This volume highlights the latest reviews of mechanisms and actions of the immune system and the host response to infection and inflammation. Key Features * Covers cytokine functioning as influenced by the Janus protein tyrosine kinase family * Explores immunodeficiencies, including: * Immunoglobulin deficiencies and B cells development * Glycosyl Phosphatidylinositol (GPI)-anchor and Paroxysmal Nocturnal Hemoglobinuria (PNH) * Investigates the links molecular pathology established between deficiencies in GPI-anchor synthesis and PNH * Includes the use of Multiple Antigen Peptides (MAPs) to induce protective immune response * Offers a timely update on Eosinophils' role in disease * Covers histology of Germinal center reaction of a spleen twelve days after primary immunization * Includes new research on cytotoxic T-lymphocytes * Presents the multiple roles of Nitric oxide (NO) in the inflammatory response
Author(s): Frank J. Dixon (Ed.)
Edition: 1st
Publisher: Academic Press
Year: 1995
Language: English
Pages: iii-x, 1-388
Tags: Медицинские дисциплины;Иммунология и аллергология;Advances in immunology;
Content:
Edited by
Page iii
Copyright Page
Page iv
Contributors
Pages ix-x
The Janus Protein Tyrosine Kinase Family and Its Role in Cytokine Signaling Original Research Article
Pages 1-35
James N. Ihle
X-Linked Agammaglobulinemia and Immunoglobulin Deficiency with Normal or Elevated IgM: Immunodeficiencies of B Cell Development and Differentiation Original Research Article
Pages 37-56
Ramsay Fuleihan, Narayanaswamy Ramesh, Raif S. Geha
Defective Glycosyl Phosphatidylinositol Anchor Synthesis and Paroxysmal Nocturnal Hemoglobinuria Original Research Article
Pages 57-103
Taroh Kinoshita, Norimitsu Inoue, Junji Takeda
The Use of Multiple Antigen Peptides in the Analysis and Induction of Protective Immune Responses against Infectious Diseases Original Research Article
Pages 105-149
Elizabeth H. Nardin, Giane A. Oliveira, J. Mauricio Calvo-Calle, Ruth S. Nussenzweig
Eosinophils: Biology and Role in Disease Original Research Article
Pages 151-266
Andrew J. Wardlaw, Redwan Moqbel, A. Barry Kay
In Situ Studies of the Germinal Center Reaction Original Research Article
Pages 267-272,272a,272b,273-288
Garnett Kelsoe
Cytotoxic T Lymphocytes: The Newly Identified Fas (CD95)-Mediated Killing Mechanism and a Novel Aspect of Their Biological Functions Original Research Article
Pages 289-321
Hajime Takayama, Hidefumi Kojima, Nobukata Shinohara
The Role of Nitric Oxide in Inflammation Original Research Article
Pages 323-371
C. Rick Lyons
Index
Pages 373-386
Contents of Recent Volumes
Pages 387-388