Author(s): Faris Farassati
Year: 2012
Language: English
Pages: 305
Cover......Page 1
Novel Therapeutic Concepts in Targeting Glioma......Page 2
©......Page 3
Contents......Page 5
Preface......Page 8
Part 1 Surgical Therapy of Glioma......Page 10
1 Innovative Surgical Management of Glioma......Page 12
Part 2 EGFR and Glioma Therapy......Page 34
2 Advances in the Development of EGFR Targeted Therapies for the Treatment of Glioblastoma......Page 36
3 Future Perspectives of Enhancing the Therapeutic Efficacy of Epidermal Growth Factor Receptor Inhibition in Malignant Gliomas......Page 52
Part 3 MicroRNAs in Treatment of Glioma......Page 66
4 MicroRNA and Glial Tumors: Tiny Relation with Great Potential......Page 68
5 The Role of microRNAs in Gliomas and Their Potential Applications for Diagnosis and Treatment......Page 84
Part 4 Inhibition of Invasion in Treatment of Glioma......Page 98
6 Molecular Targets: Inhibition of Tumor Cell Invasion......Page 100
Part 5 Blood-Brain Barrier in Glioma Therapy......Page 118
7 Blood-Brain Barrier and Effectiveness of Therapy Against Brain Tumors......Page 120
Part 6 Gene Therapy of Glioma......Page 150
8 Glioma-Parvovirus Interactions: Molecular Insights and Therapeutic Potential......Page 152
9 The Potential and Challenges of siRNA-Based Targeted Therapy for Treatment of Patients with Glioblastoma......Page 170
10 Hypoxia Responsive Vectors Targeting Astrocytes in Glioma......Page 208
Part 7 LGI1 in Treatment of Glioma......Page 226
11 The Tumor Suppressor Function of LGI1......Page 228
Part 8 Antioxidant Adaptive Response in Glioma......Page 254
12 Antioxidant Adaptive Response of Malignant Glioma Related to Resistance to Antitumor Treatment......Page 256
Part 9 TRP Channels in Glioma Therapy......Page 272
13 Ionic Channels in the Therapy of Malignant Glioma......Page 274
