Phytochemicals in Soybeans: Bioactivity and Health Benefits

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Soybeans represent an excellent source of high-quality protein with a low content in saturated fat. They can be made into various foods, such as tofu, miso, breakfast cereals, energy bars, and soy cakes. Much research has been carried out on the positive health effects of soybeans, and increasing evidence shows that consumption of soybeans may reduce the risk of osteoporosis, have a beneficial role in chronic renal disease, lower plasma cholesterol, and decrease the risk of coronary heart disease.

Phytochemicals in Soybeans: Bioactivity and Health Benefits describes in detail the chemical characteristics of health-promoting components of soybeans and soybean products, their impacts on human health, and emerging technologies about soybean processing and new products. With 22 chapters containing the most recent information associated with soybean products, topics of the chapters include soybeans’ role in human nutrition and health, their composition and physicochemical properties, action mechanism of their physiologic function, processing engineering technology, food safety, and quality control.

Key Features:

    • Promotes soybean products as functional food with advanced processing technology

    • Presents the basic research containing the experimental design, methods used, and a detailed description of the results.

    • Provides a systematic approach to the subject to facilitate a better comprehension of the subjects with illustrations and diagrams

    • Includes a comprehensive and up-to-date list of references

    With contributions from authors around the world who are experts in their field, this book contains new information on the health impacts of soybean consumption, new product development, and alternative technologies of soybean processing, and will be useful for professors and researchers, as well as graduate and undergraduate students alike.

    Author(s): Yang Li, Baokun Qi
    Series: Functional Foods and Nutraceuticals
    Publisher: CRC Press
    Year: 2022

    Language: English
    Pages: 538
    City: Boca Raton

    Cover
    Half Title
    Series Page
    Title Page
    Copyright Page
    Table of Contents
    Series Editor’s Preface
    Editors’ Preface
    About the Editors
    Contributors
    Chapter 1 Health Perspectives on Soy Isoflavones
    1.1 Introduction
    1.2 Mechanism of Action
    1.2.1 Estrogenic and Anti-Estrogenic Activity
    1.2.2 Antioxidant Activity
    1.2.3 Anti-Inflammatory Activity
    1.2.4 Other Mechanisms
    1.3 Metabolism and Bioavailability
    1.3.1 Bioactive Metabolites
    1.3.2 Intestinal Microbiota Influence
    1.4 Health Effects
    1.4.1 Menopausal Symptoms
    1.4.2 Cancer
    1.4.3 Cardiovascular Disease
    1.4.4 Osteoporosis
    1.4.5 Cognitive Functions
    1.4.6 Diabetes
    1.4.7 Polycystic Ovary Syndrome
    1.4.8 Skin
    1.4.9 Other Effects
    1.5 Sources and Exposure
    1.5.1 Food
    1.5.2 Dietary Supplements
    1.5.3 Infant Formulas
    1.6 Safety Aspects
    1.6.1 Adverse Effects
    1.6.2 Recommendations
    1.7 Concluding Remarks
    Acknowledgment
    References
    Chapter 2 Soybean Isoflavone Profile: A New Quality Index in Food Application and Health
    2.1 Introduction
    2.2 Isoflavone Profile in Soybean Seeds
    2.3 Isoflavones in Soybean Seeds and Their Components
    2.4 Isoflavone Biotransformation upon Germination
    2.5 Isoflavones in Soybean Products
    2.5.1 Isoflavones in Unfermented Products
    2.5.2 Isoflavone Profile as Affected by Fermentation
    2.6 Antioxidant Properties and the New Quality Index in Food Application and Health
    2.7 Summary
    References
    Chapter 3 Bioactive Peptides from Soybeans and Derived Products
    3.1 Introduction
    3.2 Bioactive Peptides from Soybeans and Their Products
    3.3 Characteristics of Bioactive Peptides
    3.4 Purification and Identification of Bioactive Peptides
    3.5 Summary
    References
    Chapter 4 Antioxidant Activity and Health Benefits of Anthocyanin of Black Soybeans
    4.1 Introduction
    4.2 Utilization of Black Soybean
    4.3 Anthocyanin
    4.3.1 Cyanidin 3 Glucoside (C3G)
    4.4 Antioxidant Activity and Health Benefits
    4.4.1 Free Radical Scavenging Activity
    4.4.2 Anti-Inflammatory and Anticancer Activity
    4.4.3 Anti-Atherosclerosis and Coronary Heart Disease
    4.4.4 Antidiabetic Activity
    4.4.5 Anti-Obesity
    4.5 Future Potency
    4.6 Summary
    References
    Chapter 5 Soybean Oil: Chemical Properties and Benefits for Health
    5.1 Introduction
    5.2 Composition of Soybean Oil
    5.2.1 Fatty Acids of Soybean and Their Healthful Properties
    5.2.2 Essential Fatty Acids
    5.2.3 Triacylglycerol Composition
    5.2.4 Soybean Oil of Modified Fatty Acid Composition and Its Health Benefits
    5.3 Nonacylglycerol Components of Soybean Oil: Structure, Occurrence, and Health-Promoting Effects
    5.3.1 Phospholipids
    5.3.1.1 Structure and Technological Relevance
    5.3.1.2 Bioavailability and Health Effects
    5.3.2 Tocopherols
    5.3.2.1 Structure and Occurrence
    5.3.2.2 Antioxidant Mechanism
    5.3.2.3 Bioavailability
    5.3.2.4 Biological Activity and Health-Promoting Effects
    5.3.3 Phytosterols
    5.3.3.1 Structure and Occurrence
    5.3.3.2 Biological Role of Phytosterols
    5.3.4 Other Components
    5.3.4.1 Sphingolipids
    5.3.4.2 Carotenoids
    5.4 Composition and Oxidative Stability of Soybean Oil
    5.4.1 Factors That Influence the Oxidative Stability
    5.4.2 How to Prevent Oil Oxidation and Determine the Oxidative Stability
    5.5 Final Considerations
    References
    Chapter 6 Polyamines in Soybean Food and Their Potential Benefits for the Elderly
    6.1 Introduction
    6.2 Chemical and Biochemical Properties of Polyamines
    6.3 Polyamines and Health in the Elderly
    6.3.1 Mechanism of Action of Polyamines in Aging
    6.3.2 Health Effects of Polyamines Related to Aging‑Associated Pathologies
    6.3.2.1 Neuroprotection by Polyamines
    6.3.2.2 Polyamines in Cardiovascular and Metabolic Syndromes
    6.3.2.3 Polyamines in Muscle-Related Diseases
    6.3.2.4 Effects of Polyamines on Tumorigenesis
    6.4 Polyamines in Soybean and Soy Products
    6.4.1 Soybean and Non-Fermented Soy Products
    6.4.2 Fermented Soy Products
    6.5 Impact of Polyamine Intake from Soybean Food on the Elderly Population
    6.6 Summary
    References
    Chapter 7 Soybean Glyceollins and Human Health
    7.1 Introduction
    7.2 Chemical Structure and Biosynthesis of Soybean Glyceollins
    7.3 Elicitors of Glyceollin Production
    7.4 Absorption and Bioavailability of Glyceollins
    7.5 Health-Promoting Properties of Glyceollin
    7.5.1 Anti-Estrogenic and Anticancer Activities
    7.5.2 Anti-Inflammatory Activities
    7.5.3 Antioxidant Activities
    7.5.4 Effects on Glucose Metabolism
    7.5.5 Effects on Lipid Metabolism
    7.5.6 Effects on Melanogenesis
    7.5.7 Effects on Bone Health
    7.6 Conclusion and Future Direction
    References
    Chapter 8 Soybean Allergens
    8.1 Introduction
    8.2 Soybean Allergy
    8.3 Molecular Characterization and Clinical Relevance of Soybean Allergens
    8.3.1 Gly m 1 and Gly m 2 (Soybean Hull Proteins)
    8.3.2 Gly m 3 and Gly m 4 (Birch-Pollen Related Allergens)
    8.3.3 Gly m 5 (β-Conglycinin) and Gly m 6 (Glycinin)
    8.3.4 Gly m 7 and Gly m 8
    8.3.5 Other Soybean Allergens
    8.4 IgE Cross-Reactivity of Soybean Allergens with Other Species
    8.5 Strategies to Mitigate Soybean Allergenicity
    8.5.1 Effect of Food Processing
    8.5.2 Digestibility
    8.5.3 Genetic Modification
    8.6 Traceability of Soybean Allergens in Processed Foods
    8.7 Conclusions
    Acknowledgments
    References
    Chapter 9 Isolation, Bioactivity, Identification, and Commercial Application of Soybean Bioactive Peptides
    9.1 Introduction to Soybean Bioactive Peptides
    9.1.1 Preparation, Isolation, and Identification of Soybean Bioactive Peptides
    9.1.1.1 Gastrointestinal Digestion
    9.1.1.2 Enzymatic Hydrolysis
    9.1.1.3 Food Processing
    9.1.1.4 Fermentation
    9.1.2 Isolation of Soybean
    9.2 Identification of Soybean Bioactive Peptides
    9.3 Bioactivity Verification of Soybean Peptides
    9.3.1 Hypocholesterolemic
    9.3.2 Antidiabetic
    9.3.3 Antihypertensive
    9.3.4 Anticancer
    9.3.5 Antioxidant and Anti-Inflammatory
    9.3.6 Immunomodulatory
    9.4 Commercial Application of Soybean Peptides
    9.4.1 Nutraceutical
    9.4.2 Functional Food Ingredients
    9.5 Summary
    References
    Chapter 10 Revisiting Side Streams of Soy Product Processing
    10.1 Introduction
    10.2 Okara Valorization
    10.2.1 An Overview of Okara Composition and Bioactive Components
    10.2.2 Enzyme Treatment
    10.2.3 Fermentation
    10.2.3.1 Fungi
    10.2.3.2 Bacteria
    10.2.3.3 Yeasts
    10.2.4 Using Multiple Biocatalysts for Okara Utilization
    10.3 Soy Whey Valorization
    10.3.1 Overview of the Composition of Soy Whey
    10.3.2 Enzymatic Treatment
    10.3.3 Fermentation
    10.3.3.1 Food Fermentation
    10.3.3.2 Fermentation for Non-Food Applications
    10.4 Future Prospects
    10.5 Conclusion
    References
    Chapter 11 Okara: A Soybean By-Product with Interesting Properties in Nutrition and Health
    11.1 Introduction
    11.2 Okara: Definition, World Production, Obtainment, and Chemical Composition
    11.2.1 Definition and World Production
    11.2.2 Okara Obtainment
    11.2.3 Chemical Composition
    11.3 Bioactive Compounds and Health Implications
    11.3.1 Dietary Fiber and Oligosaccharides
    11.3.2 Phenolic Compounds and Isoflavones
    11.3.3 Proteins and Bioactive Peptides
    11.3.4 Health Implications
    11.4 Okara Valorization for Food Uses
    11.4.1 Direct Uses
    11.4.2 Treatments for Okara Valorization
    11.4.2.1 Bioprocessing
    11.4.2.2 Chemical Treatments
    11.4.2.3 Physical Treatments
    11.5 Summary
    References
    Chapter 12 Polysaccharides from Soybean Hulls and Their Functional Activities
    12.1 Soybean Hulls
    12.1.1 Soybean Hulls’ Polysaccharides
    12.1.1.1 Composition of Polysaccharides
    12.1.1.2 Chemical and Molecular Properties
    12.1.1.3 Physiological Functions of Polysaccharides
    12.2 Recovery of Soybean Polysaccharides
    12.3 Soybean-Polysaccharides-Rich Functional Foods
    12.4 Summary
    References
    Chapter 13 Effects of Novel Processing Methods on Structure, Functional Properties, and Health Benefits of Soy Protein
    13.1 Introduction
    13.2 Structure, Functional Properties, and Health Benefits of Soy Protein
    13.3 Effects of Ultrasound Processing on the Structure, Functional Properties, and Health Benefits of Soy Protein
    13.3.1 Effects of HIU on the Structure of Soy Proteins
    13.3.2 Effects of HIU on the Functional Properties of Soy Proteins
    13.3.3 Effects of HIU on the Health Benefits of Soy Proteins
    13.4 Effects of High-Pressure Processing on the Structure, Functional Properties, and Health Benefits of Soy Protein
    13.4.1 Effects of HPP on the Structure of Soy Proteins
    13.4.2 Effects of HPP on the Functional Properties and Health Benefits of Soy Proteins
    13.5 Effects of Irradiation on the Structure, Functional Properties, and Health Benefits of Soy Protein
    13.5.1 Effects of Irradiation on the Structure of Soy Proteins
    13.5.2 Effects of Irradiation on the Functional Properties and Health Benefits of Soy Protein
    13.6 Effects of Microwave Processing on the Structure, Functional Properties, and Health Benefits of Soy Protein
    13.7 Effects of Ohmic Heating on the Structure, Functional Properties, and Health Benefits of Soy Protein
    13.8 Effects of Pulsed Electric Field Processing on the Structure, Functional Properties, and Health Benefits of Soy Protein
    13.9 Cold Plasma Processing on the Structure, Functional Properties, and Health Benefits of Soy Protein
    13.10 Effects of Ultraviolet Processing on the Structure, Functional Properties, and Health Benefits of Soy Protein
    13.11 Conclusion
    References
    Chapter 14 Fermentation of Soybeans – Technology, Nutritional Properties, and Effects
    14.1 Introduction
    14.1.1 Products and By-Products
    14.1.1.1 Products
    14.1.1.2 By-Products
    14.2 Fermentation
    14.2.1 Bacterial Fermentation
    14.2.2 Fungal Fermentation
    14.2.3 Mixed Culture Fermentation
    14.3 Nutritional Improvements during Fermentation
    14.4 Health Benefits of Fermented Soybean
    14.4.1 Bioactive Compounds
    14.4.2 Health Benefits of Traditional Fermented Soy Foods
    14.5 Soybean Meal Fermentation
    14.6 Future Scope
    14.7 Summary
    References
    Chapter 15 Soybean Processing By-Products and Potential Health Benefits
    15.1 Introduction
    15.2 Sources of Soybean Processing By-Products
    15.2.1 Soybean Press Cake and Soybean Meal Derived from Soybean Oil Production
    15.2.2 Soybean By-Product (Okara) Derived from Soy Milk Production
    15.3 Nutrient and Phytochemical Content of Soybean Processing By-Products
    15.3.1 Nutrient Content of Soybean Press Cake and Soybean Meal
    15.3.2 Nutrient Content of Soy Milk By-Product
    15.3.3 Phytochemical Content of Soybean Processing By-Products
    15.4 Potential Health Benefits of Soybean Processing By-Products
    15.4.1 Soybean Processing By-Products as a Rich Source of Fiber for Health Benefits
    15.4.2 Soybean Processing By-Products as a Rich Source of Proteins for Health Benefits
    15.4.3 Soybean Processing By-Products as a Rich Source of Isoflavones for Health Benefits
    15.4.4 Soybean Processing By-Products as a Rich Source of Saponins for Health Benefits
    15.4.5 Other Functional Components from Soybean Processing By-Products for Health Benefits
    15.5 Factors Affecting the Potential Health Benefits of Soybean Processing By-Products
    15.6 Utilization of Soybean Processing By-Products for Functional Foods
    15.6.1 Incorporation of Dried Powders as an Ingredient in Common Food Items
    15.6.2 Utilization as Substrates for Improvement of Health Benefits
    15.7 Conclusion
    References
    Chapter 16 Korean Traditional Fermented Soybean Foods and Their Functionalities
    16.1 Introduction
    16.2 Overall Review of Korean Fermented Soybean Products
    16.2.1 Cultural Background
    16.2.2 The Origin of Soybean
    16.2.3 Raw Materials
    16.2.3.1 Soybean
    16.2.3.2 Rice
    16.2.3.3 Red Pepper
    16.2.3.4 Salt
    16.2.3.5 Meju
    16.2.3.6 Biological Changes during Soybean Fermentation
    16.3 Doenjang
    16.3.1 Introduction
    16.3.2 Preparation Method
    16.3.3 Microorganisms Concerned
    16.3.4 Nutritional Composition
    16.3.5 Functionality and Health Benefits
    16.3.5.1 Anticancer Effect
    16.3.5.2 Antihypertensive Effect
    16.3.5.3 Body Weight Control and Anti-Atherogenic Effects
    16.3.5.4 Boosting Immune System
    16.3.5.5 Antidementia Effect
    16.3.6 Ethnic and Socio-Economic Value
    16.4 Gochujang
    16.4.1 Introduction
    16.4.2 Preparation Method
    16.4.3 Microorganisms Concerned
    16.4.4 Nutritional Composition
    16.4.5 Functionality and Health Benefits
    16.4.5.1 Anticancer Effect
    16.4.5.2 Anti-Obesity Effect
    16.4.5.3 Blood Glucose Control Effect
    16.4.5.4 Atherosclerosis and Cardiovascular Effect
    16.4.5.5 Stress Control and Mitigation (Autonomic Nervous System Stabilization)
    16.4.6 Ethnic and Socio-Economic Value
    16.5 Cheonggukjang
    16.5.1 Introduction
    16.5.2 Preparation Method
    16.5.3 Microorganism Concerned
    16.5.4 Nutritional Composition
    16.5.5 Functionality and Health Benefits
    16.5.5.1 Enhance Digestive Absorption and Nutrients
    16.5.5.2 Antihypertensive Effect
    16.5.5.3 Atherosclerosis and Cardiovascular Effect
    16.5.5.4 Antioxidant Activity
    16.5.5.5 Antidiabetic Activities
    16.5.5.6 Anti-Obesity Activity
    16.5.5.7 Improvement of Intestinal Functions
    16.5.5.8 Immunity Boosting and Anti-Allergic Activity
    16.5.6 Ethnic and Socio-Economic Value
    16.6 Ganjang
    16.6.1 Introduction
    16.6.2 Functionality and Health Benefits
    16.7 Summary
    References
    Chapter 17 Traditional Chinese Fermented Soybean Products and Their Physiological Functions
    17.1 Introduction
    17.2 Douchi
    17.2.1 Processing Technology of Douchi
    17.2.2 The Development of Functional Components of Douchi
    17.2.2.1 Anti-Oxidative Components
    17.2.2.2 Anti-Hypertensive Components
    17.2.2.3 Anti-Inflammatory Components
    17.2.2.4 Components with Anti-α-Glucosidase Activity
    17.3 Sufu
    17.3.1 Processing Technology of Sufu
    17.3.2 The Development of Functional Components of Sufu
    17.3.2.1 Anti-Hypertensive Components
    17.3.2.2 Anti-Oxidative Components
    17.3.2.3 Anti-Inflammatory Components
    17.4 Soy Sauce
    17.4.1 Processing Technology of Soy Sauce
    17.4.2 The Development of Functional Components of Soy Sauce
    17.4.2.1 Anti-Oxidative Components
    17.4.2.2 Immunomodulatory Components
    17.5 Future Trends
    References
    Chapter 18 Value-Added Processing and Function of Okara
    18.1 Introduction
    18.2 Nutritional and Phytochemical Components of Okara
    18.2.1 Dietary Fiber
    18.2.2 Protein
    18.2.3 Fats
    18.2.4 Minerals
    18.2.5 Vitamins
    18.2.6 Isoflavones
    18.3 Okara Processing in the Food Industry
    18.3.1 Processing Technology and Processes
    18.4 New Okara Products
    18.4.1 Baked Foods
    18.4.2 Beverages and Dairy Products
    18.4.3 Fried Puffed Foods
    18.4.4 Meat Products
    18.5 Health-Encouraging Functions of Prebiotic Okara
    18.6 Conclusion
    Acknowledgments
    References
    Chapter 19 Impact of Drying on Isoflavones in Soybean
    19.1 Introduction
    19.2 Drying Principles
    19.3 Some Drying Techniques Applied for Soybean and Soy Products
    19.3.1 Bin Drying
    19.3.2 Vacuum Dryers
    19.3.3 Drum Drying
    19.3.4 Freeze Drying
    19.3.5 Microwave Drying
    19.3.6 Impingement Drying
    19.3.7 Infrared Drying
    19.3.8 Superheated Steam Drying
    19.3.9 Fluidized Bed Drying
    19.3.10 Spray Drying
    19.4 The Changes of Isoflavones During Drying
    19.5 Applications of Drying on Isoflavones in Soybean and Soy Food Products
    19.5.1 Soybean and Soy Food Products
    19.5.2 Soybean Extract
    19.6 Conclusion
    References
    Chapter 20 Soybean-Derived Bioactive Peptides and Their Health Benefits
    20.1 Introduction
    20.2 Soy Proteins
    20.3 Methods for the Production of Soybean-Derived Bioactive Peptides
    20.3.1 Microbial Fermentation
    20.3.2 Gastrointestinal Digestion
    20.3.3 Enzymatic Hydrolysis
    20.3.4 Food Processing
    20.4 Soybean-Derived Bioactive Peptides and Their Bio-Functionality
    20.4.1 Antioxidant
    20.4.2 Antidiabetic
    20.4.3 Antihypertensive
    20.4.4 Anticancer
    20.4.5 Immunomodulatory
    20.4.6 Antimicrobial
    20.4.7 Hypocholesterolemic
    20.5 Future Perspective and Conclusion
    References
    Chapter 21 Fatty Acid Composition in the Soybean Sprout
    21.1 Introduction
    21.2 Soybean Sprouts
    21.3 Comparison of the Nutritional Composition of Soybean Seeds and Sprouts
    21.4 Variation in Fatty Acid Compositions across Different Crops between Seeds and Sprouts
    21.5 Changes in Fatty Acid Levels from Seed to Sprout in Soybean
    21.6 Differences of Fatty Acid Concentration across Soybean Genotypes
    21.7 Changes in Fatty Acid Compositions on Different Sprouting Days
    21.8 Changes in Fatty Acid Compositions Due to Temperature and Light Conditions during Sprouting
    21.9 Soybean Seed Coat Color Affects Fatty Acid Compositions in Soybean Sprouts
    21.10 Genetic Variation of Soybean Germplasm for Soybean Sprouts
    21.11 Environmental Factors Influencing Fatty Acid Compositions in Soybean Seed
    21.12 Breeding Soybean Cultivars with Improved Fatty Acid Compositions in Soybean Sprouts
    21.13 Summary
    Acknowledgments
    References
    Chapter 22 Peptides Derived from High Oleic Acid Soybean and Their Health Benefits
    22.1 Introduction
    22.2 Soybean Seed Composition
    22.3 Methods of Peptide Production from High Oleic Acid Soybean Seed
    22.3.1 In Vitro Enzymatic Hydrolysis
    22.3.2 Food Processing
    22.3.3 Fermentation
    22.4 Preparation and Properties of Soy Peptides
    22.4.1 Preparation of Soymeal and Protein Isolate
    22.4.2 Optimization of Conditions for Enzymatic Hydrolysis with Alcalase
    22.4.3 Preparation of Gastrointestinal Environment Resistant Peptide Hydrolysates
    22.5 Properties of Soy Peptides in General and Health Benefits
    22.5.1 Cholesterol Lowering Peptides
    22.5.2 Anti-Diabetic Soy Peptides
    22.5.3 Antioxidative Peptides from Soybeans
    22.5.4 Anti-Hypertensive Soybean Peptides
    22.5.5 Anticancer Soybean Peptides
    22.5.6 Immunomodulatory Peptides from Soybeans
    22.5.7 Neuromodulatory Peptides from Soybeans
    22.6 Challenges
    22.7 Conclusion
    References
    Index