Pharmacology Ain Shams

Part 1
1. General Pharmacology
Evaluation Of New Drugs
Pharmacokinetics
Absorption
Distribution
Biotransformation
Excretion
Pharmacodynamics
Mechanism (mode) Of Action
Ligands Binding
Signaling Mechanisms
Dose-response Relationship
Adverse Drug Reactions
Pharmacogenetic Disorders
Drug Allergy
Drug Interactions
Prescription Writing
Autonomic Pharmacology
2. Adrenergic Pharmacology
Drugs Affecting Ne Release
Classification Of Adrenergic Receptors
Sympathomimetic Drugs
Directly Acting Sympathomimetics
Selective B2 Agonists
Selective A1 Agonists
Indirectly Acting Sympathomimetics
Mixed- Or Dual-acting Sympathomimetic Drugs
Choice Of Sympathomimetic Drugs
Beta Adrenoceptor Blockers (bbs)
Alpha Adrenoceptor Antagonists
Specific A Blockers
Centrally- Acting Sympatholytics
3. Cholinergic Pharmacology
Cholinergic Receptors & Ach Actions
Classification Of Cholinomimetics
Choline Esterase Inhibitors
Antimuscarinic Agents
Skeletal Muscle Relaxants
Neuromuscular Blockers (nmbs)
Depolarizing Neuromuscular Blockers
Spasmolytics
4. Autacoids Pharmacology
Histamine
H1- Receptors Blockers (antihistamines)
Serotonin
Migraine And Antimigraine Drugs
Prostaglandins (pgs) And Thromboxanes (txs)
Leukotrienes (lts)
Angiotensin Ii
Kininsl
Platelet-activating Factor (paf)
Part 2
1. Renal Pharmacology
Basic Physiology Of The Kidney
Transport Ofwater &electrolytes In The Nephron
Diuretics
Loop Diuretics
Thiazide Diuretics
Potassium-retaining Diuretics
Osmotic Diuretics
Carbonic Anhydrase Inhibitors (cais)
Drugs And Potassium Homeostasis
Disturbances In K" Serum Level
Magnesium
Treatment Of Idiopathic Hypercalciuria
2. Cardiovascular Pharmacology
Drug Therapy Of Ischemic Heart Diseases
Organic Nitrates
B- Blockers
Calcium Channel Blockers (ccbs)
Other Antianginal Agents
Management Of Ischemic Heart Disease
Drug Therapy Of Heart Failure
Management Of Heart Failure
Other Agents Used In Heart Failure
Individual Drugs Used In Heart Failure
Angiotensin-converting Enzyme Inhibitors
Angiotensin Ii Receptor Blockers
Hydralazine
Sodium Nitroprusside
Diuretics
Beta Blockers
Positive Inotropic Drugs
Dopamine
Dobutamine
Phosphodiesterase Iii Inhibitors
Acute De-compensated Heart Failure (adhf)
Drug Therapy Of Shock
Hypertension
Treatment Strategy
Management Of Resistant Hypertension
Thiazides Diuretics
B-adrenergic Blockers
Angiotensin-converting Enzyme Inhibitors
Choice Of Antihypertensives
Hypertensive Crisis
Drug Therapy Of- Arrhythmia
Antiarrhythmic Drugs
Class I Agents
Class La Agents
Class Lb Agents
Class Ic Agents
Class Ii Agents
Class Iii Agents
Class Iv Agents
Choice Of Antiarrhythmic Drugs
3. Blood Pharmacology
Drug Therapy Of Thrombosis
Anticoagulants
Parentral Anticoagulants
Low- Molecular- Weight Heparins (lmwhs)
Indirect Selective Inhibitor Of Factor Xa: Fondaparinux
Parentral Direct Thrombin Inhibitors
Oral Anticoagulants
Warfarin
Drug Interactions With Warfarin
Newer Oral Anticoagulants
Protocol For Anticoagulation
Antiplatelet Drugs
Classification Of Antiplatelets
Fibrinolytics (thrombolytics)
Drugs Used In Bleeding Disorders
Vitamin K
Fibrinolytic Inhibitors (antiplasmin)
Plasma Fractions
Cryoprecipitate
Drug Therapy Of Anemias
Drug Therapy Of Iron-deficiency Anemia
Drug Therapy Of Megaloblastic Anemia
Vitamin B12
Folic Acid
Drug-induced Blood Disorders
Drug Therapy Of Hyperlipemia
Management Of Hvperlipidemias
Hmg- Coa Reductase Inhibitors (statins)
Bile Acid Sequestrants
Activators Of Lipoprotein Lipase (fibrates)
Inhibitors Of Lipolysis
Ezetimibe
Combination Therapy
Newer Agents For Treatment Of Dvslipidemia
4. Respiratory Pharmacology
Drug Therapy Of Bronchial Asthma|
Drugs Used In Bronchial Asthma
Classification Of Asthma &its Management
Bronchodilators
Adrenoceptor Agonists
Selective B2 Agonists
Non- Selective Adrenoceptor Agonists
Antimuscarinic Drugs
Methylxanthines
Anti-inflammatory Drugs
Glucocorticoids
Leukotriene Pathway Inhibitors
Cromolyn & Nedocromil Sodium
Omalizumab
Management Of Acute Exacerbations
Respiratory Stimulants
Drugs Contraindicated In Bronchial Asthma & Copd
Drug Therapy Of Cough
Nonspecific Drug Therapy Of Cough
Antitussives
Treatment Of Productive Cough
Cough Mixtures And Cold Remedies
5. Gastrointestinal Pharmacology
Drug Therapy Of Acid - Related Git Diseases
Drug Therapy Of Peptic Ulcer
Anti - Secretory Drugs
Proton Pump Inhibitors (ppis)
H2- Receptor Antagonists
Mucosal Protectives
Sucralfate
Misoprostol
Colloidal Bismuth
Anti- H. Pylorie Drug Therapy
Antacids
Gastroesophageal Reflux Disease (gerd)
Drug Therapy Of Vomiting
Antiemetic Drugs
Drug Therapy Of Diarrhea
Antidiarrheal Agents
Idrug Therapy Of Constipationi
Irritable Bowel Syndrome
Hepatic Encephalopathy
Drug Therapy Of Esophageal Varices
Part 3
1. Endocrine Pharmacology
Clinically Important Hypothalamic Hormones
Anterior Pituitary Hormones
Posterior Pituitary Hormones
Insulin &oral Antidiabetic Drugs
Insulin
Diabetes Mellitus
Drug Therapy Of Diabetes
Insulin Therapy
Oral Antidiabetics
Insulin Secretagogues
Sulfonylureas
Nonsulfonylureas Secretagogues1
Insulin Sensitizers
Biguanides
Thiazolidinediones
Alpha Glucosidase Inhibitors
Sodium-glucose Co-transporter 2 Inhibitors
Dipeptidyl Peptidase (dpp)-4 Inhibitors
Subcutaneous Antidiabetics
Glp-1 Receptor Agonists
Amvlin Analogues
Management Of Diabetes
Comas In Diabetes
Agents Affecting Bone Calium Homeostasis
Endogenous Agents
Vitamin D
Parathyroid Hormone (pth)
Calcitonin
Estrogens
Glucocorticoids
Exogenous Agents
Bisphosphonates
Raloxifene
Denosumab
Strontium
Cinacalcet
Fluoride
Thiazides
Disturbances In Calcium Homeostasis & Their Management
Thyroid Hormones And Antithyroid Drugs
Anti-thyroid Drugs
Thionamides
Iodide Salts And Iodine
Radioactive Iodine
B- Adrenoceptive Blockers
Thyroid Crisis Or Storm
Corticosteroids
Sex Hormones
Synthetic Estrogens
Synthetic Progestins
Oral And Implantable Contraceptives
Partial- Agonist Estrogens And Progestins
Antiprogestins
Ovulation- Inducing Agents (in Treatment Of Infertility)
Androgens
Anabolic Steroids
Antiandrogens
2. Chemotherapy
Antibacterial Chemotherapy
Inhibitors Of Cell Wall Synthesis
Beta- Lactam Antibiotics
Penicillins
Cephalosporins & Cephamycins
Other B-lactam Antibiotics
B -lactamase Inhibitors: Clavulanic Acid & Sulbactam
Vancomycin
Telavancin
Teicoplanin
Antimicrobials Disrupting Cell Membranes
Daptomycin
Inhibitors Of Protein Synthesis
Tetracyclines
Aminoglycosides
Macrolides
Clindamycin
Chloramphenicol
Streptogramins
Oxazolidinones
Inhibitors Of Nucleic Ach) Synthesis
Quinolones
Rifampicin (rifampin)
Folate- Antagonists
Sulfonamides
Trimethoprim
Co-trimoxazole
Nitrofurantoin
Anti - Tuberculous Drugs
Isoniazid
Rifampicin:
Pyrazinamide
Ethambutol
Antileprotic Drugs
Rifampicin:
Dapsone
Clofazimine
Clinical Aspectsofantimicrobials
Antimicrobial Drug Combinations
Choice Of Antimicrobials
Drug Therapy Of Amebiasis
Luminal Amebecides
Tissue Amebecides
Metronidazole
Chloroquine
Drug Therapy Of Malaria
Antifungal Drugs
Amphotericin- B
Flucytosine
Azoles
Caspofungin
Griseofulvin
Terbinafine
Nystatin
Antiviral Drugs
Mechanism Of Action & Indications Of Antiviral Drugs
Anti-viral Agents For Hcv
Interferon
Ribavirin
Newer Agents
Interferons
Drug Therapy Of Helminthic Infections
Cytotoxic Drugs
3. Immunopharmacology
Immunosuppressants
Immunostimulants
Drug Therapy Of Rheumatoid Arthritis
Disease-modifying Antirheumatic Drugs
Management Ofsle
Disease-modifying Treatment Ofmultiple Sclerosis (ms)
4. Nsaids &gout Therapy
Acetylsalicylic Acid (aspirin)
Non Selective Nsaids
Selective Cox-2 Inhibitors
Paracetamol (acetaminophen)
Drug Therapy Of Gout
5. Cns Pharmacology
Analgesics
Opioid (narcotic) Analgesics
Pure Agonists
Partial Agonists
Pure Opioid Antagonists
Anxiolytics And Sedative- Hypnotics
Barbiturates
Benzodiazepines
General Guidelines For Theranv With Sedative-hypnotics
Antidepressants
Maois
Other Antidepressants
Guidelines For The Use Of Antidepressants
Antipsychotic Drugs (neuroleptics)
Typical Antipsychotics
Extrapyramidal Side Effects
Atypical Antipsychotics
Lithium Carbonate
Drug Therapy Of Epilepsy
Choice Of Antiepileptic Drugs In Different Types Of Epilepsy
General Guidelines For Antiepileptic Drug Therapy
Management Ofstatus Epilepticus
Antiparkinsonian Drugs
Dopaminergic Drugs
Anticholinergics
Choice Of Drugs In Early Disease
Management Of Motor Complications In Advanced Parkinson's Disease
Drug Therapy Of Alzheimer's Disease
Drug Abuse
General Anesthetics
Inhalation Anesthetics
Intravenous Anesthetics
Local Anesthetics
Management Of Pain
References