Landmark Experiments in Protein Science

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Proteins are the workhorses of cells, performing most of the important functions which allow cells to use nutrients and grow, communicate among each other, and importantly, die if aberrant behavior is detected. How were proteins discovered? What is their role in cells? How do dysfunctional proteins give rise to cancers? Landmark Experiments in Protein Science explores the manner in which the inner workings of cells were elucidated, with a special emphasis on the role of proteins. Experiments are discussed in a manner as to understand what questions were being asked that prompted the experiments and what technical challenges were faced in the process; and results are presented and discussed using primary data and graphs.

Key Features

    • Describes landmark experiments in cell biology and biochemistry.

    • Discusses the "How" and "Why" of historically important experiments.

    • Includes primary, original data and graphs.

    • Emphasizes biological techniques, that help understand how many of the experiments performed were possible.

    • Documents, chronologically, how each result fed into the next experiments.

    Author(s): Pascal Leclair
    Publisher: CRC Press
    Year: 2023

    Language: English
    Pages: 252
    City: Boca Raton

    Cover
    Half Title
    Title Page
    Copyright Page
    Dedication
    Contents
    Preface
    Acknowledgments
    About the Author
    Chapter 1: Prelude to Biology: A History of Chemistry
    Chapter 2: The Cell and Heredity
    Chapter 3: Discovery of Proteins and Enzymes
    Chapter 4: Protein and DNA Subunits
    Chapter 5: The Energy of Cells Part I: Glycolysis and the Krebs Cycle
    Chapter 6: Protein and DNA Structure
    Chapter 7: Protein Synthesis Part I: Localization of Protein Translation
    Chapter 8: Protein Synthesis Part II: The Mechanism of Protein Translation
    Chapter 9: The Energy of Cells Part II: Oxidative Phosphorylation
    Chapter 10: The Energy of Cells Part III: The Mechanism of ATP Synthesis
    Chapter 11: Techniques
    Chapter 12: Cell Signaling Part I: The Role of Phosphorylation
    Chapter 13: Cell Signaling Part II: G-protein-coupled Receptors
    Chapter 14: The Secretory Pathway
    Chapter 15: The Mechanism of Cell Death
    Chapter 16: The Biology of Cancer
    Index