective......Page 22
Definition of an Allergen (Immunobiology)......Page 58
Allergen Nomenclature......Page 72
Mechanisms of IgE-Mediated Allergic Reactions......Page 86
Immunological Responses to Allergen Immunotherapy......Page 106
Primary and Secondary Prevention of Allergy and Asthma by Allergen Therapeutic Vaccines......Page 126
In Vitro Tests to Monitor Efficacy of Immunotherapy......Page 136
Aerobiology......Page 146
Pharmacoeconomic Considerations for Allergen Immunotherapy......Page 172
Tree Pollen Allergens......Page 186
Grass Pollen Allergens......Page 206
Weed Pollen Allergens......Page 228
Fungal Allergens......Page 244
Mite Allergens......Page 272
Cockroach and Other Inhalant Insect Allergens......Page 292
Mammalian Allergens......Page 318
Food Allergens......Page 340
Hymenoptera Allergens......Page 360
Biting-Insect Allergens......Page 376
Latex Allergens......Page 390
Drug Allergens, Haptens, and Anaphylatoxins......Page 408
Standardized Allergen Extracts in the United States......Page 442
Manufacturing and Standardizing Allergen Extracts in Europe......Page 454
Preparing and Mixing Allergen Vaccines......Page 478
Administration of Allergen Vaccines......Page 502
Immunotherapy for Allergic Rhinoconjunctivitis......Page 516
Allergen Immunotherapy: Therapeutic Vaccines for Asthma......Page 532
Immunotherapy for the Prevention of Allergic Diseases......Page 550
Immunotherapy for Hymenoptera Venom and Biting Insect Hypersensitivity......Page 562
Immunotherapy Combined with Pharmacotherapy......Page 582
Immunotherapy in Young Children......Page 588
Drug Allergy: Desensitization and Treatment of Reactions to Antibiotics and Aspirin......Page 606
Non-Injection Routes for Immunotherapy of Allergic Diseases......Page 628
Anti-IgE Therapy......Page 646
Modifying Allergens and Using Adjuvants for Specific Immunotherapy......Page 662
Novel Approaches to Immunotherapy for Food Allergy......Page 684
Tolerance Induced by Allergen Immunotherapy......Page 702
Unproven and Controversial Forms of lmmunotherapy......Page 724
Adverse Effects and Fatalities Associated with Subcutaneous Allergen Immunotherapy......Page 732
Prevention and Treatment of Anaphylaxis......Page 750
Instructions and Consent Forms for Allergen Immunotherapy......Page 776
Index......Page 806
About the Editors......Page 830
