Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients. * Presents comprehensive reviews covering all aspects of drug development and formulation of drugs * Profiles creatine monohydrate and fexofenadine hydrochloride, as well as five others * Meets the information needs of the drug development community. Read more... Content: Aripiprazole: Polymorphs and Solvatomorphs Harry G. Brittain Amlodipine Besylate Gennady Ananchenko, Jasmina Novakovic and Johnathan Lewis Candesartan cilexetil Febry Ardiana, Maria L. A. D. Lestari and Gunawan Indrayanto Flurbiprofen Alaa A.-M. Abdel-Aziz, Abdullah A. Al-Badr and Gamal Abdel Hafez Gatifloxacin Ebtehal S. Al-Abdullah Lamotrigine Kevin Beattie, Geeta Phadke and Jasmina Novakovic Pimozide Robert Smyj, Xiao-Ping Wang and Feixue Han Risperidone David Germann, Natalie Kurylo and Feixue Han Sunitinib Malate Mohammed Gabr Kassem, A.F.M. Motiur Rahman , Hesham M. Korashy Varenicline Mohammed Gabr Kassem, Abdullah M. Al Hossaini Zolpidem Tartrate Nagwa H. Foda, Shaimaa M. Badr-Eldin Validation of Analytical Methods -- Update 2011 Gunawan Indrayanto. Chapter 1: Buclizine -- Chapter 2: Chitin -- Chapter 3: Ezetimibe -- Chapter 4: Gemifloxacin -- Chapter 5: Glimepiride -- Chapter 6: Lornoxicam -- Chapter 7: Magnesium Silicate -- Chapter 8: Tadalafil -- Chapter 9: Direct Crystallization of Enantiomers and Dissociable Diastereomers -- Chapter 10: Cocrystal Systems of Pharmaceutical Interest: 2009. Abstract: Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients. * Presents comprehensive reviews covering all aspects of drug development and formulation of drugs * Profiles creatine monohydrate and fexofenadine hydrochloride, as well as five others * Meets the information needs of the drug development community