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Advances in Immunology, a long established and highly respected series, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research. * NOW AVAILABLE ONLINE! * Highly respected review series with an impact factor in 2003 of of 7.424 and ranked number 8/114* Contains a 'hot' paper on "New Systems of Variablity and Diversity" by Gary Litman

Author(s): Frederick W. Alt, K. Frank Austen, Tadamitsu Kishimoto, Fritz Melchers, Jonathan W. Uhr, and Emil R. Unanue (Eds.)
Series: Advances in Immunology 87
Edition: 1
Publisher: Elsevier, Academic Press
Year: 2005

Language: English
Pages: 1-343
Tags: Медицинские дисциплины;Иммунология и аллергология;Advances in immunology;

Content:
Role of the LAT Adaptor in T‐Cell Development and Th2 Differentiation Review Article
Pages 1-25
Bernard Malissen, Enrique Aguado, Marie Malissen

The Integration of Conventional and Unconventional T Cells that Characterizes Cell‐Mediated Responses Review Article
Pages 27-59
Daniel J. Pennington, David Vermijlen, Emma L. Wise, Sarah L. Clarke, Robert E. Tigelaar, Adrian C. Hayday

Negative Regulation of Cytokine and TLR Signalings by SOCS and Others Review Article
Pages 61-122
Tetsuji Naka, Minoru Fujimoto, Hiroko Tsutsui, Akihiko Yoshimura

Pathogenic T‐Cell Clones in Autoimmune Diabetes: More Lessons from the NOD Mouse Review Article
Pages 123-162
Kathryn Haskins

The Biology of Human Lymphoid Malignancies Revealed by Gene Expression Profiling Review Article
Pages 163-208
Louis M. Staudt, Sandeep Dave

New Insights into Alternative Mechanisms of Immune Receptor Diversification Review Article
Pages 209-236
Gary W. Litman, John P. Cannon, Jonathan P. Rast

The Repair of DNA Damages/Modifications During the Maturation of the Immune System: Lessons from Human Primary Immunodeficiency Disorders and Animal Models Review Article
Pages 237-295
Patrick Revy, Dietke Buck, Françoise le Deist, Jean‐Pierre de Villartay

Antibody Class Switch Recombination: Roles for Switch Sequences and Mismatch Repair Proteins Review Article
Pages 297-328
Irene M. Min, Erik Selsing

Contributors
Pages ix-x

Index
Pages 329-338

Contents of Recent Volumes
Pages 339-343

Contents
Pages v-viii