Human Genetics: Concepts and Applications

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ISBN: 9781260570465 is the International edition of Human Genetics 13th Edition by Ricki Lewis. This ISBN is student textbook only. It does not come with online access code. Access code, if required by an instructor, sold separately at another ISBN. The content of International edition is the same as other formats. Today, human genetics is for everyone. It is about variation more than about illnesses, and increasingly about the common rather than about the rare. Once an obscure science or an occasional explanation for an odd collection of symptoms, human genetics is now part of everyday conversation. By coming to know genetic backgrounds, people can control their environments in more healthy ways. Genetic knowledge is, therefore, both informative and empowering

Author(s): Ricki Lewis
Edition: 13
Publisher: McGraw-Hill
Year: 2020

Language: English
Pages: 497

Cover
Title
Copyright
About the Author
Brief Contents
Contents
About the Author
Preface
Applying Human Genetics
The Human Touch
The Lewis Guided Learning System
Part 1: Introduction
Chapter 1: The Information in a Human Genome
1.1 Introducing Genes and Genomes
1.2 Levels of Genetics and Genomics
1.3 Applications of Genetics and Genomics
1.4 A Global Perspective on Genomes
Chapter 2: Cells
2.1 Introducing Cells
2.2 Cell Components
2.3 Cell Division and Death
2.4 Stem Cells
2.5 The Human Microbiome
Chapter 3: Meiosis, Development, and Aging
3.1 The Reproductive System
3.2 Meiosis
3.3 Gametes Mature
3.4 Prenatal Development
3.5 Birth Defects
3.6 Maturation and Aging
Part 2: Transmission Genetics
Chapter 4: Single-Gene Inheritance
4.1 Following the Inheritance of One Gene
4.2 Single-Gene Inheritance Is Rare
4.3 Following the Inheritance of More Than One Gene
4.4 Pedigree Analysis
Chapter 5: Beyond Mendel’s Laws
5.1 When Gene Expression Appears to Alter Mendelian Ratios
5.2 Mitochondrial Genes
5.3 Linkage
Chapter 6: Matters of Sex
6.1 Our Sexual Selves
6.2 Traits Inherited on Sex Chromosomes
6.3 Sex-Limited and Sex-Influenced Traits
6.4 X Inactivation
6.5 Parent-of-Origin Effects
Chapter 7: Complex Traits
7.1 Genes and the Environment Mold Traits
7.2 Polygenic Traits Are Continuously Varying
7.3 Methods to Investigate Complex Traits
7.4 A Closer Look: Body Weight
Chapter 8: Genetics of Behavior
8.1 Genes and Behavior
8.2 Sleep
8.3 Intelligence and Intellectual Disability
8.4 Drug Addiction
8.5 Mood Disorders
8.6 Schizophrenia
8.7 Autism
Part 3: DNA and Chromosomes
Chapter 9: DNA Structure and Replication
9.1 Experiments Identify and Describe the Genetic Material
9.2 DNA Structure
9.3 DNA Replication—Maintaining Genetic Information
9.4 Sequencing DNA
Chapter 10: Gene Action: From
DNA to Protein
10.1 The Importance of Proteins
10.2 Transcription Copies the Information in DNA
10.3 Translation of a Protein
10.4 Processing a Protein
Chapter 11: Gene Expression and Epigenetics
11.1 Gene Expression Through Time and Tissue
11.2 Control of Gene Expression
11.3 Maximizing Genetic Information
11.4 Most of the Human Genome Does Not Encode Protein
Chapter 12: Gene Mutation
12.1 The Nature of Gene Variants
12.2 A Closer Look at Two Mutations
12.3 Allelic Diseases
12.4 Causes of Mutation
12.5 Types of Mutations
12.6 The Importance of Position
12.7 DNA Repair
Chapter 13: Chromosomes
13.1 Portrait of a Chromosome
13.2 Detecting Chromosomes
13.3 Atypical Chromosome Number
13.4 Atypical Chromosome Structure
13.5 Uniparental Disomy—A Double Dose from One Parent
Chapter 14: Genomes
14.1 From Genetics to Genomics
14.2 Analysis of Human Genome Content
14.3 A Genomic View Expands Knowledge
Part 4: Population Genetics
Chapter 15: Constant Allele Frequencies
15.1 Population Genetics Underlies Evolution
15.2 Constant Allele Frequencies
15.3 Applying Hardy-Weinberg Equilibrium
Chapter 16: Changing Allele Frequencies
16.1 Population Matters: Steel Syndrome in East Harlem
16.2 Nonrandom Mating
16.3 Migration
16.4 Genetic Drift
16.5 Mutation
16.6 Natural Selection
16.7 Eugenics
Chapter 17: Human Ancestry
and Evolution
17.1 Human Origins
17.2 Methods to Study Molecular Evolution
17.3 The Peopling of the Planet
17.4 What Makes Us Human?
Chapter 18: The Genetics of
Identity
18.1 Genetics as an Informational Science
18.2 Forensic DNA Typing
18.3 Genetic Genealogy
18.4 Forensic STRs Meet Genetic Genealogy SNPs
Part 5: Immunity and Cancer
Chapter 19: Genetics of Immunity
19.1 The Importance of Cell Surfaces
19.2 The Human Immune System
19.3 Abnormal Immunity
19.4 The Immune Response During Pregnancy
19.5 Altering Immunity
19.6 Using Genomics to Fight Infection
Chapter 20: Cancer Genetics
and Genomics
20.1 Cancer Is an Abnormal Growth That Invades and Spreads
20.2 Cancer at the Cellular Level
20.3 Cancer Genes and Genomes
20.4 Diagnosing and Treating Cancer
Part 6: Genetic Technology
Chapter 21: DNA Technologies
21.1 Patenting DNA
21.2 Modifying DNA
21.3 Monitoring Gene Function
21.4 Gene Silencing and Genome Editing
Chapter 22: Genetic Testing
and Treatment
22.1 Genetic Counseling
22.2 Genetic Testing
22.3 Treating Genetic Disease
22.4 CRISPR-Cas9 in Diagnosis and Treatment
Chapter 23: Reproductive Technologies
23.1 Savior Siblings and More
23.2 Infertility and Subfertility
23.3 Assisted Reproductive Technologies
23.4 Extra Embryos
Index
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