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Hydrotropic solubilization of poorly watersoluble drugs

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Hydrotropic solubilization of poorly watersoluble drugs

... solubility and solubilization (see text). JOURNAL OF PHARMACEUTICAL SCIENCES, VOL. 99, NO. 9, SEPTEMBER 2010 DOI 10 ... 30. Valvani SC, Yalkowsky SH, Amidon GL. 1976. Solubility of nonelectrolytes in polar solvents. VI. Refinements in molecular surface area computations. J Phys Chem 80:829 ...

http://www.kinam.com/Articles/PMicelles%20Papers/Kim,%20J.%2010%20J%20Pharm%20Sci.pdf

Date added: April 25, 2012 - Views: 30

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Solubility of gases in liquids: a critical review

Solubility of gases in liquids: a critical review ... relatively simple aqueous solutions of nonelectrolytes, which may ... (solubilization) (47). Given this wide scope it is not surprising that the subject of gas solubility in liquids has 303.

http://pac.iupac.org/publications/pac/pdf/1985/pdf/5702x0303.pdf

Date added: December 14, 2012 - Views: 11

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Experimental and Computational Methods Pertaining to Drug ...

I is predominant whereas for nonelectrolytes S M is the Solvent molecules Solute molecules Solution www.intechopen.com. ... solubility of drug, is the solubilization power of the cosolvent and theoretically is equal to (log(/ )) ...

http://cdn.intechopen.com/pdfs/28120/InTech-Experimental_and_computational_methods_pertaining_to_drug_solubility.pdf

Date added: October 1, 2012 - Views: 3

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CHAPTER -I INTRODUCTION - INFLIBNET

nonelectrolytes have been studied by Yalkowsky and Valvani(4) ... In order to gain as insight into the probable mechanism of solubilization; solubility, spectral, solution properties, gel formation, paste formation, TLC and IR

http://shodhganga.inflibnet.ac.in/bitstream/10603/6439/7/07_chapter%201.pdf

Date added: July 27, 2013 - Views: 7

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ASSOCIATE EDITOR: ARTHUR CHRISTOPOULOS Strategies to Address ...

For nonelectrolytes, solubility behavior is not complicated by the effects of ... enhance drug solubility via micellar solubilization. Surfactants are generally limited to those that are nonionic because of their more favorable safety profile

http://pharmrev.aspetjournals.org/content/65/1/315.full.pdf

Date added: February 14, 2014 - Views: 2

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SOLUTIONS - Pennsylvania State University

Nonelectrolytes not ionized in solution non-conductors. ... determine its solubility Simplified Rules: (1) Almost all ammonium and alkali metal salts are soluble (2) Most nitrates, acetates, chlorides, ... equals rate of solubilization ...

http://courses.chem.psu.edu/chem110/faculty/asbury/Lec28-30_web.pdf

Date added: February 5, 2012 - Views: 5

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Experimental and Computational Methods Pertaining to Drug ...

solution. For strong electrolytes, SI is predominant whereas for nonelectrolytes S M is the Solvent molecules Solute molecules ... complexation, solubilization) increases the solubility and the common ion effect decreases the solubility and no change in the solubility might mean that drug is ...

http://cdn.intechopen.com/pdfs-wm/28120.pdf

Date added: June 6, 2014 - Views: 1

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ESTIMATION OF ETHANOL /WATER SOLUBILITY PROFILES by Stephen ...

SOLUBILITY STUDY SOLUBILIZATION AND PREFORMULATION STUDY OF ANTALARMIN: A NOVEL STRESS INHIBITOR 6.1. Introduction ... liquid nonelectrolytes,” J. Pharm. Sci., 70, 502-507. Title: Microsoft Word - Dissertation.doc Author: machatha Created Date:

http://arizona.openrepository.com/arizona/bitstream/10150/193915/1/azu_etd_1659_sip1_m.pdf

Date added: May 20, 2013 - Views: 1

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Dear Patrons & Well Wishers Contents - BS Publication- S

Solubility and Solubilization of Nonelectrolytes 2. Drug Solubilization in Surfactant Systems 3. Solubilization of Drugs by cosolvents 4. Alteration of Apparent Solubility through Complexation 5. Solubilization by Solid-State Manipulation 6.

http://www.bspublications.net/downloads/04ee5d014c46f5_PMP%20catalogue-Jan-2012.pdf

Date added: September 19, 2012 - Views: 13

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HANDBOOK OF Aqueous Solubility Data

Handbook of aqueous solubility data : ... and four books. His most recent book Solubility and Solubilization in Aqueous Media, ACS-Oxford, was published in 1999. Dr. Yalkowsky co-authored ... solubility of a wide variety of organic nonelectrolytes and unionized weak electrolytes in water.

http://f3.tiera.ru/3/Chemistry/References/Yalkowsky%20S..,%20He%20Y.%20Handbook%20of%20Aqueous%20Solubility%20Data%20(CRC,%202003)(ISBN%200849315328)(1513s).pdf

Date added: March 16, 2014 - Views: 1

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FACULTY OF PHARMACY ϵϥناعنا Ϧادϯسنا عماج

solubility – factores affecting solubility –classification of solvents ... osmotic pressure of nonelectrolytes –van’t Hoff and morse equations for osmotic pressure ... (micelle formation and solubilization ,antibacterial activity , ...

http://www.siu-sd.com/library/curriculum/ph/PHARMA_Semester%203.pdf

Date added: August 3, 2013 - Views: 1

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A Method for Determining the 1-Octanol/Water Partition ...

Stable and hydrophobic nonelectrolytes are generally more or less volatile. The new ... solubilization effect on a volatile solute, ... 1. S. H. Yalkowsky and S. Banerjee, "Aqueous Solubility, Methods of Estimation for Organic Compounds", Marcel Dekker, New York, 1992. 2. A ...

http://pdf.lookchem.com/pdf/22/afbad729-f297-4977-b9e4-1cb291fe4c5e.pdf

Date added: May 26, 2013 - Views: 2

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CV updated 05 30 031-1 - University of Wisconsin–Madison

Solubilization of Water by Dialkyl Sodium Sulfosuccinates in Hydrocarbon Solution” (with S.G. Frank), J. Colloid and Interface Sci., 29, ... “Solubility of Nonelectrolytes in Polar Solvents, III” (with S.H. Yalkowsky, G.L. Amidon,

http://apps.pharmacy.wisc.edu/facstaff/sciences/Zografi.pdf

Date added: January 11, 2013 - Views: 4

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Study of Charged Particles Transport across Model and Real ...

rate of diffusion of organic molecules – nonelectrolytes ... The higher is the molecular solubility in fats, the faster is the diffusion rate across the membrane. ... with solubilization of heavy metals using low molecular

http://www.wseas.us/e-library/transactions/environment/2010/89-307.pdf

Date added: January 26, 2013 - Views: 2

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Study of Charged Particles Transport across Model and Real ...

rate of diffusion of organic molecules – nonelectrolytes ... The higher is the molecular solubility in fats, the faster is the diffusion rate across the membrane. ... for their solubilization). Those thoroughly studied [3]

http://www.wseas.us/e-library/conferences/2009/tenerife/EED/EED-36.pdf

Date added: May 26, 2013 - Views: 2

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Parámetro de Solubilidad Requerimiento Dieléctrico Nipasol ...

"Dielectric requireinent and solubility parameter of nipagyn and ... ques of solubilization of Drugs". Marcel Dek- ker ... A.N. Paruta (1964) College of Pharmacy 53: 463-4 5. Hildebrand, J.H. & R.L. Scott (1949) "7be Solu- bility of Nonelectrolytes" 3rd Ed., Reinhold Pu ...

http://www.latamjpharm.org/trabajos/19/1/LAJOP_19_1_1_9_H531T5ZG1Y.pdf

Date added: March 20, 2013 - Views: 2