This book presents in a consistent format data on ~50 PET radiopharmaceuticals in clinical use. Parameters include basic chemical data, normal biodistribution and excretion, activity administered, radiation dosimetry, patient preparation, and clinical utility, together with a few key references. In some cases a representative image is presented. The organisation is first by clinical specialty (oncology, cardiology, neurology) and within each section by radionuclide (F-18, C-11, etc).
This book will be of interest mostly to nuclear medicine physicians and trainees, but also to a wider medical community including radiologists, oncologists and radiotherapists.
Author(s): James R. Ballinger
Series: Clinicians’ Guides to Radionuclide Hybrid Imaging
Publisher: Springer
Year: 2022
Language: English
Pages: 142
City: Cham
Acknowledgement
Introduction
Contents
Part I: Oncology—18F-Labelled Agents
18F-Fluorodeoxyglucose (FDG)
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
Sodium 18F-Fluoride (NaF)
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
18F-Fluorothymidine (FLT)
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Fluoromethylcholine
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
18F-Fluoroethylcholine (FECh)
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Fluoroethyltyrosine (FET)
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Fluoromisonidazole (FMISO)
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Fluoroazomycin Arabinoside (FAZA)
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Fluoroerythronitroimidazole (FETNIM)
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-HX4
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Fluciclatide
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Galacto-RGD
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Fluciclovine (FACBC)
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-ICMT11
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-DCFPyL
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-PSMA-1007
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Tetrafluoroborate
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
Part II: Oncology—11C-Labelled Agents
11C-Acetate
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
11C-Choline
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
11C-Methionine
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
Part III: Oncology—68Ga-Labelled Agents
68Ga-DOTATOC
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
68Ga-DOTATATE
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
68Ga-HA-DOTATATE
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
68Ga-DOTANOC
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
68Ga-DKFZ-PSMA-11
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
68Ga-THP-PSMA
Route of Synthesis
Normal Biodistribution and Excretion (Fig. 1)
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Example Image
Further Reading
68Ga-NOTA-RGD
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
68Ga-NODAGA-RGD
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
68Ga-DOTA-Zoledronate
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
68Ga-DOTA-Bombesin
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
68Ga-NOTA-Bombesin
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
68Ga-FAPI
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
Part IV: Oncology—Other Agents
Sodium 124I-Iodide
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
124I-MIBG
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
64Cu-DOTATATE
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
Part V: Cardiology—18F-Labelled Agents
18F-Flurpiridaz
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-FTPP
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-FCPHA
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Flubrobenguane
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
Part VI: Cardiology—Other Agents
11C-Acetate
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
13N-Ammonia
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
15O-Water
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
Rubidium-82
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
Part VII: Neurology—18F-Labelled Agents
18F-Florbetapir
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Florbetaben
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Flutemetamol
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-Flortaucipir
Route of Synthesis
Normal Biodistribution and Excrtetion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
References
18F-Fallypride
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-FluoroDOPA
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-FE-PE2I
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
18F-FP-DTBZ
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
Part VIII: Neurology—11C-Labelled Agents
11C-Raclopride
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
11C-PiB
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
Part IX: Neurology—15O-Labelled Agents
15O-Water
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
15O-Oxygen
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
15O-Carbon Monoxide
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
15O-Carbon Dioxide
Route of Synthesis
Normal Biodistribution and Excretion
Activity Administered
Radiation Dosimetry
Patient Preparation
Clinical Utility
Further Reading
