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Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions are now augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change meets the needs of the pharmaceutical community and allows the development of a timely vehicle for publishing review materials on this topic. While offering comprehensive and specialised chapters, Profiles of Drug Substances, Excipients and Related Methodology, Volume 32 also presents a methodology review article on the validation of chromatographic methods of analysis, as well as a summary of the publications in 2004 that dealt with polymorphism and solvatomorphism. Read more... Abstract: Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions are now augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change meets the needs of the pharmaceutical community and allows the development of a timely vehicle for publishing review materials on this topic. While offering comprehensive and specialised chapters, Profiles of Drug Substances, Excipients and Related Methodology, Volume 32 also presents a methodology review article on the validation of chromatographic methods of analysis, as well as a summary of the publications in 2004 that dealt with polymorphism and solvatomorphism

Author(s): Harry G. Brittain (Eds.)
Series: Profiles of Drug Substances, Excipients and Related Methodology 32
Publisher: Academic Press
Year: 2005

Language: English
Pages: 1-289
City: [S.l.]

Content:
Series Editors
Page ii

Contents
Pages v-vii

Contributors
Page ix

Preface
Page xi

Miconazole Nitrate: Comprehensive Profile Review Article
Pages 3-65
Abdullah A. Al‐Badr

Niclosamide: Comprehensive Profile Review Article
Pages 67-96
Badraddin M.H. Al‐Hadiya

Oxytetracycline: Analytical Profile Review Article
Pages 97-117
Mochammad Yuwono, Gunawan Indrayanto

Penicillamine: Physical Profile Review Article
Pages 119-130
Abdulrahman Al‐Majed, Fathallah Belal, Saeed Julkhuf, Hussein El‐Subbagh

Penicillamine: Analytical Profile Review Article
Pages 131-148
Abdulrahman Al‐Majed, Fathallah Belal, Saeed Julkhuf

Penicillamine: Adsorption, Distribution, Metabolism, and Elimination Profile Review Article
Pages 149-152
Abdulrahman Al‐Majed, Fathallah Belal, Saeed Julkhuf

Primaquine Diphosphate: Comprehensive Profile Review Article
Pages 153-208
Abdullah A. Al‐Badr

Valproic Acid and Sodium Valproate: Comprehensive Profile Review Article
Pages 209-240
Ibrahim A. Alsarra, M. Al‐Omar, F. Belal

Validation of Chromatographic Methods of Analysis Review Article
Pages 243-259
Mochammad Yuwono, Gunawan Indrayanto

Polymorphism and Solvatomorphism 2004 Review Article
Pages 263-283
Harry G. Brittain

Cumulative Index
Pages 285-289