Jan Gösta Waldenström and His World : The Life and Work of a Giant in Science, Medicine and Humanity

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Author(s): Frank Wollheim
Publisher: Springer Nature
Year: 2023

Language: English

Foreword by Robert A. Kyle
Foreword by Giampaolo Merlini
Preface
References
Acknowledgements
Contents
1 A Family of Pioneers
References
2 Childhood in Stockholm and Student Years in Uppsala
References
3 The Red Urine Story
3.1 A Diagnostic Triumph
3.2 The First Publication
3.3 Hans Fischer in Munich
3.4 In Munich with a Rockefeller Stipend
3.5 Back in Sweden
3.6 The Doctoral Thesis
References
4 Letters to a Special Friend
Reference
5 Assistant Professor in Uppsala
5.1 Early Hematology Research
5.2 The Growing Family
References
6 Two New Diseases
6.1 Uppsala, A Mecca of Physical Chemistry
6.2 The Svedberg and the Ultracentrifuge
6.3 Electrophoresis and Arne Tiselius
6.4 Purpura Hyperglobilinemia
6.5 Macroglobulinemia
References
7 Exploring Medical Science in Wartime America
7.1 Through Mined Waters to New York City
7.2 Exploring Science in New York City
7.3 Boston, “The Medical Capital of America”
7.4 Washington University in St. Louis
7.5 The University of Minnesota in Minneapolis
7.6 The Mayo Clinic in Rochester
7.7 Final Comments
References
8 Turbulent Final Years in Uppsala
8.1 Selecting a New Professor and Chairman
8.2 The Winner in Uppsala
8.3 The “Looser”
References
9 “The Great Faculty” in Lund
9.1 Introduction
9.2 Pathology and Bacteriology
9.3 Anatomy and Histology
9.4 Physiology, Medical Chemistry, and Pharmacology
9.5 The Department of Medicine
References
10 Malmö General Hospital—MAS
10.1 The Early Years
10.2 The Next Generation
10.3 Medicine
References
11 Arrival in Malmö
11.1 The Department of Medicine
11.2 Department of Surgery
11.3 Obstetrics and Gynecology
11.4 Orthopedic Surgery
11.5 Pathology and Bacteriology
References
12 Autoimmune Hepatitis
12.1 The German Society for Digestive and Metabolic Diseases—DGVS
12.2 The 15th Congress of the DGVS
12.3 A New Liver Disease
References
13 A Charismatic Leader
13.1 The Commander-in-Chief
13.2 The Early Team
13.3 New Routines
13.4 Exciting the Medical Students
References
14 The Carcinoid Syndrome
14.1 The Discovery
14.2 Intestinal Carcinoid
14.3 A Meeting in Malmö
14.4 Clinical Features
14.5 From Bedside to the Bench
14.6 Recent Contributions in the Carcinoid Syndrome
References
15 Beginning of a Golden Age
15.1 The New Wing
15.2 Radiology
15.3 Pathology
15.4 The First Ph.D. Students
15.5 Private Life
References
16 Gammopathies—Jewel in the Crown
16.1 A New Family
16.2 The Harvey Lecture “Gammopathies”
16.3 Monoclonal and Polyclonal Gammopathy
16.4 Epidemiology of Gammopathies
16.5 The Värmland Study
16.6 Genetics of Monoclonal IgM
16.7 MGUS, SMM, and MM
16.8 Familial Autoimmunity
References
17 Porphyria Research from Malmö
17.1 Introduction
17.2 The Porphyrin Diseases as Inborn Errors of Metabolism
17.3 Enter Birgitta Haeger-Aronsen
17.4 Neuropsychiatry and Genetics of Porphyria
17.5 Diabetes Insipidus
17.6 Pathogenesis of Porphyria and Its Rational Therapy
References
18 Inga Marie Nilsson—“The Queen of Coagulation”
18.1 A Rising Star Getting Help from Stockholm
18.2 Erik Jorpes
18.3 The Doctoral Thesis of Inga Marie Nilsson
18.4 Anti-hemophilic Globulin
18.5 Early Use of Cohn Fraction I-0 (AHF) in Von Willebrand’s Disease
18.6 Hemophilia in Sweden
18.7 Professor of Coagulation Research
18.8 Factor VIII Bypass with Activated Factor VII
18.9 A Royal Bleeding Condition
18.10 The Legacy
References
19 Carl-Bertil Laurell and His Outstanding Laboratory of Clinical Chemistry
19.1 Introduction
19.2 Carl-Bertil Laurell in Uppsala
19.3 Carl-Bertil Laurell in Lund
19.4 Carl-Bertil Laurell Arrives in Malmö
19.5 Alpha-1 Antitrypsin Deficiency
References
20 The Division of Cardiology
20.1 The Period 1950–8
20.2 Bengt W. Johansson as Leader
20.3 Concluding Comment
References
21 Bengt Skanse and Endocrinology in Malmö
21.1 Bengt Skanse
21.2 Thyroid Diseases
21.3 Other Contributions
21.4 Aldosterone
21.5 Continued Growth of Endocrinology
21.6 The Tragedy
21.7 Endocrinology After Bengt Skanse
References
22 Hematology
22.1 The International Society of Hematology
22.2 Hematology Research in Malmö
22.3 Concluding Remarks
References
23 A Friendship with Bertel von Bonsdorff
23.1 Bertel von Bonsdorff
23.2 All Light Comes From the East
23.3 The Friendship and the Letters
23.4 The Bertel von Bonsdorff Festschrift in 1964
23.5 The Jan Waldenström Festschrift in 1966
23.6 ISA, The International Society of Amyloidosis
References
24 Visitors and Visits
24.1 Introduction
24.2 VIIth International Congress of Internal Medicine 1962
24.3 Partners in Progress
24.4 Visitors to Malmö
24.5 Two Very Special Visitors
References
25 The Nobel Symposium on Gamma Globulins
25.1 Nobel Symposia
25.2 The First Day: Structure of Gamma Globulins
25.3 Day 2. Structure and Heterogeneity of Gamma Globulins
25.4 Day 3. A Visit to Uppsala
25.5 Day 4. Control of Biosynthesis
25.6 Days 4–5. Clinical Aspects on Control of Gamma Globulin Synthesis
25.7 The Take Home Message
References
26 Emeritus Professor of Medicine
26.1 The Farewell Lecture
26.2 JW’s Private Practice
26.3 Editor of Acta Medica Scandinavica
References
27 New Activities in Stockholm
27.1 Skandia International Symposia
27.2 Radiumhemmet, Jerzy Einhorn, and Oncology in Sweden
27.3 The THX Doctor
References
28 Jan Waldenström. An Esteemed Globetrotter
28.1 A Popular Visitor
28.2 The Jahre Prize
28.3 Other Honors
28.4 Fogarty Scholar at NIH in 1978
28.5 At Home
28.6 Concluding Remark
References
29 Macroglobulinemia—An Update
29.1 1984—The 40th Anniversary
29.2 Significant News from the Bing Center for Waldenström’s Macroglobulinemia
29.3 10th International Workshop on Waldenström’s Macroglobulinemia
29.4 Macroglobulinemia Then and Now, a Success Story
References
30 Happy Years
30.1 A Man with Temperament
30.2 JW More Private
30.3 The 80th Birthday at Torup Castle
References
31 The Final Years
31.1 The Last Decade
31.2 The Legacy
References
Author Index