Raney Nickel-Assisted Synthesis of Heterocycles covers the synthesis of heterocycles using Raney nickel. The book focuses on the use of Raney-Ni, a common catalyst in hydrogenation reaction and its uses in the synthesis and preparation of heterocycles. Furthermore, it explains how the development of new approaches and strategic deployments in known approaches for the formation of complex heterocyclic compounds continue to drive the field of synthetic organic chemistry, along with updates on efforts to prepare heterocycles through the development of new and efficient synthetic transformations.
Heterocyclic chemistry is an inexhaustible source of novel compounds, providing the most diverse chemical, physical and biological properties through the design of a wide range of combinations of carbon, hydrogen and heteroatoms. Significant focus has been paid to novel approaches to the formation of heterocyclic compounds, which are of practical use acting as modifiers and additives in a wide range of industries such as reprography, plastics, cosmetics, vulcanization accelerators, solvents, antioxidants and information storage.
Author(s): Navjeet Kaur
Publisher: Elsevier
Year: 2022
Language: English
Pages: 230
City: Amsterdam
Front cover
Half title
Title
Copyright
Contents
Preface
About the author
Abbreviations
Chapter 1 Raney nickel-assisted nitro group reduction for the synthesis of five-membered N-heterocycles
1.1 Introduction
1.2 Nitro group reduction involved in the synthesis of pyrroles
1.3 Nitro group reduction involved in the synthesis of fused pyrroles
1.4 Nitro group reduction involved in the synthesis of indoles
1.5 Nitro group reduction involved in the synthesis of fused indoles
1.6 Nitro group reduction involved in the synthesis of pyrazoles
1.7 Nitro group reduction involved in the synthesis of imidazoles and benzimidazoles
1.8 Nitro group reduction involved in the synthesis of triazoles
References
Chapter 2 Raney nickel-assisted nitro group reduction for the synthesis of N-, O-, and S-heterocycles
2.1 Introduction
2.2 Reduction of NO2 group for the synthesis of five-membered O- and S-heterocycles
2.3 Reduction of NO2 group for the synthesis of six-membered N-heterocycles
2.4 Reduction of NO2 group for the synthesis of six-membered N,N-heterocycles
2.5 Reduction of NO2 group for the synthesis of six-membered N,N,N-heterocycles
2.6 Reduction of NO2 group for the synthesis of six-membered O-heterocycles
2.7 Reduction of NO2 group for the synthesis of seven-membered heterocycles
References
Chapter 3 Synthesis of heterocycles from cyanide, oxime, and azo compounds using Raney nickel
3.1 Introduction
3.2 Synthesis of heterocycles from cyanide compounds
3.2.1 Synthesis of five-membered heterocycles from cyanide compounds
3.2.2 Synthesis of six-membered heterocycles from cyanide compounds
3.2.3 Synthesis of seven-membered heterocycles from cyanide compounds
3.3 Synthesis of heterocycles from oxime compounds
3.3.1 Synthesis of five-membered heterocycles from oxime compounds
3.3.2 Synthesis of six-membered heterocycles from oxime compounds
3.4 Synthesis of heterocycles from azo compounds
References
Chapter 4 Synthesis of heterocycles from oxazoles and oxazines using Raney nickel
4.1 Introduction
4.2 Synthesis of five-membered N-heterocycles from oxazoles
4.3 Synthesis of five-membered N-heterocycles from oxazines
4.4 Synthesis of five-membered fused N-heterocycles from oxazoles and oxazines
4.5 Synthesis of five-membered O-heterocycles from oxazoles and oxazines
4.6 Synthesis of six-membered heterocycles from oxazoles and oxazines
4.7 Synthesis of higher-membered heterocycles from oxazoles and oxazines
References
Chapter 5 Miscellaneous use of Raney nickel for the synthesis of heterocycles
5.1 Introduction
5.2 Synthesis of five-membered N-heterocycles
5.3 Synthesis of five-membered N-polyheterocycles
5.4 Synthesis of five-membered fused N-heterocycles
5.5 Synthesis of five-membered N,N-heterocycles
5.6 Synthesis of five-membered N,N,N-heterocycles
5.7 Synthesis of five-membered O-heterocycles
5.8 Synthesis of five-membered O,N- and S-heterocycles
5.9 Synthesis of six-membered N-heterocycles
5.10 Synthesis of six-membered N,N-heterocycles
5.11 Synthesis of six-membered O-heterocycles
5.12 Synthesis of seven-membered heterocycles
References
Conclusion
Index
Back cover
