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Pharmacology of the Contraceptive Steroids

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Reviews the pharmacology of contraceptive steroids providing analyses of the pharmacokinetics and intermediate metabolism of orally administered synthetic progestins and oestrogens and of steroids administered by long-acting injections and implants.

Author(s): Joseph William Goldzieher; Kenneth Fotherby
Publisher: Raven Press
Year: 1994

Language: English
Commentary: From archive.org: https://archive.org/details/pharmacologyofco0000unse
Pages: 463
City: New York

Front Cover
Title Page
Copyright
Contents
Contributors
Preface
Introduction (Potts)
1: The Progestins (Perone)
2: The Estrogens (Goldzieher)
3: Mechanism of Action of Steroid Hormones (Clark)
4: Pharmacokinetics of Selected Contraceptive Steroids in Various Animal Species (Kuhnz & Blode)
5: Metabolism of Contraceptive Steroids in Animals (Stanczyk)
6: Issues in Animal Pharmacology (Edgren)
7: Pharmacokinetics and Metabolism of Progestins in Humans (Fotherby)
8: Pharmacokinetics and Metabolism of Ethynyl Estrogens (Goldzieher)
9: Long-Acting Contraceptives (Primiero & Benagiano)
10: The Hypothalamo-Pituitary-Ovarian System (Goldzieher)
11: The Female Breast (Beller)
12: The Lower Reproductive Tract (Johannisson & Brosens)
13: The Adrenal Gland (Petak & Steinberger)
14: The Thyroid Gland (Goldzieher)
15: The Liver (Sillem & Teichmann)
16: Bone (Notelovitz)
17: Effects on the Skin (Goldzieher)
18: Skeletal Muscle Function (Wirth)
19: Nervous System (Keefe)
20: Cardiovascular System: Blood Pressure (Fraser & Weir)
21: Cardiovascular System: Coagulation, Thrombosis, and Contraceptive Steroids—Is There A Link? (Beller)
22: Cardiovascular System: Contraceptive Steroids, Plasma Lipoprotein Levels, and Coronary Artery Atherosclerosis (Washburn, Wagner, Adams, & Clarkson)
23: Metabolism: Carbohydrate Metabolism (Elkind-Hirsch & Goldzieher)
24: Metabolism: Contraceptive Steroids and Some Plasma Proteins (Cullberg)
25: Metabolism: Vitamins and Trace Elements (Amatayakul)
26: Immunologic Effects of Estrogens, Progestins, and Estrogen-Progestin Combinations (Schuurs, Geurts, Goorissen, Hazes, & Verheul)
27: Teratogenesis and Mutagenesis (Goldzieher)
28: Drug Interactions (Back & Orme)
29: Evaluating Efficacy and Safety (Edelman & Goldzieher)
Appendix: Chemical Nomenclature: Trivial and Chemical Names
Subject Index
Back Cover