A full-color clinical reference covering both common and uncommon blood disorders—distilled from the world’s leading hematology text
Williams Manual of Hematology, Tenth Edition provides a concise, easy-to-navigate compilation of the pathogenic, diagnostic, and therapeutic essentials of blood cell and coagulation protein disorders. Referenced to the classic Williams Hematology, this portable guide has been carefully edited to deliver only the most clinical point-of-care facts, making differential diagnosis faster, easier, and more efficient. This updated edition reflects the latest research and includes more than 100 full-color clinical photographs.
Concise but comprehensive, this complete guide includes sections on:
Initial Clinical Evaluation
Disorders of Red Cells
Disorders of Granulocytes
Disorders of Monocytes and Macrophages
Principles of Therapy for Neoplastic Hematological Disorders
The Clonal Myeloid Disorders
The Polyclonal Lymphoid Diseases
The Clonal Lymphoid and Plasma Cell Diseases
Disorders of Platelet and Hemostasis
Disorders of Coagulation Proteins
Thrombosis and Antithrombotic Therapy
Transfusion and Hemapheresis
Author(s): Marshall A. Lichtman, Kenneth Kaushansky, Josef T. Prchal, Marcel M. Levi, Linda J. Burns, David C. Linch
Edition: 10
Publisher: McGraw Hill
Year: 2022
Language: English
Commentary: TRUE PDF
Tags: Hematology; Blood Diseases
Cover
Williams Manual of Hematology
Title
Copyright
Preface
PART I INITIAL CLINICAL EVALUATION
Approach to the Patient
PART II DISORDERS OF RED CELLS
Classification of Anemias and Erythrocytoses
Aplastic Anemia: Acquired and Inherited
Pure Red Cell Aplasia
Anemia of Chronic (Inflammatory, Neoplastic, and Renal) Disease
Erythropoietic Effects of Endocrine Disorders
Congenital Dyserythropoietic Anemias
Folate, Cobalamin, and Megaloblastic Anemias
Iron Deficiency and Iron Overload
Anemia Resulting from Other Nutritional Deficiencies
Hereditary and Acquired Sideroblastic Anemias
Anemia Resulting from Marrow Infiltration
Erythrocyte Membrane Disorders
Hemolytic Anemia Related to Red Cell Enzyme Defects
The Thalassemias
The Sickle Cell Diseases and Other Hemoglobinopathies
Unstable Hemoglobins and Hemoglobins with Altered Oxygen Affinity
Methemoglobinemia and Other Dyshemoglobinemias
Fragmentation Hemolytic Anemia
Hemolytic Anemia Resulting from a Chemical or Physical Agent
Hemolytic Anemia Resulting from Infectious Agents
Hemolytic Anemia Resulting from Warm-Reacting Antibodies
Cryopathic Hemolytic Anemia
Drug-Induced Hemolytic Anemia
Alloimmune Hemolytic Disease of the Newborn
Hypersplenism and Hyposplenism
Polyclonal Erythrocytoses (Primary and Secondary)
The Porphyrias
PART III DISORDERS OF GRANULOCYTES
Classification and Clinical Manifestations of Neutrophil Disorders
Neutropenia and Neutrophilia
Disorders of Neutrophil Function
Eosinophils and Their Disorders
Basophils, Mast Cells and Their Disorders
PART IV DISORDERS OF MONOCYTES AND MACROPHAGES
Classification and Clinical Manifestations of Monocyte and Macrophage Disorders
Monocytosis and Monocytopenia
Inflammatory and Malignant Histiocytosis
Gaucher Disease and Related Lysosomal Storage Diseases
PART V PRINCIPLES OF THERAPY FOR NEOPLASTIC HEMATOLOGIC DISORDERS
Pharmacology and Toxicity of Antineoplastic Drugs
Principles of Hematopoietic Cell Transplantation
Immune Cell Therapy: Genetically Engineered T Cells
PART VI THE CLONAL MYELOID DISORDERS
Classification and Clinical Manifestations of the Clonal Myeloid Disorders
Polycythemia Vera
Essential Thrombocythemia
Paroxysmal Nocturnal Hemoglobinuria
Myelodysplastic Syndromes
The Acute Myelogenous Leukemias
The Chronic Myelogenous Leukemias
Primary Myelofibrosis
PART VII THE POLYCLONAL LYMPHOID DISEASES
Classification and Clinical Manifestations of Polyclonal Lymphocyte and Plasma Cell Disorders
Lymphocytosis and Lymphocytopenia
Primary Immunodeficiency Syndrome
Hematologic Manifestations of the Acquired Immunodeficiency Syndrome
The Mononucleosis Syndromes
PART VIII THE CLONAL LYMPHOID ANDPLASMA CELL DISEASES
Classification and Clinical Manifestations of the Neoplastic Lymphocytic Disorders
The Acute Lymphoblastic Leukemias
The Chronic Lymphocytic Leukemias
Hairy Cell Leukemia
Large Granular Lymphocytic Leukemia
General Considerations of Lymphoma: Epidemiology, Etiology, Heterogeneity, and Primary Extranodal Disease
Hodgkin Lymphoma
Diffuse Large B-Cell Lymphoma and Related Diseases
Follicular Lymphoma
Mantle Cell Lymphoma
Marginal Zone B-Cell Lymphoma
Burkitt Lymphoma
Cutaneous T-Cell Lymphoma
Mature T-Cell and Natural Killer Cell Lymphomas
Essential Monoclonal Gammopathy
Myeloma
Macroglobulinemia
Heavy-Chain Diseases
Amyloidosis
PART IX DISORDERS OF PLATELETS AND HEMOSTASIS
Clinical Manifestations, Evaluation and Classification of Disorders of Hemostasis
Thrombocytopenia
Hereditary and Reactive (Secondary) Thrombocytosis
Hereditary Platelet Disorders
Acquired Platelet Disorders
The Vascular Purpuras
PART X DISORDERS OF COAGULATION PROTEINS
Hemophilia A and B
von Willebrand Disease
Hereditary Disorders of Fibrinogen
Inherited Deficiencies of Coagulation Factors II, V, VII, X, XI, and XIII and Combined Deficiencies of Factor V and VIII and of
Antibody-Mediated Coagulation Factor Deficiencies
Hemostatic Dysfunction Related to Liver Diseases
The Antiphospholipid Syndrome
Disseminated Intravascular Coagulation
Fibrinolysis and Thrombolysis
PART XI THROMBOSIS AND ANTITHROMBOTIC THERAPY
Principles of Antithrombotic and Antifibrinolytic Therapy
Hereditary Thrombophilia
Venous Thromboembolism
Antibody-Mediated Thrombotic Disorders: Thrombotic Thrombocytopenic Purpura and Heparin-Induced Thrombocytopenia
PART XII TRANSFUSION AND HEMAPHERESIS
Red Cell Transfusion
Transfusion of Platelets
Plasma and Plasma Component Therapy
Therapeutic Hemapheresis
Table of Normal Values
