This new edition is a comprehensive yet concise text that combines current treatment protocols and practical pharmacological information for GI Disease. Each chapter addresses a specific GI disease or condition and lists all agents available for that condition, including all brand and generic names, indications, contraindications, lactation and pregnancy information, doses, routes of administration, duration, and relative cost. Special features include tables, algorithms, and key references. The book also has chapter tabs for easy access, a durable cover to withstand frequent use, and fits in a white coat pocket. The third edition has been updated with information on new medications for the treatment of GI diseases including esophageal motility, peptic diseases, bacterial and fungal infections, parasitic, malabsorptive, inflammatory bowel and viral hepatitis, as well as genetic diseases. Written by experts in the field, Pocket Handbook of GI Pharmacotherapeutics, Third Edition is a valuable and portable resource of use to anyone involved in the treatment of patients with GI disease.
Author(s): Marianna G. Mavilia; George Y. Wu
Series: Clinical Gastroenterology
Edition: 3
Publisher: Humana
Year: 2021
Language: English
Pages: 276
City: New York
Preface
Relative Cost
Contents
Contributors
1: Gastroesophageal Disorders
Meclizine
Dimenhydrinate
Ondansetron
Scopolamine Patch
Gastroesophageal Reflux Disorder (GERD) and Peptic Ulcer Disease (PUD)
Proton Pump Inhibitors (PPI)
Omeprazole
Esomeprazole Magnesium (Oral)
Esomeprazole Sodium (IV)
Lansoprazole
Pantoprazole Sodium Oral and IV
Rabeprazole Sodium
Dexlansoprazole
Histamine H2 Antagonists
Famotidine
Other Agents
Sucralfate
Suggested Reading
2: Gastrointestinal Bleeding
Pantoprazole
Esomeprazole
Octreotide Acetate
Vasopressin
Metoclopramide
Erythromycin
Epinephrine
Hemostatic Nanopowder
Suggested Reading
3: Specific Gastrointestinal Motility Disorders
Nifedipine
Botulinum Toxin (Onabotulinum Toxin A)
Isosorbide Dinitrate
Gastroparesis
Erythromycin
Metoclopramide
Azithromycin
Prucalopride
Domperidone
Dumping Syndrome and Accelerated Gastric Emptying
Octreotide
Dexlansoprazole
Rapid Transit Dysmotility of the Small Bowel
Loperamide
Suggested Reading
4: General Gastrointestinal Motility Disorders
Diarrhea
Dicyclomine Hydrochloride
Hyoscyamine Sulfate
Diphenoxylate Hydrochloride/Atropine Sulfate
Loperamide
Cholestyramine
Imipramine
Amitriptyline
Constipation
Psyllium
Methylcellulose
Docusate
Magnesium Citrate
Mineral Oil
Polyethylene Glycol
Lactulose
Senna
Bisacodyl
Castor Oil
Lubiprostone
Linaclotide
Plecanatide
Prucalopride
Irritable Bowel Syndrome-Diarrhea Predominant (IBS-D)
Rifaximin
Alosetron
Eluxadoline
Irritable Bowel Syndrome-Constipation Predominant (IBS-C)
Tegaserod
Tenapanor
Suggested Reading
5: Inflammatory Bowel Disease
Sulfasalazine
Mesalamine
Olsalazine
Balsalazide
Glucocorticoids: Prednisone, Methylprednisolone and Hydrocortisone
Budesonide
Hydrocortisone Retention Enema
6-Mercaptopurine (6-MP)
Azathioprine
Methotrexate (MTX)
Cyclosporine
Infliximab
Adalimumab
Certolizumab Pegol
Golimumab
Natalizumab
Vedolizumab
Ustekinumab
Tofacitinib
Suggested Monitoring for IBD Drugs
Suggested Reading
6: General Gastrointestinal Infections
Treatment of Acute Diverticulitis
Cefotaxime
Ceftriaxone
Cefepime
Metronidazole
Levofloxacin
Ciprofloxacin
Sulfamethoxazole and Trimethoprim
Piperacillin-Tazobactam
Ertapenem
Infective Endocarditis Prophylaxis for GI Procedures
Suggested Reading
7: Specific Gastrointestinal Microbial Infections
Clostridioides (formerly Clostridium) difficile Pseudomembranous Colitis
Vancomycin
Fidaxomicin
Metronidazole
Helicobacter pylori
Amoxicillin
Bismuth Subsalicylate
Clarithromycin
Levofloxacin
Tinidazole
E. coli (EP and EI) Gastroenteritis
Shigella Colitis
Salmonella Gastroenteritis
Campylobacter Gastroenteritis
Vibrio cholerae
Yersinia Gastroenteritis
Listeria monocytogenes
Trimethoprim-Sulfamethoxazole
Ciprofloxacin
Whipple Disease
Azithromycin
Erythromycin
Doxycycline
Tetracycline
Fungal Infections
Fluconazole
Voriconazole
Caspofungin
Clotrimazole
Cryptosporidium hominis
Cyclospora cayetanensis
Nitazoxanide
Viral Infections
Ganciclovir
Valganciclovir
Foscarnet
Protozoan Infections
Amebiasis
Giardiasis
Parasitic Infestations
Ascariasis (A. lumbricoides)
Cutaneous Larva Migrans
Cysticercosis (Taenia solium)
Dracunculiasis (Guinea Worm Disease)
Echinococcosis (Hydatid Cyst)
Enterobiasis (Pinworm)
Hook Worm (Ancylostomiasis)
Lymphatic Filariasis (W. bancrofti, B. malayi, B. timori)
Loaisis (M. streptocerca, O. volvulus, D. medinensis)
Tropical Pulmonary Eosinophilia
Trypanosoma cruzi (Chagas Disease)
Onchocerciasis (River Blindness)
Fluke Infections
Schistosomiasis
Strongyloidiasis
Tapeworm Intestinal Infections (Taenia saginata)
Trichinellosis (Roundworm)
Trichuriasis (Whipworm)
Albendazole
Mebendazole
Ivermectin
Praziquantel
Thiabendazole: No Longer Available in the USA
Pyrantel Pamoate
Tinidazole
Paromomycin
Iodoquinol
Diethylcarbamazine
Benznidazole
Triclabendazole
Suggested Reading
8: Hepatitis
Chronic Hepatitis B
Entecavir
Tenofovir Dipovoxil Fumarate (TDF)
Tenofovir Alafenamide (TAF)
Pegylated Interferon α-2a
Dosage Adjustments for PEG-Interferon α-2a (Pegasys)
Pegylated Interferon α-2b
Dosage adjustments for PEG-interferon α-2b:
Lamivudine
Adefovir Dipivoxil
Chronic Hepatitis C
Sofosbuvir
Ledipasvir/Sofosbuvir
Glecaprevir/Pibrentasvir
Elbasvir/Grazoprevir
Sofosbuvir/Velpatasvir/Voxilaprevir
Daclatasvir
Ribavirin
Ribavirin Dosage Adjustments
Pegylated Interferon α-2a
Autoimmune Hepatitis
Azathioprine
Prednisone
Budesonide
Mycophenylate Mofetil (MMF)
Alcoholic Hepatitis
Prednisolone
Suggested Reading
9: Portal Hypertension
Nadolol
Propranolol
Carvedilol
Suggested Reading
10: Cholestasis
Primary Biliary Cholangitis (PBC)
Ursodiol, Ursodeoxycholic Acid (UDCA)
Obeticholic Acid (OCA)
Primary Sclerosing Cholangitis (PSC)
UDCA
Suggested Reading
11: Hepatic Encephalopathy
Lactulose
Neomycin
Rifaximin
Suggested Reading
12: Ascites
Ascites Management
Furosemide
Spironolactone
Spontaneous Bacterial Peritonitis (SBP)
Cefotaxime
Ofloxacin
Ceftriaxone
Norfloxacin
Trimethoprim-Sulfamethoxazole
Albumin
Suggested Reading
13: Overload Disorders
Hereditary Hemochromatosis
Deferoxamine
Deferasirox
Wilson’s Disease
Penicillamine
Trientine
Tetrathiomolybdate
Zinc Sulfate
Gaucher’s Disease
Imiglucerase (Glucocerebrosidase)
Velaglucerase Alfa (Glucocerebrosidase)
Taliglucerase Alfa
Miglustat
Eliglustat
Suggested Reading
14: Pruritus
Diphenhydramine
Hydroxyzine
Cholestyramine
Rifampin
Ursodeoxycholic Acid
Naltrexone
Sertraline
Suggested Reading
15: Post-Liver Transplant
Immunosuppressant Drugs
Glucocorticoids
Tacrolimus
Cyclosporine
Azathioprine
Mycophenolate Mofetil
Sirolimus
Everolimus
Infection Prophylaxis Agents
Antifungal Prophylaxis
PCP Prophylaxis
Antiviral Prophylaxis
Suggested Reading
16: Acute and Chronic Pancreatitis Pain Syndromes
Tramadol
Renal Insufficiency
Hepatic Impairment
Hydromorphone
Gabapentin
Amitriptyline
Duloxetine
Octreotide
Celiac/Splanchnic Nerve Block
Suggested Reading
17: Pancreatic Insufficiency
Pancrelipase
Suggested Reading
18: Gut Malabsorption and Enzyme Deficiencies
Lactase Deficiency
Lactase
Vitamin B12 Deficiency/Pernicious Anemia
Vitamin B12 (Cyanocobalamin)
Vitamin B12 Deficiency
Pernicious Anemia
Small Intestinal Bacterial Overgrowth (SIBO)
Non-absorbable Antibiotics
Systemic Antibiotics
Neomycin
Short Bowel Syndrome (SBS)
Antisecretory Agents
Antimotility Agents
Codeine
Tincture of Opium
Bile Acid Binders
Intestinotrophic Factors
Suggested Reading
Appendix A: Pregnancy and Lactation Labeling Rule
Appendix B: Abbreviations
Index
