Humana Press, 2012. - 329 p. - Super secondary structure(SSS) helps to understand the relationship between primary and tertiary structure of proteins. In Protein Supersecondary Structure: Methods and Protocols expert researchers in the field detail the usefulness of the study of super secondary structure in different areas of protein research. This is done through four main studies SSS representation, SSS prediction, SSS and protein folding, and other application of SSS concept to protein biology. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Protein Supersecondary Structure: Methods and Protocols highlight some of the major advances in the many fast-growing areas of supersecondary structure research.Contents
Super-secondary Structure: A Historical Perspective
Representation of Supersecondary Structure
Hierarchical Representation of Super-secondary Structures Using a Graph-theoretical Approach
Up, Down and Around: Identifying Recurrent Interactions Within and Between Super Secondary Structures in b-Propellers
Structure Description and Identification using the Tableau Representation of Protein Folding Patterns
Super-secondary Structure Prediction
Computational Prediction of Secondary and Supersecondary Structures
A Survey of Machine Learning Methods for Secondary and Supersecondary Protein Structure Prediction
Beyond Supersecondary Structure: The Global Properties of Protein Sequences
Creating Supersecondary Structures with BuildBeta
A Modular Perspective of Protein Structures; Application to Fragment Based Loop Modeling
Residue-residue Contacts: Application to Analysis of Secondary Structure Interactions
Supersecondary Structure and Protein Folding
Super-secondary Structures and Modeling of Protein Folds
Computational Simulations of Protein Folding to Engineer Amino Acid Sequences to Encourage Desired Supersecondary Structure Formation
Protein Folding at Atomic Resolution: Analysis of Autonomously Folding Supersecondary Structure Motifs by Nuclear Magnetic Resonance
Artificial Supersecondary Structures Based on Aromatic Oligoamides
Other Applications of Supersecondary Structure to Protein Biology
Cross-b-sheet Super-secondary Structure in Amyloid Folds: Techniques for Detection and Characterization
Analyzing Oligomerization of Individual Transmembrane Helices and of Entire Membrane Proteins in E. coli: A Hitchhiker´s Guide to GALLEX
Super-secondary Structure Prediction of Transmembrane Beta-Barrel Proteins
Functional Structural Motifs for Protein-ligand, Protein-protein and Protein-nucleic Acid Interactions and their Connection to Supersecondary Structures
