This book presents recent reports of total syntheses involving a photocatalytic reaction as a key step in the methodology. Modern photocatalysis has proven its generality for the development and functionalization of native functionalities. To date, the field has found broad applications in diverse research areas, including the total synthesis of natural products. Among the selected examples presented in this book, it highlights how the photocatalytic process proceeds in a highly chemo-, regio-, and stereoselective manner, thereby allowing the rapid access to structurally complex architectures under light-driven conditions.
Author(s): A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M Dirsch
Series: Progress in the Chemistry of Organic Natural Products, 120
Publisher: Springer
Year: 2023
Language: English
Pages: 111
City: Cham
About This Book
Contents
Contributors
Modern Photocatalytic Strategies in Natural Product Synthesis
1 Introduction
1.1 Fundamentals of Photocatalysis
1.2 Photocatalysts Used in Total Syntheses—Experimental
2 Radical Cyclizations
2.1 Cyclizations of Carbon-Centered Radicals
2.2 Cyclizations of Nitrogen-Centered Radicals
2.3 Other C–C and C–N Bond-Forming Cyclization Reactions
3 Cycloadditions
3.1 (2 + 2) Cycloadditions
3.2 (4 + 2) Cycloadditions
3.3 (3 + 2) Cycloadditions
3.4 (2 + 2 + 2) Cycloadditions
4 Radical Intermolecular Additions
4.1 Additions of Carbon-Centered Radicals to Alkenes
4.2 Additions of Carbon-Centered Radicals to Arenes or Hetarenes
5 Miscellaneous
5.1 Carbon–Carbon Bond Fragmentations
5.2 Reductive Dehalogenation and Decarboxylation
5.3 Mesolytic Cleavage
5.4 Oxidative Dehydrogenation
6 Concluding Remarks
References
