Adipose tissue represents an abundant and accessible source of adult stem cells with the ability to differentiate along multiple lineage pathways, including cardiac, neural, cartilage, muscle, and bone tissue. The therapeutic potential of the use of adipose stem cells in regenerative medicine has been increasingly recognized, and in recent years concrete clinical benefits have accrued as these cells have been explored for a variety of applications. Without doubt, adipose tissue engineering is now at the inflection point of a sharp upward slope on its developmental curve.
This readable, informative, and well-illustrated textbook tracks the progress that has been made in this fascinating new area of biomedicine. All aspects of the subject are considered, with particular attention to adipose cell biology, adipose tissue engineering strategies, and the diverse clinical applications of adipose stem cells. Funding issues, industrial approaches, and regulatory challenges are also examined, and the book closes by discussing future directions. The two editors have vast experience in the field and have chosen leading experts from different countries to write on each topic. This book will excite the interest of all researchers, clinicians, and students wishing to gain an in-depth understanding of adipose stem cells and their flourishing role in regenerative medicine.
Author(s): Tahsin Murad Aktan, Selcuk Duman (auth.), Yves-Gerard Illouz, Aris Sterodimas (eds.)
Edition: 1
Publisher: Springer-Verlag Berlin Heidelberg
Year: 2011
Language: English
Pages: 278
Tags: Plastic Surgery; Human Genetics; Medical Biochemistry; Laboratory Medicine; Microbiology; Biomaterials
Front Matter....Pages i-xii
Cellular and Molecular Aspects of Adipose Tissue....Pages 1-12
Isolation of Stem Cells from Human Adipose Tissue: Technique, Problems, and Pearls....Pages 13-18
Principles of Liposuction....Pages 19-29
Clinical Applications of Liposuction....Pages 31-44
Principles of Autologous Fat Transplantation....Pages 45-55
Clinical Applications of Autologous Fat Transplantation....Pages 57-65
Adipose Stem Cells: From Liposuction to Adipose Tissue Engineering....Pages 67-81
Storage of Adipose Stem Cells....Pages 83-92
Engineered Scaffolds and Matrices: Tailored Biomaterials for Adipose Stem Cell Engineering....Pages 93-101
Fundamentals and Principles of Biomolecules in Adipose Stem Cell Engineering....Pages 103-109
Gene Therapy Used for Adipose Stem Cell Engineering....Pages 111-119
Stem Cells from Human Adipose Tissue: A New Tool for Pharmacological Studies and for Clinical Applications....Pages 121-132
Role of Adipose Stem Cells Therapy in Obesity....Pages 133-139
Stem Cell Based Cardioregeneration and Adipose Tissue....Pages 141-154
Adipose Stem Cell Engineering: Characterization and Current Application in Neurological Tissue Repair....Pages 155-164
Adipose Stem Cell Engineering: Clinical Applications in Plastic and Reconstructive Surgery....Pages 165-179
Orthopedic Use of Adipose-Derived Stem Cells....Pages 181-191
Adipose-Derived Stem Cells: Characterization and Application in Urology....Pages 193-207
Adipose Stem Cell Engineering: Characterization and Current Application in Otolaryngology....Pages 209-219
Adipose Stem Cell Technologies for Tissue Regeneration in Dentistry....Pages 221-228
Adipose Stem Cells, Tissue Engineering, and Solid Organ Transplantation and Regeneration....Pages 229-243
Industrial Approaches to Adipose Stem Cells Engineering....Pages 245-255
Future Research in Adipose Stem Cell Engineering....Pages 257-272
Conclusions and Future Directions....Pages 273-276
Back Matter....Pages 277-278
