This book discusses the history, physics, fundamental principles, sensing technologies, and characterization of plasmonic phenomenon-based fiber-optic biosensors, using optic-plasmonic sensors as a case study. It describes the plasmonic phenomenon and its application in optical fiber-based sensing, presented based on properties and usage of different nanomaterials spread across nine chapters. Content covers advances in nanomaterials, structural designing, and their scope in biomedical applications. Future developments of biosensing devices and related articulate methods are also described.
Features
Gives a comprehensive view on the nanomaterials used in plasmonic optical fiber biosensors.
Includes synthesis, characterization, and usage for detection of different analytes.
Discusses trends in the design of wavelength-based optical fiber sensors.
Reviews micro- and nanostructured biosensing devices.
Explores application of plasmonic sensors in the biosensing field.
This book is aimed at researchers and graduate students in Optical Communications, Biomedical Engineering, Optics, Sensors, Instrumentation, and Measurement.
Author(s): Santosh Kumar, Niteshkumar Agrawal, Chinmoy Saha, Rajan Jha
Publisher: CRC Press
Year: 2022
Language: English
Pages: 296
City: Boca Raton
Cover
Half Title
Title
Copyright
Contents
Author Biographies
Preface
Acknowledgments
Chapter 1 Fundamentals of Plasmonics Sensors
1.1 Introduction
1.2 Fundamentals of Fiber-Optic Sensors and Related Concepts
1.2.1 Total Internal Reflection and Evanescent Wave
1.2.2 Surface Plasmons
1.2.2.1 Definition of Surface Plasmon
1.2.2.2 Brief History of Surface Plasmons
1.2.3 Generation of Propagating Surface Plasmons by Light Using Thin Metallic Film
1.3 Kretschmann’s Configuration
1.4 Transfer Matrix Method
1.4.1 Calculation of Reflected Intensity
1.4.1.1 Boundary Condition at Interface 1
1.4.1.2 Boundary Condition at Interface 2
1.4.2 Transmitted Power through Optical Fiber
1.5 Plasmon Excitation Using Optical Fiber
1.6 Excitation of Localized Surface Plasmon by Light Using Metallic Nanoparticles
1.6.1 Mie Theory
1.7 Fiber-Optic LSPR Sensor Using Metallic Nanoparticles
1.7.1 Refractive Index Dependence
1.8 Fiber-Optic Plasmonic Biosensing Technique
1.8.1 Surface Plasmon Resonance Sensor
1.9 Performance Parameters of Sensors
1.9.1 Sensitivity
1.9.2 Selectivity
1.9.3 Stability
1.9.4 Limit of Detection
1.9.5 Reproducibility
1.9.6 Response Time
1.9.7 Linearity
1.10 Overview of the Book
References
Chapter 2 Important Nanomaterials for Optical Fiber Plasmonic Biosensors
2.1 Introduction
2.2 Basics of Nanomaterial and Its Growing Applications
2.3 Types of Nanomaterial
2.3.1 Metal Nanoparticles
2.3.2 Metal Nanorods and Nanotriangles
2.3.3 Semiconductor Nanoparticles
2.3.4 Carbon-Based Nanoparticles
2.3.5 Polymeric Nanoparticles
2.3.6 Ceramic Nanoparticles
2.3.7 Perovskite Nanoparticles
2.3.8 MXene-Based Nanocomposites
2.3.9 Lipid-Based Nanoparticles
2.4 Synthesis of Nanomaterials
2.4.1 Wet Chemical Method
2.4.2 Physical Method
2.4.3 Exfoliation Method
2.5 Characterization of Nanomaterials
2.5.1 Morphological Characterizations
2.5.2 Structural Characterizations
2.5.3 Surface Area and Particle Size Characterization
2.5.4 Optical Characterizations
2.6 Summary and Conclusion
References
Chapter 3 Design Methodology
3.1 Introduction
3.2 Structural Developments
3.2.1 Tapered Structure
3.2.2 Hetero-Core Structure
3.2.3 Other Structures
3.3 Nanocoating Process and Characterization
3.4 Sensor Development and Applications
3.4.1 Biomedical and Diagnostic Applications
3.4.1.1 Glucose Detection
3.4.1.2 Cholesterol Detection
3.4.1.3 Bacteria Detection
3.4.1.4 Virus Detection
3.4.1.5 Cell Detection
3.4.1.6 DNA Biomolecules Detection
3.4.2 Environmental Applications
3.4.3 Miscellaneous Applications
3.5 Summary and Conclusion
References
Chapter 4 Gold Nanoparticles Assisted Optical Fiber-Based Plasmonic Biosensors
4.1 Introduction
4.2 Synthesis, Characterization, Properties, and Applications of Gold Nanoparticles
4.2.1 Turkevich Method
4.2.2 Brust Method
4.2.3 Seeded Growth Method
4.2.4 Electrochemical Method
4.2.5 Miscellaneous Methods
4.3 Some Biosensor Design Based on AuNPs
4.4 Recent Development of Gold Nanoparticles Assisted Plasmonic Biosensors
4.4.1 Gold Nanoparticles Assisted Glucose Sensor
4.4.2 Gold Nanoparticles Assisted Cholesterol Sensor
4.4.3 Gold Nanoparticles Assisted Other Important Biosensors
4.4.4 Gold Nanoparticles Assisted Biosensors for Bacteria and Virus Detection
4.4.5 Gold Nanoparticle-Based Sensor for Dengue Immunoassay
4.4.6 Gold Nanoparticles Assisted Biosensors for DNA/RNA and Cells Detection
4.5 Summary and Conclusion
References
Chapter 5 Silver Nanoparticles Assisted Optical Fiber-Based Plasmonic Biosensors
5.1 Introduction
5.2 Synthesis, Characterization, Properties, and Applications of Silver Nanoparticles
5.2.1 Synthesis Methods for Silver Nanoparticles and Composites
5.2.1.1 Spherical Silver Nanoparticles
5.2.1.2 Triangular Silver Nanoparticles
5.2.1.3 Synthesis of PVA-AgNPs Composites
5.2.1.4 Green Synthesis of Ag Nanoparticles
5.2.1.5 Synthesis of AgNPs Using Green Route Method
5.3 Diverse Usage of Silver Nanoparticles
5.3.1 Silver Nanoparticles Assisted Biosensors for Biomolecules Detection
5.4 Summary and Conclusion
References
Chapter 6 Graphene Oxide Coated Gold Nanoparticles-Based Fiber-Optic LSPR Sensor
6.1 Introduction
6.2 Experimental Section
6.2.1 Synthesis of AuNPs and GO
6.2.2 Preparation of GO Encapsulated AuNPs
6.2.3 Preparation of Fiber Probe
6.3 Results and Discussion
6.4 Micro-Ball Fiber Sensor Probe Based Uric Acid Biosensor
6.4.1 Fabrication of Micro-Ball Fiber Structure
6.4.2 Experimental Setup
6.4.3 Characterization of Gold Nanoparticles and Graphene Oxide
6.4.4 Detection of Uric Acid Solutions
6.4.5 Sensitivity, Linearity, and Detection Limit of Sensor
6.4.6 Selectivity of Sensor
6.4.7 Analysis of Uric Acid in Human Serum
6.5 Novel Periodically Tapered Structure-Based Sensor to Detect Ascorbic Acid
6.5.1 Design Consideration and Fabrication of Proposed Sensors
6.5.2 Detection of Ascorbic Acid
6.6 Summary and Conclusion
References
Chapter 7 Fiber-Optic LSPR Sensor Using Graphene Oxide Coated Silver Nanostructures
7.1 Introduction
7.2 Experimental Section
7.2.1 Synthesis of AgNPs, GO, and Preparation of GO-Coated AgNPs
7.2.2 Preparation of Fiber Sensing Probe
7.3 Results and Discussion
7.4 AgNPs and GO-Based Plasmonic Sensor for L-Cysteine Detection
7.4.1 Synthesis of Silver Nanoparticles
7.4.2 Experimental Setup and Results
7.5 Summary and Conclusion
References
Chapter 8 Novel Nanomaterials Assisted Optical Fiber-Based Plasmonic Biosensors
8.1 Introduction
8.2 Nanomaterial Synthesis Process
8.2.1 Synthesis Process of AuNPs
8.2.2 Synthesis of AgNPs Solution
8.2.3 Synthesis Process of MXene
8.2.4 Synthesis Process of MoS2-NPs
8.2.5 Synthesis Process of CeO2-NPs
8.2.6 Synthesis Process of GO
8.2.7 Synthesis Process of Colloidal CuO-NPs Solution
8.3 Characterization of Nanoparticles
8.4 Immobilization of Nanoparticles Over the Optical Fiber Probe
8.4.1 Fabrication of AuNPs/ZnO-NPs-Based Optical Fiber Probe
8.4.2 Fabrication of CuO-NPs-Based Optical Fiber Probe
8.4.3 Fabrication of ZnO-NPs/PVA-AgNPs-Based Optical Fiber Probe
8.4.4 Fabrication of MoS2-NPs/AuNPs-Based Optical Fiber Probe
8.5 Detection of Various Biomolecules
8.5.1 SMF-MCF-MMF-SMF Structure Based LSPR Biosensor for Creatinine Detection
8.5.2 Multicore Tapered Fiber Structure-Based Sensor for Creatinine Detection in Aquaculture
8.5.3 Taper-in-Taper Fiber Structure-Based LSPR Sensor for Alanine Aminotransferase Detection
8.5.4 Taper Fiber-Based Sensor for Water Pollutants p-Cresol Detection
8.5.5 MPM Fiber Structure Sensor Probe for cTnI
8.5.6 Hetero-Core Fiber Structure-Based Cardiac Troponin I Detection
8.5.7 Multicore Fiber Biosensor for Acetylcholine Detection
8.5.8 Tapered Optical Fiber Based LSPR Biosensor for Ascorbic Acid Detection
8.5.9 Core Mismatch MPM/SPS Probe-Based Sensor for Cholesterol Detection
8.5.10 CuO and AgNPs Modified SMSMS Structure Probe for Uric Acid Detection
8.5.11 Structure of Optical Fiber Mach-Zehnder Interferometer for Collagen IV Detection
8.6 Summary and Conclusion
References
Chapter 9 Optical Sensors for Detection of Microorganisms
9.1 Introduction
9.2 SPR-Based Sensors
9.3 LSPR-Based Sensors
9.4 Multicore Fiber Sensor for Cancer Cells Detection
9.4.1 Material and Method
9.4.1.1 Material
9.4.1.2 Fabrication of the Sensor Probe
9.4.1.3 Etching of SMF-MCF Structure
9.4.1.4 Characterization
9.4.1.5 Synthesis of Graphene Oxide/Gold Nanoparticles/Copper Oxide Nanoflowers
9.4.1.6 Immobilization of GO/AuNPs/CuO-NFs Over SMF-MCF Structure
9.4.1.7 Cell Culture
9.4.1.8 Experimental Setup
9.4.2 Results and Discussion
9.4.2.1 Optimization of Bare Sensor Structure
9.4.2.2 Characterization of Nanomaterials
9.4.2.3 Characterization of Nanoparticles Coated Sensor Probes
9.4.2.4 Detection of Cancerous Cells
9.4.2.5 Analysis of Reusability, Selectivity, and Anti-Interference Ability
9.4.2.6 Performance Comparison
9.5 Multicore Fiber Probe for Selective Detection of Shigella Bacteria
9.5.1 Materials and Methods
9.5.1.1 Fabrication of Sensor Probe
9.5.1.2 Synthesis of AuNPs and MoS2-NPs
9.5.1.3 Immobilization of AuNPs and MoS2-NPs Over MCF-SMF Sensor Probe
9.5.1.4 LSPR Measurements
9.5.1.5 Culture of Shigella sonnei Bacteria
9.5.2 Results and Discussion
9.5.2.1 Characterization of Nanoparticles
9.5.2.2 Characterization of a Nanoparticles-Coated Sensor Probe
9.5.2.3 LSPR Sensing Results
9.5.2.4 Comparison with Existing Shigella Biosensors
9.6 Summary and Conclusions
9.7 Future Perspective
References
Index
